Phosphorylation And Regulation Of Human Choline Kinase Beta By Protein Kinase A
Kolina kinase (CK) adalah enzim pertama yang terlibat dalam laluan CDP-kolina untuk proses biosintesis fosfatidilkolina yang merupakan komponen utama fosfolipid membran. CK terdiri daripada tiga isoform iaitu CKα1, CKα2 dan CKβ. Pengawalaturan enzim ini adalah penting dari segi fisiologi. Perubah...
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| Format: | Thesis |
| Language: | English |
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2015
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| Online Access: | http://eprints.usm.my/41256/1/Dr._Chang_Ching_Ching__TSTZ.pdf |
| _version_ | 1825834395515224064 |
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| author | Chang , Ching Ching |
| author_facet | Chang , Ching Ching |
| author_sort | Chang , Ching Ching |
| collection | USM |
| description | Kolina kinase (CK) adalah enzim pertama yang terlibat dalam laluan CDP-kolina
untuk proses biosintesis fosfatidilkolina yang merupakan komponen utama fosfolipid
membran. CK terdiri daripada tiga isoform iaitu CKα1, CKα2 dan CKβ.
Pengawalaturan enzim ini adalah penting dari segi fisiologi. Perubahan metabolik
CKα telah dikaitkan dengan pembentukan tumor, manakala mutasi atau pemadaman
gen chkβ boleh menyebabkan distrofi otot.
Choline kinase (CK) is the first enzyme involved in CDP-choline pathway for the
biosynthesis of phosphatidylcholine, the major component of membrane
phospholipid. CK exists as three isoforms, which are CKα1, CKα2 and CKβ. The
regulation of these enzymes is physiologically important. Metabolic alterations of
CKα are associated with tumorigenesis, while mutation or deletion of chkβ gene
leads to the development of muscular dystrophy. |
| first_indexed | 2024-03-06T15:22:06Z |
| format | Thesis |
| id | usm.eprints-41256 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:22:06Z |
| publishDate | 2015 |
| record_format | dspace |
| spelling | usm.eprints-412562019-04-12T05:25:49Z http://eprints.usm.my/41256/ Phosphorylation And Regulation Of Human Choline Kinase Beta By Protein Kinase A Chang , Ching Ching R5-130.5 General works Kolina kinase (CK) adalah enzim pertama yang terlibat dalam laluan CDP-kolina untuk proses biosintesis fosfatidilkolina yang merupakan komponen utama fosfolipid membran. CK terdiri daripada tiga isoform iaitu CKα1, CKα2 dan CKβ. Pengawalaturan enzim ini adalah penting dari segi fisiologi. Perubahan metabolik CKα telah dikaitkan dengan pembentukan tumor, manakala mutasi atau pemadaman gen chkβ boleh menyebabkan distrofi otot. Choline kinase (CK) is the first enzyme involved in CDP-choline pathway for the biosynthesis of phosphatidylcholine, the major component of membrane phospholipid. CK exists as three isoforms, which are CKα1, CKα2 and CKβ. The regulation of these enzymes is physiologically important. Metabolic alterations of CKα are associated with tumorigenesis, while mutation or deletion of chkβ gene leads to the development of muscular dystrophy. 2015-01 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/41256/1/Dr._Chang_Ching_Ching__TSTZ.pdf Chang , Ching Ching (2015) Phosphorylation And Regulation Of Human Choline Kinase Beta By Protein Kinase A. PhD thesis, USM. |
| spellingShingle | R5-130.5 General works Chang , Ching Ching Phosphorylation And Regulation Of Human Choline Kinase Beta By Protein Kinase A |
| title | Phosphorylation And Regulation
Of Human Choline Kinase Beta
By Protein Kinase A
|
| title_full | Phosphorylation And Regulation
Of Human Choline Kinase Beta
By Protein Kinase A
|
| title_fullStr | Phosphorylation And Regulation
Of Human Choline Kinase Beta
By Protein Kinase A
|
| title_full_unstemmed | Phosphorylation And Regulation
Of Human Choline Kinase Beta
By Protein Kinase A
|
| title_short | Phosphorylation And Regulation
Of Human Choline Kinase Beta
By Protein Kinase A
|
| title_sort | phosphorylation and regulation of human choline kinase beta by protein kinase a |
| topic | R5-130.5 General works |
| url | http://eprints.usm.my/41256/1/Dr._Chang_Ching_Ching__TSTZ.pdf |
| work_keys_str_mv | AT changchingching phosphorylationandregulationofhumancholinekinasebetabyproteinkinasea |