Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena
Three species from the genus Homalomena, namely, H. pineodora, H. sagittifolia and H. coerulescens were chosen for this particular research since they have long been used in traditional medicine. The essential oils of the leaves and rhizomes of the three species were isolated by hydrodistillation an...
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| Format: | Thesis |
| Language: | English |
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2011
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| Online Access: | http://eprints.usm.my/43189/1/ABDUL%20HAMID.pdf |
| _version_ | 1797010969821446144 |
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| author | ., Abdul Hamid |
| author_facet | ., Abdul Hamid |
| author_sort | ., Abdul Hamid |
| collection | USM |
| description | Three species from the genus Homalomena, namely, H. pineodora, H. sagittifolia and H. coerulescens were chosen for this particular research since they have long been used in traditional medicine. The essential oils of the leaves and rhizomes of the three species were isolated by hydrodistillation and analyzed by capillary GC and GC-MS,
utilizing two columns of different polarities. Isolation and purification of non-volatile phytochemicals were carried out using various solvent systems and chromatographic methods and their structures were determined by using spectroscopic methods such as
FT-IR, one and two dimensional NMR experiments: 1H-NMR, 13C-NMR, DEPT 45, DEPT 90, DEPT 135, 1H-1H-COSY, 1H-1H-NOESY, 1H-13C-HMQC, 1H-13C-HMBC, GC-MS, DP-MS and LR-MS. The essential oils, crude extracts and some of the isolated compounds were assayed for biological activity (antibacterial, acetylcholinesterase enzyme inhibitory activity and anti-inflammatory activity) to evaluate their reported traditional uses. |
| first_indexed | 2024-03-06T15:27:26Z |
| format | Thesis |
| id | usm.eprints-43189 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:27:26Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | usm.eprints-431892019-04-12T05:26:26Z http://eprints.usm.my/43189/ Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena ., Abdul Hamid QD1-999 Chemistry Three species from the genus Homalomena, namely, H. pineodora, H. sagittifolia and H. coerulescens were chosen for this particular research since they have long been used in traditional medicine. The essential oils of the leaves and rhizomes of the three species were isolated by hydrodistillation and analyzed by capillary GC and GC-MS, utilizing two columns of different polarities. Isolation and purification of non-volatile phytochemicals were carried out using various solvent systems and chromatographic methods and their structures were determined by using spectroscopic methods such as FT-IR, one and two dimensional NMR experiments: 1H-NMR, 13C-NMR, DEPT 45, DEPT 90, DEPT 135, 1H-1H-COSY, 1H-1H-NOESY, 1H-13C-HMQC, 1H-13C-HMBC, GC-MS, DP-MS and LR-MS. The essential oils, crude extracts and some of the isolated compounds were assayed for biological activity (antibacterial, acetylcholinesterase enzyme inhibitory activity and anti-inflammatory activity) to evaluate their reported traditional uses. 2011-11 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43189/1/ABDUL%20HAMID.pdf ., Abdul Hamid (2011) Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | QD1-999 Chemistry ., Abdul Hamid Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
| title | Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
| title_full | Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
| title_fullStr | Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
| title_full_unstemmed | Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
| title_short | Phytochemical And Biological Investigation On Three Species Of The Genus Homalomena |
| title_sort | phytochemical and biological investigation on three species of the genus homalomena |
| topic | QD1-999 Chemistry |
| url | http://eprints.usm.my/43189/1/ABDUL%20HAMID.pdf |
| work_keys_str_mv | AT abdulhamid phytochemicalandbiologicalinvestigationonthreespeciesofthegenushomalomena |