Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts
The fruit of Phaleria macrocarpa is used in traditional medicine in Indonesia and the eastern part of Malaysia, as a remedy for the management of diabetes mellitus. This study was therefore carried out to investigate the antidiabetic activity of this fruit in normal and streptozotocin (STZ) -induced...
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| Format: | Thesis |
| Language: | English |
| Published: |
2012
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| Online Access: | http://eprints.usm.my/44884/1/RABYAH%20B.%20ALI%20ANTISHA.pdf |
| _version_ | 1825835051896537088 |
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| author | Ali Antisha, Rabyah B. |
| author_facet | Ali Antisha, Rabyah B. |
| author_sort | Ali Antisha, Rabyah B. |
| collection | USM |
| description | The fruit of Phaleria macrocarpa is used in traditional medicine in Indonesia and the eastern part of Malaysia, as a remedy for the management of diabetes mellitus. This study was therefore carried out to investigate the antidiabetic activity of this fruit in normal and streptozotocin (STZ) -induced diabetic rats. The pulverized dried fruits were sequentially extracted in petroleum ether, methanol and water. None of the extracts (1 g/kg) exerted an effect on blood glucose of normal rats. The methanol and water extracts significantly inhibited the rise of blood glucose after glucose loading in intra-peritoneal glucose tolerance tests (IPGTT) in normal rats. |
| first_indexed | 2024-03-06T15:31:55Z |
| format | Thesis |
| id | usm.eprints-44884 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:31:55Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | usm.eprints-448842019-07-05T02:26:15Z http://eprints.usm.my/44884/ Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts Ali Antisha, Rabyah B. RS1-441 Pharmacy and materia medica The fruit of Phaleria macrocarpa is used in traditional medicine in Indonesia and the eastern part of Malaysia, as a remedy for the management of diabetes mellitus. This study was therefore carried out to investigate the antidiabetic activity of this fruit in normal and streptozotocin (STZ) -induced diabetic rats. The pulverized dried fruits were sequentially extracted in petroleum ether, methanol and water. None of the extracts (1 g/kg) exerted an effect on blood glucose of normal rats. The methanol and water extracts significantly inhibited the rise of blood glucose after glucose loading in intra-peritoneal glucose tolerance tests (IPGTT) in normal rats. 2012-06 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/44884/1/RABYAH%20B.%20ALI%20ANTISHA.pdf Ali Antisha, Rabyah B. (2012) Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RS1-441 Pharmacy and materia medica Ali Antisha, Rabyah B. Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts |
| title | Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts |
| title_full | Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts |
| title_fullStr | Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts |
| title_full_unstemmed | Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts |
| title_short | Antidiabetic Activity Of Phaleria Macrocarpa (Scheff.) Boerl Fruit Extracts |
| title_sort | antidiabetic activity of phaleria macrocarpa scheff boerl fruit extracts |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/44884/1/RABYAH%20B.%20ALI%20ANTISHA.pdf |
| work_keys_str_mv | AT aliantisharabyahb antidiabeticactivityofphaleriamacrocarpascheffboerlfruitextracts |