Use of Queatiapine in Treatment of Unremitting Anxiety: A Case Report of Schizophrenia Prodrome
Objective: A 21-year-old man who presented with a 17-month history of unremitting anxiety associated with panic attacks was studied. Result: The anxiety with panic attacks did not abate with escitalopram 15 mg nocte and alprazolam 0.5 mg tds. At month 3, the patient reported low mood and unexplai...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Japan International Cultural Exchange Foundation
2016
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| Subjects: | |
| Online Access: | http://eprints.usm.my/44056/1/Use%20of%20Queatiapine%20in%20Treatment%20of%20Unremitting%20Anxiety.pdf |
| _version_ | 1797011117583630336 |
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| author | Othman, Zahiruddin Jaapar, Sharifah Zubaidiah Syed Husain, Maruzairi Yasin, Mohd Azhar Mohd |
| author_facet | Othman, Zahiruddin Jaapar, Sharifah Zubaidiah Syed Husain, Maruzairi Yasin, Mohd Azhar Mohd |
| author_sort | Othman, Zahiruddin |
| collection | USM |
| description | Objective: A 21-year-old man who presented with a 17-month history of unremitting anxiety associated with panic attacks
was studied.
Result: The anxiety with panic attacks did not abate with escitalopram 15 mg nocte and alprazolam 0.5 mg tds. At month 3,
the patient reported low mood and unexplained sexual arousal in addition to the unremitting anxiety symptoms. His condition
fairly improved with addition of quetiapine. At month 17, transition to psychotic disorder occurred when the patient experienced
hallucinations for the first time. Quetiapine was increased to 500 mg nocte and the anxiety symptoms improved tremendously
before he relapsed 6 months later due to poor compliance.
Conclusion: Unremitting anxiety with depression can be a dominant feature during the schizophrenia prodrome. Atypical
antipsychotic quetiapine is an interesting treatment option due to its status as approved adjunctive treatment for major depressive
disorder and promising efficacy for generalized anxiety disorder. |
| first_indexed | 2024-03-06T15:29:39Z |
| format | Article |
| id | usm.eprints-44056 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:29:39Z |
| publishDate | 2016 |
| publisher | Japan International Cultural Exchange Foundation |
| record_format | dspace |
| spelling | usm.eprints-440562019-04-11T08:49:18Z http://eprints.usm.my/44056/ Use of Queatiapine in Treatment of Unremitting Anxiety: A Case Report of Schizophrenia Prodrome Othman, Zahiruddin Jaapar, Sharifah Zubaidiah Syed Husain, Maruzairi Yasin, Mohd Azhar Mohd RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry Objective: A 21-year-old man who presented with a 17-month history of unremitting anxiety associated with panic attacks was studied. Result: The anxiety with panic attacks did not abate with escitalopram 15 mg nocte and alprazolam 0.5 mg tds. At month 3, the patient reported low mood and unexplained sexual arousal in addition to the unremitting anxiety symptoms. His condition fairly improved with addition of quetiapine. At month 17, transition to psychotic disorder occurred when the patient experienced hallucinations for the first time. Quetiapine was increased to 500 mg nocte and the anxiety symptoms improved tremendously before he relapsed 6 months later due to poor compliance. Conclusion: Unremitting anxiety with depression can be a dominant feature during the schizophrenia prodrome. Atypical antipsychotic quetiapine is an interesting treatment option due to its status as approved adjunctive treatment for major depressive disorder and promising efficacy for generalized anxiety disorder. Japan International Cultural Exchange Foundation 2016-12 Article PeerReviewed application/pdf en http://eprints.usm.my/44056/1/Use%20of%20Queatiapine%20in%20Treatment%20of%20Unremitting%20Anxiety.pdf Othman, Zahiruddin and Jaapar, Sharifah Zubaidiah Syed and Husain, Maruzairi and Yasin, Mohd Azhar Mohd (2016) Use of Queatiapine in Treatment of Unremitting Anxiety: A Case Report of Schizophrenia Prodrome. International Medical Journal, 23 (6). pp. 624-625. ISSN 13412051 http://www.seronjihou.co.jp/IMJ/backnumber-IMJ.html |
| spellingShingle | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry Othman, Zahiruddin Jaapar, Sharifah Zubaidiah Syed Husain, Maruzairi Yasin, Mohd Azhar Mohd Use of Queatiapine in Treatment of Unremitting Anxiety: A Case Report of Schizophrenia Prodrome |
| title | Use of Queatiapine in Treatment of Unremitting Anxiety: A
Case Report of Schizophrenia Prodrome |
| title_full | Use of Queatiapine in Treatment of Unremitting Anxiety: A
Case Report of Schizophrenia Prodrome |
| title_fullStr | Use of Queatiapine in Treatment of Unremitting Anxiety: A
Case Report of Schizophrenia Prodrome |
| title_full_unstemmed | Use of Queatiapine in Treatment of Unremitting Anxiety: A
Case Report of Schizophrenia Prodrome |
| title_short | Use of Queatiapine in Treatment of Unremitting Anxiety: A
Case Report of Schizophrenia Prodrome |
| title_sort | use of queatiapine in treatment of unremitting anxiety a case report of schizophrenia prodrome |
| topic | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| url | http://eprints.usm.my/44056/1/Use%20of%20Queatiapine%20in%20Treatment%20of%20Unremitting%20Anxiety.pdf |
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