A Facile Ionic Liquid Promoted Synthesis, Cholinesterase
Inhibitory Activity and Molecular Modeling Study of Novel
Highly Functionalized Spiropyrrolidines
A series of novel dimethoxyindanone embedded spiropyrrolidines were synthesized in ionic liquid, [bmim]Br and were evaluated for their inhibitory activities
towards cholinesterases. Among the spiropyrrolidines, compound 4f exhibited the most potent activity with an IC50 value of 1.57 μM against ace...
Full description
Bibliographic Details
| Main Authors: |
I. Almansour, Abdulrahman,
Kumar, Raju Suresh,
Arumugam, Natarajan,
Basiri, Alireza,
Kia, Yalda,
Ali, Mohamed Ashraf,
Farooq, Mehvish,
Murugaiyah, Vikneswaran |
|---|
| Format: | Article
|
|---|
| Language: | English |
|---|
| Published: |
MDPI
2015
|
|---|
| Subjects: | |
|---|
| Online Access: | http://eprints.usm.my/38014/1/A_Facile_Ionic_Liquid_Promoted_Synthesis%2C_Cholinesterase_Inhibitory.pdf
|
|---|