Role of magnesium in essential hypertension

Beneficial role of magnasium supplementation in prevention of complications in coronary artery disease (Iseri,1984) in ischaemic heart disease (Altura,1988) and in the treatment of patients with AMI (Abraham,1990) has been well documented. One study showed that magnesium supplementation reduced art...

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Main Authors: Karim, M.d Fazlul, Singh, Harbindarjeet, Rahman, Abd Rashid Abd, Sirisinghe, R.G.
Format: Conference or Workshop Item
Language:English
Published: 1999
Subjects:
Online Access:http://eprints.usm.my/42428/1/GP...Role_Of_Magnesium_In_Essential_Hypertension..OCR...pdf
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author Karim, M.d Fazlul
Singh, Harbindarjeet
Rahman, Abd Rashid Abd
Sirisinghe, R.G.
author_facet Karim, M.d Fazlul
Singh, Harbindarjeet
Rahman, Abd Rashid Abd
Sirisinghe, R.G.
author_sort Karim, M.d Fazlul
collection USM
description Beneficial role of magnasium supplementation in prevention of complications in coronary artery disease (Iseri,1984) in ischaemic heart disease (Altura,1988) and in the treatment of patients with AMI (Abraham,1990) has been well documented. One study showed that magnesium supplementation reduced arterial blood pressure in patients with hypertension (Dykner& Waster,1983).Renin profiling, nevertheless,has revealed higher,and lower magnesium levels in low renin and high renin hypertensives respectively (Resnick LM et a1 1983).The significance of this seems to be that the influence of magnesium intake on blood pressure may differ according to the underlying state of magnesium metabolism in hypertensive patients. These observations remain largely unconfirmed. Recently it has been reported that a disordered metabolism of magnesium and calcium ions is present in women with pregnancy induced hypertension (Singh, HJ 1993).So the objective of this study was to investigate the magnesium status in serum, erythrocyte and in urine of untreated hypertensive patients. Work was further extended to investigate the relationship between serum and urinary magnesium levels,plasma renin activity (PRA) and plasma renin concentration (PRC) in normotensive and age and sex-matched untreated hypertensives.
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spelling usm.eprints-424282020-03-20T04:37:46Z http://eprints.usm.my/42428/ Role of magnesium in essential hypertension Karim, M.d Fazlul Singh, Harbindarjeet Rahman, Abd Rashid Abd Sirisinghe, R.G. RC Internal medicine Beneficial role of magnasium supplementation in prevention of complications in coronary artery disease (Iseri,1984) in ischaemic heart disease (Altura,1988) and in the treatment of patients with AMI (Abraham,1990) has been well documented. One study showed that magnesium supplementation reduced arterial blood pressure in patients with hypertension (Dykner& Waster,1983).Renin profiling, nevertheless,has revealed higher,and lower magnesium levels in low renin and high renin hypertensives respectively (Resnick LM et a1 1983).The significance of this seems to be that the influence of magnesium intake on blood pressure may differ according to the underlying state of magnesium metabolism in hypertensive patients. These observations remain largely unconfirmed. Recently it has been reported that a disordered metabolism of magnesium and calcium ions is present in women with pregnancy induced hypertension (Singh, HJ 1993).So the objective of this study was to investigate the magnesium status in serum, erythrocyte and in urine of untreated hypertensive patients. Work was further extended to investigate the relationship between serum and urinary magnesium levels,plasma renin activity (PRA) and plasma renin concentration (PRC) in normotensive and age and sex-matched untreated hypertensives. 1999 Conference or Workshop Item NonPeerReviewed application/pdf en http://eprints.usm.my/42428/1/GP...Role_Of_Magnesium_In_Essential_Hypertension..OCR...pdf Karim, M.d Fazlul and Singh, Harbindarjeet and Rahman, Abd Rashid Abd and Sirisinghe, R.G. (1999) Role of magnesium in essential hypertension. In: Role of magnesium in essential hypertension. (Submitted)
spellingShingle RC Internal medicine
Karim, M.d Fazlul
Singh, Harbindarjeet
Rahman, Abd Rashid Abd
Sirisinghe, R.G.
Role of magnesium in essential hypertension
title Role of magnesium in essential hypertension
title_full Role of magnesium in essential hypertension
title_fullStr Role of magnesium in essential hypertension
title_full_unstemmed Role of magnesium in essential hypertension
title_short Role of magnesium in essential hypertension
title_sort role of magnesium in essential hypertension
topic RC Internal medicine
url http://eprints.usm.my/42428/1/GP...Role_Of_Magnesium_In_Essential_Hypertension..OCR...pdf
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