Assessment of the Optic Nerve Head Parameters Using Heidelberg Retinal Tomography III in Preterm Children
Background: Variations in optic nerve head morphology and abnormal retinal vascular pattern have been described in preterm children using digital image analysis of fundus photograph, optical coherence tomograph and serial funduscopy. We aimed to compare the optic nerve head parameters in preterm a...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014
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| Online Access: | http://eprints.usm.my/38369/1/Assessment_of_the_Optic_Nerve_Head_Parameters_Using.pdf |
| _version_ | 1825833839165964288 |
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| author | Salem, Alshaarawi Ismail, Shatriah Embong, Zunaina Wan Hitam, Wan Hazabbah |
| author_facet | Salem, Alshaarawi Ismail, Shatriah Embong, Zunaina Wan Hitam, Wan Hazabbah |
| author_sort | Salem, Alshaarawi |
| collection | USM |
| description | Background: Variations in optic nerve head morphology and abnormal retinal vascular pattern have been described in
preterm children using digital image analysis of fundus photograph, optical coherence tomograph and serial funduscopy.
We aimed to compare the optic nerve head parameters in preterm and term Malay children using Heidelberg Retinal
Tomograph III.
Design: A cross sectional study.
Methodology/Principal Findings: Thirty-two preterm Malay children who were born at up to 32 weeks postconception,
and 32 term Malay children aged 8–16 years old were recruited into this cross sectional study, which was conducted in the
Hospital Universiti Sains Malaysia, Malaysia from January to December 2011. Their optic nerves were scanned and analyzed
using a Heidelberg Retinal Tomography (HRT) III (Heidelberg Engineering, Germany). Preterm children showed an increased
rim volume (SD) (0.56 (0.26) vs 0.44 (0.18) mm3, respectively), smaller cup shape (SD) (0.18 (0.07) vs 0.25 (0.06) mm,
respectively), increased height variation contour (SD) (0.44 (0.14) vs 0.35 (0.08) mm, respectively), and increased cup depth
(SD) (0.24 (0.11) vs 0.17 (0.05) mm3, respectively) when compared to their normal peers (p,0.05). There were no significant
differences in the mean disc area, cup area, cup to disc ratio or rim area between the preterm and term children (p.0.05) in
our study.
Conclusions/Significance: Preterm children exhibit different characteristics of optic nerve head parameters with HRT III
analysis. Increased cup depth in preterm children suggests a need for close observation and monitoring. It may raise
suspicion of pediatric glaucoma when proper documentation of intraocular pressure and clinical funduscopy are
unsuccessful in uncooperative children. |
| first_indexed | 2024-03-06T15:13:48Z |
| format | Article |
| id | usm.eprints-38369 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:13:48Z |
| publishDate | 2014 |
| publisher | Public Library of Science (PLoS) |
| record_format | dspace |
| spelling | usm.eprints-383692018-01-15T02:54:27Z http://eprints.usm.my/38369/ Assessment of the Optic Nerve Head Parameters Using Heidelberg Retinal Tomography III in Preterm Children Salem, Alshaarawi Ismail, Shatriah Embong, Zunaina Wan Hitam, Wan Hazabbah RE Ophthalmology Background: Variations in optic nerve head morphology and abnormal retinal vascular pattern have been described in preterm children using digital image analysis of fundus photograph, optical coherence tomograph and serial funduscopy. We aimed to compare the optic nerve head parameters in preterm and term Malay children using Heidelberg Retinal Tomograph III. Design: A cross sectional study. Methodology/Principal Findings: Thirty-two preterm Malay children who were born at up to 32 weeks postconception, and 32 term Malay children aged 8–16 years old were recruited into this cross sectional study, which was conducted in the Hospital Universiti Sains Malaysia, Malaysia from January to December 2011. Their optic nerves were scanned and analyzed using a Heidelberg Retinal Tomography (HRT) III (Heidelberg Engineering, Germany). Preterm children showed an increased rim volume (SD) (0.56 (0.26) vs 0.44 (0.18) mm3, respectively), smaller cup shape (SD) (0.18 (0.07) vs 0.25 (0.06) mm, respectively), increased height variation contour (SD) (0.44 (0.14) vs 0.35 (0.08) mm, respectively), and increased cup depth (SD) (0.24 (0.11) vs 0.17 (0.05) mm3, respectively) when compared to their normal peers (p,0.05). There were no significant differences in the mean disc area, cup area, cup to disc ratio or rim area between the preterm and term children (p.0.05) in our study. Conclusions/Significance: Preterm children exhibit different characteristics of optic nerve head parameters with HRT III analysis. Increased cup depth in preterm children suggests a need for close observation and monitoring. It may raise suspicion of pediatric glaucoma when proper documentation of intraocular pressure and clinical funduscopy are unsuccessful in uncooperative children. Public Library of Science (PLoS) 2014-02 Article PeerReviewed application/pdf en http://eprints.usm.my/38369/1/Assessment_of_the_Optic_Nerve_Head_Parameters_Using.pdf Salem, Alshaarawi and Ismail, Shatriah and Embong, Zunaina and Wan Hitam, Wan Hazabbah (2014) Assessment of the Optic Nerve Head Parameters Using Heidelberg Retinal Tomography III in Preterm Children. PLoS ONE, 9 (2). pp. 1-5. ISSN 1932-6203 http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088056#s3 |
| spellingShingle | RE Ophthalmology Salem, Alshaarawi Ismail, Shatriah Embong, Zunaina Wan Hitam, Wan Hazabbah Assessment of the Optic Nerve Head Parameters Using Heidelberg Retinal Tomography III in Preterm Children |
| title | Assessment of the Optic Nerve Head Parameters Using Heidelberg Retinal Tomography III in Preterm Children |
| title_full | Assessment of the Optic Nerve Head Parameters Using Heidelberg Retinal Tomography III in Preterm Children |
| title_fullStr | Assessment of the Optic Nerve Head Parameters Using Heidelberg Retinal Tomography III in Preterm Children |
| title_full_unstemmed | Assessment of the Optic Nerve Head Parameters Using Heidelberg Retinal Tomography III in Preterm Children |
| title_short | Assessment of the Optic Nerve Head Parameters Using Heidelberg Retinal Tomography III in Preterm Children |
| title_sort | assessment of the optic nerve head parameters using heidelberg retinal tomography iii in preterm children |
| topic | RE Ophthalmology |
| url | http://eprints.usm.my/38369/1/Assessment_of_the_Optic_Nerve_Head_Parameters_Using.pdf |
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