Syntheses And Antibacterial Screening Of Juglone Derivatives
The juglone natural product has been used as the starting material in the syntheses of various bioactive quinones like ochromycinone. The present study involves the syntheses of juglone derivatives from both juglone and non-juglone starting materials. The ochromycinone precursor, 1,2,3,4-tetrahydro-...
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| Format: | Thesis |
| Language: | English |
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2010
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| Online Access: | http://eprints.usm.my/41745/1/DANIAL_TAN_TEOH_CHUAN.pdf |
| _version_ | 1825834487387258880 |
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| author | Tan , Daniel Teoh Chuan |
| author_facet | Tan , Daniel Teoh Chuan |
| author_sort | Tan , Daniel Teoh Chuan |
| collection | USM |
| description | The juglone natural product has been used as the starting material in the syntheses of various bioactive quinones like ochromycinone. The present study involves the syntheses of juglone derivatives from both juglone and non-juglone starting materials. The ochromycinone precursor, 1,2,3,4-tetrahydro-8-hydroxy-3-methylbenz[a] anthracene-7,12-dione (19) was synthesised from juglone in two steps. The first step was the Diels-Alder reaction and the second step was the aromatisation reaction. In addition, a new para-nitrojuglone derivative (51) was obtained as the sole isomeric product from the direct nitration of juglone. |
| first_indexed | 2024-03-06T15:23:29Z |
| format | Thesis |
| id | usm.eprints-41745 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:23:29Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | usm.eprints-417452019-04-12T05:26:46Z http://eprints.usm.my/41745/ Syntheses And Antibacterial Screening Of Juglone Derivatives Tan , Daniel Teoh Chuan QD1-65 General Including alchemy The juglone natural product has been used as the starting material in the syntheses of various bioactive quinones like ochromycinone. The present study involves the syntheses of juglone derivatives from both juglone and non-juglone starting materials. The ochromycinone precursor, 1,2,3,4-tetrahydro-8-hydroxy-3-methylbenz[a] anthracene-7,12-dione (19) was synthesised from juglone in two steps. The first step was the Diels-Alder reaction and the second step was the aromatisation reaction. In addition, a new para-nitrojuglone derivative (51) was obtained as the sole isomeric product from the direct nitration of juglone. 2010-11 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/41745/1/DANIAL_TAN_TEOH_CHUAN.pdf Tan , Daniel Teoh Chuan (2010) Syntheses And Antibacterial Screening Of Juglone Derivatives. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | QD1-65 General Including alchemy Tan , Daniel Teoh Chuan Syntheses And Antibacterial Screening Of Juglone Derivatives |
| title | Syntheses And Antibacterial Screening Of Juglone Derivatives |
| title_full | Syntheses And Antibacterial Screening Of Juglone Derivatives |
| title_fullStr | Syntheses And Antibacterial Screening Of Juglone Derivatives |
| title_full_unstemmed | Syntheses And Antibacterial Screening Of Juglone Derivatives |
| title_short | Syntheses And Antibacterial Screening Of Juglone Derivatives |
| title_sort | syntheses and antibacterial screening of juglone derivatives |
| topic | QD1-65 General Including alchemy |
| url | http://eprints.usm.my/41745/1/DANIAL_TAN_TEOH_CHUAN.pdf |
| work_keys_str_mv | AT tandanielteohchuan synthesesandantibacterialscreeningofjuglonederivatives |