Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation
Cell-based therapy of mesenchymal stem cells (MSCs) has been shown to enhance the endogenous repair process by increasing the limited regenerative capacity of the lung in chronic lung disorders as well as following injury. However, the underlying cellular and molecular mechanisms of MSCs to enhance...
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| Format: | Thesis |
| Language: | English |
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2018
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| Online Access: | http://eprints.usm.my/45036/1/NUR%20SHUHAIDATUL%20SARMIZA%20ABDUL%20HALIM.pdf |
| _version_ | 1825835078533513216 |
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| author | Abdul Halim, Nur Shuhaidatul Sarmiza |
| author_facet | Abdul Halim, Nur Shuhaidatul Sarmiza |
| author_sort | Abdul Halim, Nur Shuhaidatul Sarmiza |
| collection | USM |
| description | Cell-based therapy of mesenchymal stem cells (MSCs) has been shown to enhance the endogenous repair process by increasing the limited regenerative capacity of the lung in chronic lung disorders as well as following injury. However, the underlying cellular and molecular mechanisms of MSCs to enhance airway regeneration and repair are remain unclear. This study was aimed to investigate the effect of delivering human adipose-derived MSCs (hAD-MSCs) alone and in combination with vasculoprotective factor, the ANGPT1, by aerosol technique in a rabbit model of asthma related-airway inflammation. |
| first_indexed | 2024-03-06T15:32:20Z |
| format | Thesis |
| id | usm.eprints-45036 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:32:20Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | usm.eprints-450362019-07-24T01:07:50Z http://eprints.usm.my/45036/ Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation Abdul Halim, Nur Shuhaidatul Sarmiza R735-854 Medical education. Medical schools. Research Cell-based therapy of mesenchymal stem cells (MSCs) has been shown to enhance the endogenous repair process by increasing the limited regenerative capacity of the lung in chronic lung disorders as well as following injury. However, the underlying cellular and molecular mechanisms of MSCs to enhance airway regeneration and repair are remain unclear. This study was aimed to investigate the effect of delivering human adipose-derived MSCs (hAD-MSCs) alone and in combination with vasculoprotective factor, the ANGPT1, by aerosol technique in a rabbit model of asthma related-airway inflammation. 2018-09 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45036/1/NUR%20SHUHAIDATUL%20SARMIZA%20ABDUL%20HALIM.pdf Abdul Halim, Nur Shuhaidatul Sarmiza (2018) Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | R735-854 Medical education. Medical schools. Research Abdul Halim, Nur Shuhaidatul Sarmiza Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation |
| title | Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation |
| title_full | Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation |
| title_fullStr | Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation |
| title_full_unstemmed | Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation |
| title_short | Cell-Based Therapy Of Human Adipose- Derived Mesenchymal Stem Cell Expressing Angiopoietin-1 In An Experimental Model Of Airway Inflammation |
| title_sort | cell based therapy of human adipose derived mesenchymal stem cell expressing angiopoietin 1 in an experimental model of airway inflammation |
| topic | R735-854 Medical education. Medical schools. Research |
| url | http://eprints.usm.my/45036/1/NUR%20SHUHAIDATUL%20SARMIZA%20ABDUL%20HALIM.pdf |
| work_keys_str_mv | AT abdulhalimnurshuhaidatulsarmiza cellbasedtherapyofhumanadiposederivedmesenchymalstemcellexpressingangiopoietin1inanexperimentalmodelofairwayinflammation |