Verbal Working Memory in Schizophrenia: Relationship to Cigarette Smoking and Psychopathology
A number of researches suggest smoking serves as a form of self-medication to reduce the side effects of antipsychotic medications, to alleviate negative symptoms, and/or to ameliorate a number of cognitive deficits associated with schizophrenia. Objective: The aim of this study was to investiga...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Malaysian Psychiatric Association
2012
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| Online Access: | http://eprints.usm.my/43880/1/Verbal%20Working%20Memory%20in%20Schizophrenia.pdf |
| _version_ | 1797011085361938432 |
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| author | Hamzah, Hazura Abdullah, Wan Norhaida Wan Jamaluddin, Ruzita Othman, Zahiruddin |
| author_facet | Hamzah, Hazura Abdullah, Wan Norhaida Wan Jamaluddin, Ruzita Othman, Zahiruddin |
| author_sort | Hamzah, Hazura |
| collection | USM |
| description | A number of researches suggest smoking serves as a form of
self-medication to reduce the side effects of antipsychotic medications, to
alleviate negative symptoms, and/or to ameliorate a number of cognitive
deficits associated with schizophrenia. Objective: The aim of this study was to
investigate the association of cigarette smoking with verbal working memory
and psychopathology of patients with schizophrenia. Methods: Fifty-three
patients with schizophrenia were assessed by a single rater using the Malay
Version of Auditory Verbal Learning Test (MVAVLT) and Positive and
Negative Syndrome Scale (PANSS). Smokers (n=30) were compared with
nonsmokers (n=23) on socio-demographic, clinical, psychopathology and
verbal memory variables. Single linear and multiple regression analysis were
performed to determine factors associated with verbal memory performance.
Results: Verbal working memory performance is associated with lower
number of admission to ward, lesser severity of the negative symptoms or
general psychopathology of schizophrenia and use of atypical antipsychotics
in all schizophrenic subjects. Smokers with schizophrenia scored higher than
non- smoker in measures that reflect immediate memory, delayed recall and
recognition memory. However, the association between verbal working
memory performance and smoking status was found to be not significant.
Conclusion: Verbal working memory performance is associated with negative
symptoms but not positive symptoms. This study failed to detect association
of smoking on verbal working memory. |
| first_indexed | 2024-03-06T15:29:10Z |
| format | Article |
| id | usm.eprints-43880 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:29:10Z |
| publishDate | 2012 |
| publisher | Malaysian Psychiatric Association |
| record_format | dspace |
| spelling | usm.eprints-438802019-04-10T03:37:42Z http://eprints.usm.my/43880/ Verbal Working Memory in Schizophrenia: Relationship to Cigarette Smoking and Psychopathology Hamzah, Hazura Abdullah, Wan Norhaida Wan Jamaluddin, Ruzita Othman, Zahiruddin RZ Other systems of medicine A number of researches suggest smoking serves as a form of self-medication to reduce the side effects of antipsychotic medications, to alleviate negative symptoms, and/or to ameliorate a number of cognitive deficits associated with schizophrenia. Objective: The aim of this study was to investigate the association of cigarette smoking with verbal working memory and psychopathology of patients with schizophrenia. Methods: Fifty-three patients with schizophrenia were assessed by a single rater using the Malay Version of Auditory Verbal Learning Test (MVAVLT) and Positive and Negative Syndrome Scale (PANSS). Smokers (n=30) were compared with nonsmokers (n=23) on socio-demographic, clinical, psychopathology and verbal memory variables. Single linear and multiple regression analysis were performed to determine factors associated with verbal memory performance. Results: Verbal working memory performance is associated with lower number of admission to ward, lesser severity of the negative symptoms or general psychopathology of schizophrenia and use of atypical antipsychotics in all schizophrenic subjects. Smokers with schizophrenia scored higher than non- smoker in measures that reflect immediate memory, delayed recall and recognition memory. However, the association between verbal working memory performance and smoking status was found to be not significant. Conclusion: Verbal working memory performance is associated with negative symptoms but not positive symptoms. This study failed to detect association of smoking on verbal working memory. Malaysian Psychiatric Association 2012 Article PeerReviewed application/pdf en http://eprints.usm.my/43880/1/Verbal%20Working%20Memory%20in%20Schizophrenia.pdf Hamzah, Hazura and Abdullah, Wan Norhaida Wan and Jamaluddin, Ruzita and Othman, Zahiruddin (2012) Verbal Working Memory in Schizophrenia: Relationship to Cigarette Smoking and Psychopathology. Malaysian Journal Of Psychiatry, 21 (1). pp. 44-53. ISSN 2232-0385 http://www.mjpsychiatry.org/index.php/mjp/article/view/181 |
| spellingShingle | RZ Other systems of medicine Hamzah, Hazura Abdullah, Wan Norhaida Wan Jamaluddin, Ruzita Othman, Zahiruddin Verbal Working Memory in Schizophrenia: Relationship to Cigarette Smoking and Psychopathology |
| title | Verbal Working Memory in Schizophrenia: Relationship
to Cigarette Smoking and Psychopathology |
| title_full | Verbal Working Memory in Schizophrenia: Relationship
to Cigarette Smoking and Psychopathology |
| title_fullStr | Verbal Working Memory in Schizophrenia: Relationship
to Cigarette Smoking and Psychopathology |
| title_full_unstemmed | Verbal Working Memory in Schizophrenia: Relationship
to Cigarette Smoking and Psychopathology |
| title_short | Verbal Working Memory in Schizophrenia: Relationship
to Cigarette Smoking and Psychopathology |
| title_sort | verbal working memory in schizophrenia relationship to cigarette smoking and psychopathology |
| topic | RZ Other systems of medicine |
| url | http://eprints.usm.my/43880/1/Verbal%20Working%20Memory%20in%20Schizophrenia.pdf |
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