Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri

The aim of this study is to develop ADC calibration plot in diffusion MRI and to examine the signal intensity trend of MR-weighted T1-, T2-, proton density and Fluid Attenuated Inversion Recovery images as a function of time ranged from 1 hour to 60 days. Fresh human blood samples were drawn from fo...

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Main Author: Taib, Hartini Mohd
Format: Thesis
Language:English
Published: 2010
Subjects:
Online Access:http://eprints.usm.my/43043/1/Nur_Hartini_Binti_Mohd_Taib24.pdf
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author Taib, Hartini Mohd
author_facet Taib, Hartini Mohd
author_sort Taib, Hartini Mohd
collection USM
description The aim of this study is to develop ADC calibration plot in diffusion MRI and to examine the signal intensity trend of MR-weighted T1-, T2-, proton density and Fluid Attenuated Inversion Recovery images as a function of time ranged from 1 hour to 60 days. Fresh human blood samples were drawn from four volunteers and divided into 3 different categories namely, blood mixed with Citrate-Phosphate-Dextrose-Adenine (CPDA), blood mixed with thromboplastin and untreated blood as control. A set of T1WI, T2WI, PD, FLAIR and DWI were acquired using 1.0 Tesla MRI system (GE Signa Horizon LX) at Hospital Universiti Sains Malaysia. Measurements of the signal intensity for T1WI, T2WI, PD and FLAIR images were performed using GE ADW 2.0 Software. The reconstruction of the ADC maps and measurement of the ADC values for DWI were carried out using GE ADW 2.0 (Functool) Software. The study demonstrates that there is a significant trend displayed by all types of images. The trend was obviously exhibited in T1WI, PD and DWI. Generally the curves obtained can be divided into three parts.
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spelling usm.eprints-430432019-04-12T05:26:53Z http://eprints.usm.my/43043/ Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri Taib, Hartini Mohd R5-920 Medicine (General) The aim of this study is to develop ADC calibration plot in diffusion MRI and to examine the signal intensity trend of MR-weighted T1-, T2-, proton density and Fluid Attenuated Inversion Recovery images as a function of time ranged from 1 hour to 60 days. Fresh human blood samples were drawn from four volunteers and divided into 3 different categories namely, blood mixed with Citrate-Phosphate-Dextrose-Adenine (CPDA), blood mixed with thromboplastin and untreated blood as control. A set of T1WI, T2WI, PD, FLAIR and DWI were acquired using 1.0 Tesla MRI system (GE Signa Horizon LX) at Hospital Universiti Sains Malaysia. Measurements of the signal intensity for T1WI, T2WI, PD and FLAIR images were performed using GE ADW 2.0 Software. The reconstruction of the ADC maps and measurement of the ADC values for DWI were carried out using GE ADW 2.0 (Functool) Software. The study demonstrates that there is a significant trend displayed by all types of images. The trend was obviously exhibited in T1WI, PD and DWI. Generally the curves obtained can be divided into three parts. 2010-05 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43043/1/Nur_Hartini_Binti_Mohd_Taib24.pdf Taib, Hartini Mohd (2010) Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri. Masters thesis, Universiti Sains Malaysia.
spellingShingle R5-920 Medicine (General)
Taib, Hartini Mohd
Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_full Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_fullStr Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_full_unstemmed Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_short Determination Of Apparent Diffusion Coefficient Of Blood At Its Various Ages Using The Technique Of Diffusion Mri
title_sort determination of apparent diffusion coefficient of blood at its various ages using the technique of diffusion mri
topic R5-920 Medicine (General)
url http://eprints.usm.my/43043/1/Nur_Hartini_Binti_Mohd_Taib24.pdf
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