Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo
The binding specificity and affinity of aptamers have long been harnessed as the key elements in the development of aptamerbased assays, particularly aptasensing application. One promising avenue that is currently explored based on the specificity and affinity of aptamers is the application of apt...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Hindawi Publishing Corporation
2017
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| Subjects: | |
| Online Access: | http://eprints.usm.my/38359/1/Aptamers_as_the_Agent_in_Decontamination_Assays.pdf |
| _version_ | 1797010016475021312 |
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| author | Mawethu Pascoe, Bilibana Citartan, Marimuthu Tzi, Shien Yeoh Timofey S., Rozhdestvensky Tang, Thean Hock |
| author_facet | Mawethu Pascoe, Bilibana Citartan, Marimuthu Tzi, Shien Yeoh Timofey S., Rozhdestvensky Tang, Thean Hock |
| author_sort | Mawethu Pascoe, Bilibana |
| collection | USM |
| description | The binding specificity and affinity of aptamers have long been harnessed as the key elements in the development of aptamerbased
assays, particularly aptasensing application. One promising avenue that is currently explored based on the specificity and
affinity of aptamers is the application of aptamers in the decontamination assays. Aptamers have been successfully harnessed
as the decontamination agents to remove contaminants from the environment and to decontaminate infectious elements. The
reversible denaturation property inherent in aptamers enables the repeated usage of aptamers, which can immensely save the cost of
decontamination. Analogous to the point-of-care diagnostics, there is no doubt that aptamers can also be deployed in the point-ofcare
aptamer-based decontamination assay, whereby decontamination can be performed anywhere and anytime for instantaneous
decision-making. It is also prophesied that aptamers can also serve more than as a decontaminant, probably as a tool to capture
and kill hazardous elements, particularly pathogenic agents. |
| first_indexed | 2024-03-06T15:13:47Z |
| format | Article |
| id | usm.eprints-38359 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:13:47Z |
| publishDate | 2017 |
| publisher | Hindawi Publishing Corporation |
| record_format | dspace |
| spelling | usm.eprints-383592018-01-12T07:21:41Z http://eprints.usm.my/38359/ Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo Mawethu Pascoe, Bilibana Citartan, Marimuthu Tzi, Shien Yeoh Timofey S., Rozhdestvensky Tang, Thean Hock RK1-715 Dentistry The binding specificity and affinity of aptamers have long been harnessed as the key elements in the development of aptamerbased assays, particularly aptasensing application. One promising avenue that is currently explored based on the specificity and affinity of aptamers is the application of aptamers in the decontamination assays. Aptamers have been successfully harnessed as the decontamination agents to remove contaminants from the environment and to decontaminate infectious elements. The reversible denaturation property inherent in aptamers enables the repeated usage of aptamers, which can immensely save the cost of decontamination. Analogous to the point-of-care diagnostics, there is no doubt that aptamers can also be deployed in the point-ofcare aptamer-based decontamination assay, whereby decontamination can be performed anywhere and anytime for instantaneous decision-making. It is also prophesied that aptamers can also serve more than as a decontaminant, probably as a tool to capture and kill hazardous elements, particularly pathogenic agents. Hindawi Publishing Corporation 2017 Article PeerReviewed application/pdf en http://eprints.usm.my/38359/1/Aptamers_as_the_Agent_in_Decontamination_Assays.pdf Mawethu Pascoe, Bilibana and Citartan, Marimuthu and Tzi, Shien Yeoh and Timofey S., Rozhdestvensky and Tang, Thean Hock (2017) Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo. Journal of Nucleic Acids, 2017 (371207). pp. 1-12. ISSN 2090-0201 https://doi.org/10.1155/2017/3712070 |
| spellingShingle | RK1-715 Dentistry Mawethu Pascoe, Bilibana Citartan, Marimuthu Tzi, Shien Yeoh Timofey S., Rozhdestvensky Tang, Thean Hock Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo |
| title | Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo |
| title_full | Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo |
| title_fullStr | Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo |
| title_full_unstemmed | Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo |
| title_short | Aptamers as the Agent in Decontamination Assays (Apta-Decontamination Assays): From the Environment to the Potential Application In Vivo |
| title_sort | aptamers as the agent in decontamination assays apta decontamination assays from the environment to the potential application in vivo |
| topic | RK1-715 Dentistry |
| url | http://eprints.usm.my/38359/1/Aptamers_as_the_Agent_in_Decontamination_Assays.pdf |
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