Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation

Kejadian kanser tiroid differentiated telah meningkat dengan ketara di seluruh dunia. Tiyroglobulin (Tg) serum dan imbasan seluruh badan selepas rawatan radioiodin (I-131 Dx WBS) adalah dua jenis siasatan susulan yang dijalani selepas rawatan kanser di peringkat awal (pembedahan pembuangan seluru...

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Main Author: Chan , Guat Choo
Format: Thesis
Language:English
Published: 2017
Subjects:
Online Access:http://eprints.usm.my/40593/1/CHAN_GUAT_CHOO.pdf
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author Chan , Guat Choo
author_facet Chan , Guat Choo
author_sort Chan , Guat Choo
collection USM
description Kejadian kanser tiroid differentiated telah meningkat dengan ketara di seluruh dunia. Tiyroglobulin (Tg) serum dan imbasan seluruh badan selepas rawatan radioiodin (I-131 Dx WBS) adalah dua jenis siasatan susulan yang dijalani selepas rawatan kanser di peringkat awal (pembedahan pembuangan seluruh tiroid dan pemusnahan sisa tiroid dengan radioiodin). Kajian ini bertujuan untuk menilai korelasi dan nilai ramalan Tg terangsang (sTg) 6 bulan selepas pemusnahan sisa tiroid dengan radioiodin untuk menentukan kewujudan penyakit berstruktur (SED) dalam I-131 Dx WBS. Jika sTg mempunyai nilai ramalan yang sangat tinggi terhadap kewujudan penyakit, ia boleh menggantikan I-131 Dx WBS untuk menilai kewujudan penyakit. Nilai ulangan sTg juga ditentukan bagi dua sampel berlainan yang diambil selepas tempoh 6 bulan. Metodologi: The incidence of differentiated thyroid cancer (DTC) has increased substantially worldwide in the past four decades. Serum thyroglobulin (Tg) and radioiodine diagnostic whole body scan (131-I Dx WBS) are two main surveillance tools to investigate for persistent disease after initial therapy - total thyroidectomy followed by radioiodine remnant ablation (RRA). This study evaluates the correlation, predictive value and reliability of stimulated thyroglobulin (sTg) for detection of structural evidence of disease (SED) in 131-I Dx WBS 6 months after initial therapy in the Nuclear Medicine Department Penang Hospital (NMDPH).
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spelling usm.eprints-405932019-04-12T05:25:06Z http://eprints.usm.my/40593/ Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation Chan , Guat Choo RK1-715 Dentistry Kejadian kanser tiroid differentiated telah meningkat dengan ketara di seluruh dunia. Tiyroglobulin (Tg) serum dan imbasan seluruh badan selepas rawatan radioiodin (I-131 Dx WBS) adalah dua jenis siasatan susulan yang dijalani selepas rawatan kanser di peringkat awal (pembedahan pembuangan seluruh tiroid dan pemusnahan sisa tiroid dengan radioiodin). Kajian ini bertujuan untuk menilai korelasi dan nilai ramalan Tg terangsang (sTg) 6 bulan selepas pemusnahan sisa tiroid dengan radioiodin untuk menentukan kewujudan penyakit berstruktur (SED) dalam I-131 Dx WBS. Jika sTg mempunyai nilai ramalan yang sangat tinggi terhadap kewujudan penyakit, ia boleh menggantikan I-131 Dx WBS untuk menilai kewujudan penyakit. Nilai ulangan sTg juga ditentukan bagi dua sampel berlainan yang diambil selepas tempoh 6 bulan. Metodologi: The incidence of differentiated thyroid cancer (DTC) has increased substantially worldwide in the past four decades. Serum thyroglobulin (Tg) and radioiodine diagnostic whole body scan (131-I Dx WBS) are two main surveillance tools to investigate for persistent disease after initial therapy - total thyroidectomy followed by radioiodine remnant ablation (RRA). This study evaluates the correlation, predictive value and reliability of stimulated thyroglobulin (sTg) for detection of structural evidence of disease (SED) in 131-I Dx WBS 6 months after initial therapy in the Nuclear Medicine Department Penang Hospital (NMDPH). 2017 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/40593/1/CHAN_GUAT_CHOO.pdf Chan , Guat Choo (2017) Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation. Masters thesis, Universiti Sains Malaysia.
spellingShingle RK1-715 Dentistry
Chan , Guat Choo
Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation
title Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation
title_full Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation
title_fullStr Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation
title_full_unstemmed Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation
title_short Differentiated Thyroid Cancer: The Predictive Value Of Stimulated Thyroglobulin Six Months After Radioiodine Ablation
title_sort differentiated thyroid cancer the predictive value of stimulated thyroglobulin six months after radioiodine ablation
topic RK1-715 Dentistry
url http://eprints.usm.my/40593/1/CHAN_GUAT_CHOO.pdf
work_keys_str_mv AT changuatchoo differentiatedthyroidcancerthepredictivevalueofstimulatedthyroglobulinsixmonthsafterradioiodineablation