Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts
The fruit of Phaleria macrocarpa is used in traditional medicine in Indonesia and the eastern part of Malaysia, as a remedy for the management of diabetes mellitus. This study was therefore carried out to investigate the antidiabetic activity of this fruit in normal and streptozotocin (STZ) -induced...
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| Format: | Thesis |
| Language: | English |
| Published: |
2012
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| Online Access: | http://eprints.usm.my/44884/1/RABYAH%20B.%20ALI%20ANTISHA.pdf |
| Summary: | The fruit of Phaleria macrocarpa is used in traditional medicine in Indonesia and the eastern part of Malaysia, as a remedy for the management of diabetes mellitus. This study was therefore carried out to investigate the antidiabetic activity of this fruit in normal and streptozotocin (STZ) -induced diabetic rats. The pulverized dried fruits were sequentially extracted in petroleum ether, methanol and water. None of the extracts (1 g/kg) exerted an effect on blood glucose of normal rats. The methanol and water extracts significantly inhibited the rise of blood glucose after glucose loading in intra-peritoneal glucose tolerance tests (IPGTT) in normal rats. |
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