Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.

Euphorbia hirta is a well-known ethnomedicinal plant with diverse biological activities.The aim of the present study is to investigate the antiradical activities of various solvent extracts of the aerial part of E. hirta as well as to determine the possible cytotoxicity of these extracts. The aeri...

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Main Authors: Perumal, Shanmugapriya, Mahmud, Roziahanim, Pillai Piaru, Suthagar, Wei, Cai Lee, Ramanathan, Surash
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2013
Subjects:
Online Access:http://eprints.usm.my/38343/1/Antiradical_and_Cytotoxic_Activities_of_Varying_Polarity_Extracts_of_the_Aerial_Part_of_Euphorbia_hirta_L..pdf
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author Perumal, Shanmugapriya
Mahmud, Roziahanim
Pillai Piaru, Suthagar
Wei, Cai Lee
Ramanathan, Surash
author_facet Perumal, Shanmugapriya
Mahmud, Roziahanim
Pillai Piaru, Suthagar
Wei, Cai Lee
Ramanathan, Surash
author_sort Perumal, Shanmugapriya
collection USM
description Euphorbia hirta is a well-known ethnomedicinal plant with diverse biological activities.The aim of the present study is to investigate the antiradical activities of various solvent extracts of the aerial part of E. hirta as well as to determine the possible cytotoxicity of these extracts. The aerial part of E. hirta was extracted with different solvent systems in order to increase polarity. The solvents used were hexane, dichloromethane (DCM), ethyl acetate (EA), ethanol (EtOH), and methanol (MeOH). The contents of total phenols and total flavonoids were analyzed byUVspectrophotometry, whereas the potential free radical-scavenging activities of the extracts were evaluated using the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), the
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spelling usm.eprints-383432018-01-11T06:13:18Z http://eprints.usm.my/38343/ Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L. Perumal, Shanmugapriya Mahmud, Roziahanim Pillai Piaru, Suthagar Wei, Cai Lee Ramanathan, Surash RM300-666 Drugs and their actions RS1-441 Pharmacy and materia medica Euphorbia hirta is a well-known ethnomedicinal plant with diverse biological activities.The aim of the present study is to investigate the antiradical activities of various solvent extracts of the aerial part of E. hirta as well as to determine the possible cytotoxicity of these extracts. The aerial part of E. hirta was extracted with different solvent systems in order to increase polarity. The solvents used were hexane, dichloromethane (DCM), ethyl acetate (EA), ethanol (EtOH), and methanol (MeOH). The contents of total phenols and total flavonoids were analyzed byUVspectrophotometry, whereas the potential free radical-scavenging activities of the extracts were evaluated using the stable free radical 2,2-diphenyl-1-picrylhydrazyl (DPPH), the Hindawi Publishing Corporation 2013 Article PeerReviewed application/pdf en http://eprints.usm.my/38343/1/Antiradical_and_Cytotoxic_Activities_of_Varying_Polarity_Extracts_of_the_Aerial_Part_of_Euphorbia_hirta_L..pdf Perumal, Shanmugapriya and Mahmud, Roziahanim and Pillai Piaru, Suthagar and Wei, Cai Lee and Ramanathan, Surash (2013) Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L. Journal of Chemistry, 2013 (983253). pp. 1-6. ISSN 2090-9063 http://dx.doi.org/10.1155/2013/983253
spellingShingle RM300-666 Drugs and their actions
RS1-441 Pharmacy and materia medica
Perumal, Shanmugapriya
Mahmud, Roziahanim
Pillai Piaru, Suthagar
Wei, Cai Lee
Ramanathan, Surash
Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.
title Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.
title_full Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.
title_fullStr Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.
title_full_unstemmed Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.
title_short Antiradical and Cytotoxic Activities of Varying Polarity Extracts of the Aerial Part of Euphorbia hirta L.
title_sort antiradical and cytotoxic activities of varying polarity extracts of the aerial part of euphorbia hirta l
topic RM300-666 Drugs and their actions
RS1-441 Pharmacy and materia medica
url http://eprints.usm.my/38343/1/Antiradical_and_Cytotoxic_Activities_of_Varying_Polarity_Extracts_of_the_Aerial_Part_of_Euphorbia_hirta_L..pdf
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