Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
Four different types of compounds were successfully synthesized and characterized. The syntheses of these compounds involved benzylation, addition elimination and cyclization reactions. The structures of the synthesized compounds were confirmed by melting points, FTIR, HRMS, 1D and 2D NMR spectrosco...
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| Format: | Thesis |
| Language: | English |
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2010
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| Online Access: | http://eprints.usm.my/42063/1/MOHAMMED_HADI_SAEED_AL%E2%80%93DOUH.pdf |
| _version_ | 1825834547454935040 |
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| author | al-Douh, Mohammed Hadi Saeed |
| author_facet | al-Douh, Mohammed Hadi Saeed |
| author_sort | al-Douh, Mohammed Hadi Saeed |
| collection | USM |
| description | Four different types of compounds were successfully synthesized and characterized. The syntheses of these compounds involved benzylation, addition elimination and cyclization reactions. The structures of the synthesized compounds were confirmed by melting points, FTIR, HRMS, 1D and 2D NMR spectroscopy and X–ray crystallography. The first type of these compounds is 2-benzyloxy-3-
methoxybenzaldehyde 75, which was synthesized by the reaction of o-vanillin with benzyl bromide in acetone as the solvent and K2CO3 as a base in the presence of tetra-n-butylammonium iodide (TBAI) as catalyst. |
| first_indexed | 2024-03-06T15:24:23Z |
| format | Thesis |
| id | usm.eprints-42063 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:24:23Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | usm.eprints-420632019-04-12T05:26:59Z http://eprints.usm.my/42063/ Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives al-Douh, Mohammed Hadi Saeed QD1-999 Chemistry Four different types of compounds were successfully synthesized and characterized. The syntheses of these compounds involved benzylation, addition elimination and cyclization reactions. The structures of the synthesized compounds were confirmed by melting points, FTIR, HRMS, 1D and 2D NMR spectroscopy and X–ray crystallography. The first type of these compounds is 2-benzyloxy-3- methoxybenzaldehyde 75, which was synthesized by the reaction of o-vanillin with benzyl bromide in acetone as the solvent and K2CO3 as a base in the presence of tetra-n-butylammonium iodide (TBAI) as catalyst. 2010 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42063/1/MOHAMMED_HADI_SAEED_AL%E2%80%93DOUH.pdf al-Douh, Mohammed Hadi Saeed (2010) Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | QD1-999 Chemistry al-Douh, Mohammed Hadi Saeed Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives |
| title | Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
| title_full | Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
| title_fullStr | Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
| title_full_unstemmed | Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
| title_short | Synthesis, Characterization And Anti-Proliferation Study Of Some Benzimidazole Derivatives
|
| title_sort | synthesis characterization and anti proliferation study of some benzimidazole derivatives |
| topic | QD1-999 Chemistry |
| url | http://eprints.usm.my/42063/1/MOHAMMED_HADI_SAEED_AL%E2%80%93DOUH.pdf |
| work_keys_str_mv | AT aldouhmohammedhadisaeed synthesischaracterizationandantiproliferationstudyofsomebenzimidazolederivatives |