Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial
Patients with End Stage Renal Disease (ESRD) require lifelong fluid replacement therapy or renal transplant. Almost 60-90 % haemodialysis patients are hypertensive. Studies aimed at elucidating the pathophysiology of hypertension among haemodialysis patients concluded that 90% cases resulted from so...
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| Format: | Thesis |
| Language: | English |
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2018
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| Online Access: | http://eprints.usm.my/43726/1/RAJA%20AHSAN%20AFTAB.pdf |
| _version_ | 1797011058999689216 |
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| author | Aftab, Raja Ahsan |
| author_facet | Aftab, Raja Ahsan |
| author_sort | Aftab, Raja Ahsan |
| collection | USM |
| description | Patients with End Stage Renal Disease (ESRD) require lifelong fluid replacement therapy or renal transplant. Almost 60-90 % haemodialysis patients are hypertensive. Studies aimed at elucidating the pathophysiology of hypertension among haemodialysis patients concluded that 90% cases resulted from sodium and volume overload (volume-dependent), while the majority of the remaining cases have elevated renin activity (renin dependent), leading to renin dependent high blood pressure. Since there is a constant volume variation during dialysis session, there is a strong possibility for activation of Renin Angiotensin Aldosterone System (RAAS) during dialysis that causes high blood pressure even if they are post dialysis euvolemic. |
| first_indexed | 2024-03-06T15:28:46Z |
| format | Thesis |
| id | usm.eprints-43726 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:28:46Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | usm.eprints-437262019-04-12T05:24:52Z http://eprints.usm.my/43726/ Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial Aftab, Raja Ahsan RS1-441 Pharmacy and materia medica Patients with End Stage Renal Disease (ESRD) require lifelong fluid replacement therapy or renal transplant. Almost 60-90 % haemodialysis patients are hypertensive. Studies aimed at elucidating the pathophysiology of hypertension among haemodialysis patients concluded that 90% cases resulted from sodium and volume overload (volume-dependent), while the majority of the remaining cases have elevated renin activity (renin dependent), leading to renin dependent high blood pressure. Since there is a constant volume variation during dialysis session, there is a strong possibility for activation of Renin Angiotensin Aldosterone System (RAAS) during dialysis that causes high blood pressure even if they are post dialysis euvolemic. 2018-01 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/43726/1/RAJA%20AHSAN%20AFTAB.pdf Aftab, Raja Ahsan (2018) Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | RS1-441 Pharmacy and materia medica Aftab, Raja Ahsan Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial |
| title | Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial |
| title_full | Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial |
| title_fullStr | Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial |
| title_full_unstemmed | Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial |
| title_short | Safety And Efficacy Of Losartan (50 Mg) In Post Dialysis Euvolemic Hypertensive Patients: A Single-Blind Randomized Control Trial |
| title_sort | safety and efficacy of losartan 50 mg in post dialysis euvolemic hypertensive patients a single blind randomized control trial |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/43726/1/RAJA%20AHSAN%20AFTAB.pdf |
| work_keys_str_mv | AT aftabrajaahsan safetyandefficacyoflosartan50mginpostdialysiseuvolemichypertensivepatientsasingleblindrandomizedcontroltrial |