Prediction Of Uncontrolled Dyslipidemia Of Cardiac Outpatients And The Adverse Effect Of Pharmaceutical Excipients

Uncontrolled dyslipidemia is still a difficult problem to be achieved during therapy of cardiac patients. Several authors stated contribution of patients’ adherence, physicians’ practice and active ingredients to attain goals of dyslipidemia control, but none combined all these causes. Unfortunat...

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Main Author: Abdulrazzaq, Hadeer Akram
Format: Thesis
Language:English
Published: 2013
Subjects:
Online Access:http://eprints.usm.my/43460/1/Hadeer%20Akram%20Abdulrazzaq24.pdf
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author Abdulrazzaq, Hadeer Akram
author_facet Abdulrazzaq, Hadeer Akram
author_sort Abdulrazzaq, Hadeer Akram
collection USM
description Uncontrolled dyslipidemia is still a difficult problem to be achieved during therapy of cardiac patients. Several authors stated contribution of patients’ adherence, physicians’ practice and active ingredients to attain goals of dyslipidemia control, but none combined all these causes. Unfortunately few studies discussed the effects of pharmaceutical excipients in clinical practice and especially dyslipidemia. Objectives of this study were to determine predictors of uncontrolled dyslipidemia, poor lipid profile, adverse drug reactions (ADRs), and effects of pharmaceutical excipients. Second is implementation of an intervention tool to improve the knowledge of healthcare professionals about pharmaceutical excipients. First objective was carried out at Cardiac Clinic of Hospital Pulau Pinang in Malaysia, while the second was conducted at Hospital Pulau Pinang (Malaysia) and Al-Kadhimiya Teaching Hospital (Iraq). Dyslipidemia control and lipid profile were evaluated depending on the National Cholesterol Education Program (NCEP) guideline. Validated questionnaires were filled by patients to determine their adherence and common ADRs during therapy. Healthcare professionals answered validated questionnaires; one for physicians to determine their practice for dyslipidemia control, and another to assess their knowledge about pharmaceutical excipients. Other information like patients’ characteristics, concurrent medications, diseases, and lipid profile were collected from patients’ progress files.
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spelling usm.eprints-434602019-04-12T05:26:16Z http://eprints.usm.my/43460/ Prediction Of Uncontrolled Dyslipidemia Of Cardiac Outpatients And The Adverse Effect Of Pharmaceutical Excipients Abdulrazzaq, Hadeer Akram RS1-441 Pharmacy and materia medica Uncontrolled dyslipidemia is still a difficult problem to be achieved during therapy of cardiac patients. Several authors stated contribution of patients’ adherence, physicians’ practice and active ingredients to attain goals of dyslipidemia control, but none combined all these causes. Unfortunately few studies discussed the effects of pharmaceutical excipients in clinical practice and especially dyslipidemia. Objectives of this study were to determine predictors of uncontrolled dyslipidemia, poor lipid profile, adverse drug reactions (ADRs), and effects of pharmaceutical excipients. Second is implementation of an intervention tool to improve the knowledge of healthcare professionals about pharmaceutical excipients. First objective was carried out at Cardiac Clinic of Hospital Pulau Pinang in Malaysia, while the second was conducted at Hospital Pulau Pinang (Malaysia) and Al-Kadhimiya Teaching Hospital (Iraq). Dyslipidemia control and lipid profile were evaluated depending on the National Cholesterol Education Program (NCEP) guideline. Validated questionnaires were filled by patients to determine their adherence and common ADRs during therapy. Healthcare professionals answered validated questionnaires; one for physicians to determine their practice for dyslipidemia control, and another to assess their knowledge about pharmaceutical excipients. Other information like patients’ characteristics, concurrent medications, diseases, and lipid profile were collected from patients’ progress files. 2013-05 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43460/1/Hadeer%20Akram%20Abdulrazzaq24.pdf Abdulrazzaq, Hadeer Akram (2013) Prediction Of Uncontrolled Dyslipidemia Of Cardiac Outpatients And The Adverse Effect Of Pharmaceutical Excipients. PhD thesis, Universiti Sains Malaysia.
spellingShingle RS1-441 Pharmacy and materia medica
Abdulrazzaq, Hadeer Akram
Prediction Of Uncontrolled Dyslipidemia Of Cardiac Outpatients And The Adverse Effect Of Pharmaceutical Excipients
title Prediction Of Uncontrolled Dyslipidemia Of Cardiac Outpatients And The Adverse Effect Of Pharmaceutical Excipients
title_full Prediction Of Uncontrolled Dyslipidemia Of Cardiac Outpatients And The Adverse Effect Of Pharmaceutical Excipients
title_fullStr Prediction Of Uncontrolled Dyslipidemia Of Cardiac Outpatients And The Adverse Effect Of Pharmaceutical Excipients
title_full_unstemmed Prediction Of Uncontrolled Dyslipidemia Of Cardiac Outpatients And The Adverse Effect Of Pharmaceutical Excipients
title_short Prediction Of Uncontrolled Dyslipidemia Of Cardiac Outpatients And The Adverse Effect Of Pharmaceutical Excipients
title_sort prediction of uncontrolled dyslipidemia of cardiac outpatients and the adverse effect of pharmaceutical excipients
topic RS1-441 Pharmacy and materia medica
url http://eprints.usm.my/43460/1/Hadeer%20Akram%20Abdulrazzaq24.pdf
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