Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers
The clinical diagnosis of alcohol-dependence (AD) currently relies on AD assessment questionnairesand biomarkers such as Carbohydrate-DeficientTransferrin (CDT), Gamma Glutamyl Transferase (GGT) and Phosphatidylethanol (PEth). However, both methods of diagnosis lackspecificity and sensitivity. Metab...
| Главные авторы: | , , , , , |
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| Формат: | Conference or Workshop Item |
| Язык: | English |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | http://eprints.usm.my/40912/1/Abstract-penang_conference_%281%29.pdf |
| _version_ | 1825834330994245632 |
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| author | Mostafa, Hamza Mohamed Amin Mostafa, Arwa Mohamed Amin Arif, Nor Hayati Chin, Hoe Teh Murugaiyah, Vikneswaran a/l Ibrahim, Baharudin |
| author_facet | Mostafa, Hamza Mohamed Amin Mostafa, Arwa Mohamed Amin Arif, Nor Hayati Chin, Hoe Teh Murugaiyah, Vikneswaran a/l Ibrahim, Baharudin |
| author_sort | Mostafa, Hamza Mohamed Amin |
| collection | USM |
| description | The clinical diagnosis of alcohol-dependence (AD) currently relies on AD assessment questionnairesand biomarkers such as Carbohydrate-DeficientTransferrin (CDT), Gamma Glutamyl Transferase (GGT) and Phosphatidylethanol (PEth). However, both methods of diagnosis lackspecificity and sensitivity. Metabolic fingerprinting using nuclear magnetic resonance spectroscopy (NMR)of plasma may give us a novel andaccurate method for the diagnosis of the disease. Our primary objective was to identify the metabolites/biomarkers that could discriminate between subjects diagnosed asAD, social drinkersnon-dependent and healthy control. |
| first_indexed | 2024-03-06T15:21:08Z |
| format | Conference or Workshop Item |
| id | usm.eprints-40912 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:21:08Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | usm.eprints-409122018-07-05T04:25:49Z http://eprints.usm.my/40912/ Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers Mostafa, Hamza Mohamed Amin Mostafa, Arwa Mohamed Amin Arif, Nor Hayati Chin, Hoe Teh Murugaiyah, Vikneswaran a/l Ibrahim, Baharudin RC Internal medicine The clinical diagnosis of alcohol-dependence (AD) currently relies on AD assessment questionnairesand biomarkers such as Carbohydrate-DeficientTransferrin (CDT), Gamma Glutamyl Transferase (GGT) and Phosphatidylethanol (PEth). However, both methods of diagnosis lackspecificity and sensitivity. Metabolic fingerprinting using nuclear magnetic resonance spectroscopy (NMR)of plasma may give us a novel andaccurate method for the diagnosis of the disease. Our primary objective was to identify the metabolites/biomarkers that could discriminate between subjects diagnosed asAD, social drinkersnon-dependent and healthy control. 2014 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.usm.my/40912/1/Abstract-penang_conference_%281%29.pdf Mostafa, Hamza Mohamed Amin and Mostafa, Arwa Mohamed Amin and Arif, Nor Hayati and Chin, Hoe Teh and Murugaiyah, Vikneswaran a/l and Ibrahim, Baharudin (2014) Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers. In: The Medical Journal of Penang Hospital-Penang Research Day, May 2014, Pulau Pinang, Malaysia. |
| spellingShingle | RC Internal medicine Mostafa, Hamza Mohamed Amin Mostafa, Arwa Mohamed Amin Arif, Nor Hayati Chin, Hoe Teh Murugaiyah, Vikneswaran a/l Ibrahim, Baharudin Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers |
| title | Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers |
| title_full | Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers |
| title_fullStr | Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers |
| title_full_unstemmed | Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers |
| title_short | Metabolomic Analysis of Blood and Urine to identify Alcohol-Dependence Biomarkers |
| title_sort | metabolomic analysis of blood and urine to identify alcohol dependence biomarkers |
| topic | RC Internal medicine |
| url | http://eprints.usm.my/40912/1/Abstract-penang_conference_%281%29.pdf |
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