Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors
Latar Belakang: Darah tali pusat (UCB) merupakan sumber alternatif kepada sel tunjang alogenik hematopoetik bagi tujuan pemindahan. Kualiti darah tali pusat yang dikumpulkan bergantung pada kandungan hematopoetiknya yang secara langsung mempengaruhi hasil ‘engraftment’ dan terapeutik. Demi memast...
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| Format: | Thesis |
| Language: | English |
| Published: |
2017
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| Subjects: | |
| Online Access: | http://eprints.usm.my/40605/1/NOR_AZHANI_BINTI_AZMI.pdf |
| _version_ | 1797010472366505984 |
|---|---|
| author | Azmi, Nor Azhani |
| author_facet | Azmi, Nor Azhani |
| author_sort | Azmi, Nor Azhani |
| collection | USM |
| description | Latar Belakang: Darah tali pusat (UCB) merupakan sumber alternatif kepada sel
tunjang alogenik hematopoetik bagi tujuan pemindahan. Kualiti darah tali pusat yang
dikumpulkan bergantung pada kandungan hematopoetiknya yang secara langsung
mempengaruhi hasil ‘engraftment’ dan terapeutik. Demi memastikan kualiti darah tali
pusat yang dikumpulkan terjamin, kriteria penerimaan darah tali pusat telah diwujudkan
di bank tali pusat, Pusat Darah Negara (PDN) yang bersandarkan piawaian
antarabangsa. Namun ia telah menyebabkan kadar penyingkiran unit darah tali pusat
yang dikumpulkan agak tinggi. Kajian ini bertujuan untuk mengenalpasti hubungkait
antara faktor penderma iaitu ibu dan bayi yang boleh mempengaruhi kualiti kandungan
hematopoetik darah tali pusat untuk membantu dalam pemilihan penderma dan
seterusnya mengurangkan pembaziran.
Background: Umbilical cord blood (UCB) is an alternative source of allogeneic
haematopoietic stem cells for transplantation. The quality of collected UCB depends on
its haematopoietic content which directly influences the engraftment and the therapeutic
outcome. To ensure the quality of stored UCB, the acceptance criteria were created at
the UCB bank in National Blood Centre (NBC) based on established international
standard, which resulted in a high discard rate. This study aims to determine the
association of maternal and neonatal factors that could influence the quality of
haematopoietic contents of the UCB collections thus guide the choice of donors and
reduce wastage.
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| first_indexed | 2024-03-06T15:20:17Z |
| format | Thesis |
| id | usm.eprints-40605 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:20:17Z |
| publishDate | 2017 |
| record_format | dspace |
| spelling | usm.eprints-406052019-04-12T05:25:05Z http://eprints.usm.my/40605/ Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors Azmi, Nor Azhani RK1-715 Dentistry Latar Belakang: Darah tali pusat (UCB) merupakan sumber alternatif kepada sel tunjang alogenik hematopoetik bagi tujuan pemindahan. Kualiti darah tali pusat yang dikumpulkan bergantung pada kandungan hematopoetiknya yang secara langsung mempengaruhi hasil ‘engraftment’ dan terapeutik. Demi memastikan kualiti darah tali pusat yang dikumpulkan terjamin, kriteria penerimaan darah tali pusat telah diwujudkan di bank tali pusat, Pusat Darah Negara (PDN) yang bersandarkan piawaian antarabangsa. Namun ia telah menyebabkan kadar penyingkiran unit darah tali pusat yang dikumpulkan agak tinggi. Kajian ini bertujuan untuk mengenalpasti hubungkait antara faktor penderma iaitu ibu dan bayi yang boleh mempengaruhi kualiti kandungan hematopoetik darah tali pusat untuk membantu dalam pemilihan penderma dan seterusnya mengurangkan pembaziran. Background: Umbilical cord blood (UCB) is an alternative source of allogeneic haematopoietic stem cells for transplantation. The quality of collected UCB depends on its haematopoietic content which directly influences the engraftment and the therapeutic outcome. To ensure the quality of stored UCB, the acceptance criteria were created at the UCB bank in National Blood Centre (NBC) based on established international standard, which resulted in a high discard rate. This study aims to determine the association of maternal and neonatal factors that could influence the quality of haematopoietic contents of the UCB collections thus guide the choice of donors and reduce wastage. 2017 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/40605/1/NOR_AZHANI_BINTI_AZMI.pdf Azmi, Nor Azhani (2017) Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RK1-715 Dentistry Azmi, Nor Azhani Quality Of Stored Cord Blood In National Blood Centre Based On Maternal And Neonatal Factors |
| title | Quality Of Stored Cord Blood In National Blood
Centre Based On Maternal And Neonatal Factors |
| title_full | Quality Of Stored Cord Blood In National Blood
Centre Based On Maternal And Neonatal Factors |
| title_fullStr | Quality Of Stored Cord Blood In National Blood
Centre Based On Maternal And Neonatal Factors |
| title_full_unstemmed | Quality Of Stored Cord Blood In National Blood
Centre Based On Maternal And Neonatal Factors |
| title_short | Quality Of Stored Cord Blood In National Blood
Centre Based On Maternal And Neonatal Factors |
| title_sort | quality of stored cord blood in national blood centre based on maternal and neonatal factors |
| topic | RK1-715 Dentistry |
| url | http://eprints.usm.my/40605/1/NOR_AZHANI_BINTI_AZMI.pdf |
| work_keys_str_mv | AT azminorazhani qualityofstoredcordbloodinnationalbloodcentrebasedonmaternalandneonatalfactors |