An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
The potential of liposomal formulation as a drug delivery system for oral administration of poorly bioavailable drugs was studied using griseofulvin as the model drug. An extrusion technique using a self-assembled instrument was evaluated for nanosizing the liposomes. The particle size and size dist...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2011
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/42530/1/SANDY_ONG_GIM_MING.pdf |
| _version_ | 1825834636352159744 |
|---|---|
| author | Ong , Sandy Gim Ming |
| author_facet | Ong , Sandy Gim Ming |
| author_sort | Ong , Sandy Gim Ming |
| collection | USM |
| description | The potential of liposomal formulation as a drug delivery system for oral administration of poorly bioavailable drugs was studied using griseofulvin as the model drug. An extrusion technique using a self-assembled instrument was evaluated for nanosizing the liposomes. The particle size and size distribution of liposomes produced was affected by various processing parameters. Nevertheless, the extrusion method was simple, reproducible and more effective compared to other size-reduction methods evaluated. |
| first_indexed | 2024-03-06T15:25:41Z |
| format | Thesis |
| id | usm.eprints-42530 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:25:41Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | usm.eprints-425302019-04-12T05:26:38Z http://eprints.usm.my/42530/ An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin Ong , Sandy Gim Ming RS1-441 Pharmacy and materia medica The potential of liposomal formulation as a drug delivery system for oral administration of poorly bioavailable drugs was studied using griseofulvin as the model drug. An extrusion technique using a self-assembled instrument was evaluated for nanosizing the liposomes. The particle size and size distribution of liposomes produced was affected by various processing parameters. Nevertheless, the extrusion method was simple, reproducible and more effective compared to other size-reduction methods evaluated. 2011-04 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/42530/1/SANDY_ONG_GIM_MING.pdf Ong , Sandy Gim Ming (2011) An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | RS1-441 Pharmacy and materia medica Ong , Sandy Gim Ming An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin |
| title | An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
|
| title_full | An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
|
| title_fullStr | An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
|
| title_full_unstemmed | An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
|
| title_short | An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
|
| title_sort | investigation of liposomes for oral delivery of a poorly bioavailable model drug griseofulvin |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/42530/1/SANDY_ONG_GIM_MING.pdf |
| work_keys_str_mv | AT ongsandygimming aninvestigationofliposomesfororaldeliveryofapoorlybioavailablemodeldruggriseofulvin AT ongsandygimming investigationofliposomesfororaldeliveryofapoorlybioavailablemodeldruggriseofulvin |