Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.

Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.

Euphorbia hirta is a well-known ethnomedicinal plant with diverse biological activities.The aim of the present study is to investigate the antiradical activities of various solvent extracts of the aerial part of E. hirta as well as to determine the possible cytotoxicity of these extracts. The aeri...

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Bibliographic Details
Main Authors: Perumal, Shanmugapriya, Mahmud, Roziahanim, Pillai Piaru, Suthagar, Wei, Cai Lee, Ramanathan, Surash
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2013
Subjects:
RM300-666 Drugs and their actions
RS1-441 Pharmacy and materia medica
Online Access:http://eprints.usm.my/38343/1/Antiradical_and_Cytotoxic_Activities_of_Varying_Polarity_Extracts_of_the_Aerial_Part_of_Euphorbia_hirta_L..pdf
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Summary:Euphorbia hirta is a well-known ethnomedicinal plant with diverse biological activities.The aim of the present study is to investigate the antiradical activities of various solvent extracts of the aerial part of E. hirta as well as to determine the possible cytotoxicity of these extracts. The aerial part of E. hirta was extracted with different solvent systems in order to increase polarity. The solvents used were hexane, dichloromethane (DCM), ethyl acetate (EA), ethanol (EtOH), and methanol (MeOH). The contents of total phenols and total flavonoids were analyzed byUVspectrophotometry, whereas the potential free radical-scavenging activities of the extracts were evaluated using the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), the

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