Phytochemical Study, Antimicrobial And Antiangiogenic Activities Of The Leaf Extracts Of Gynura Segetum

Gynura segetum (daun dewa in Malay) is a herb from family compositae, reputed to possess various medicinal values. This plant is believed of value for treating cancer, diabetes, hypertension, inflammation and skin infection. The leaves of Gynura segetum were evaluated using quality control parame...

Full description

Bibliographic Details
Main Author: Seow , Lay Jing
Format: Thesis
Language:English
Published: 2010
Subjects:
Online Access:http://eprints.usm.my/42447/1/Seow_Lay_Jing24.pdf
_version_ 1797010833018978304
author Seow , Lay Jing
author_facet Seow , Lay Jing
author_sort Seow , Lay Jing
collection USM
description Gynura segetum (daun dewa in Malay) is a herb from family compositae, reputed to possess various medicinal values. This plant is believed of value for treating cancer, diabetes, hypertension, inflammation and skin infection. The leaves of Gynura segetum were evaluated using quality control parameters, which include gravimetric, thin layer chromatographic (TLC) and high-performance liquid chromatographic (HPLC) analysis. The antimicrobial activity of different solvent extracts of leaves of Gynura segetum was evaluated using agar diffusion method. Ethyl acetate fraction exhibited the highest inhibitory effect and therefore further fractionation on this fraction was carried out. Fifteen new subfractions obtained were tested for antimicrobial activity and the MIC of the active subfractions was determined by tube dilution method.
first_indexed 2024-03-06T15:25:27Z
format Thesis
id usm.eprints-42447
institution Universiti Sains Malaysia
language English
last_indexed 2024-03-06T15:25:27Z
publishDate 2010
record_format dspace
spelling usm.eprints-424472019-04-12T05:26:50Z http://eprints.usm.my/42447/ Phytochemical Study, Antimicrobial And Antiangiogenic Activities Of The Leaf Extracts Of Gynura Segetum Seow , Lay Jing RS1-441 Pharmacy and materia medica Gynura segetum (daun dewa in Malay) is a herb from family compositae, reputed to possess various medicinal values. This plant is believed of value for treating cancer, diabetes, hypertension, inflammation and skin infection. The leaves of Gynura segetum were evaluated using quality control parameters, which include gravimetric, thin layer chromatographic (TLC) and high-performance liquid chromatographic (HPLC) analysis. The antimicrobial activity of different solvent extracts of leaves of Gynura segetum was evaluated using agar diffusion method. Ethyl acetate fraction exhibited the highest inhibitory effect and therefore further fractionation on this fraction was carried out. Fifteen new subfractions obtained were tested for antimicrobial activity and the MIC of the active subfractions was determined by tube dilution method. 2010-08 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42447/1/Seow_Lay_Jing24.pdf Seow , Lay Jing (2010) Phytochemical Study, Antimicrobial And Antiangiogenic Activities Of The Leaf Extracts Of Gynura Segetum. Masters thesis, Universiti Sains Malaysia.
spellingShingle RS1-441 Pharmacy and materia medica
Seow , Lay Jing
Phytochemical Study, Antimicrobial And Antiangiogenic Activities Of The Leaf Extracts Of Gynura Segetum
title Phytochemical Study, Antimicrobial And Antiangiogenic Activities Of The Leaf Extracts Of Gynura Segetum
title_full Phytochemical Study, Antimicrobial And Antiangiogenic Activities Of The Leaf Extracts Of Gynura Segetum
title_fullStr Phytochemical Study, Antimicrobial And Antiangiogenic Activities Of The Leaf Extracts Of Gynura Segetum
title_full_unstemmed Phytochemical Study, Antimicrobial And Antiangiogenic Activities Of The Leaf Extracts Of Gynura Segetum
title_short Phytochemical Study, Antimicrobial And Antiangiogenic Activities Of The Leaf Extracts Of Gynura Segetum
title_sort phytochemical study antimicrobial and antiangiogenic activities of the leaf extracts of gynura segetum
topic RS1-441 Pharmacy and materia medica
url http://eprints.usm.my/42447/1/Seow_Lay_Jing24.pdf
work_keys_str_mv AT seowlayjing phytochemicalstudyantimicrobialandantiangiogenicactivitiesoftheleafextractsofgynurasegetum