Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes

Gestational diabetes mellitus (GDM) is one of the common medical complications occurring during pregnancy, affecting approximately 1-18% of all pregnancies; depending on the population. Increased arterial stiffening has been demonstrated consistently in both Type 1 and Type 2 diabetes in a number of...

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Main Author: Aziz, Salmi Ab
Format: Thesis
Language:English
Published: 2011
Subjects:
Online Access:http://eprints.usm.my/45680/1/Salmi%20Ab%20Aziz_HJ.pdf
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author Aziz, Salmi Ab
author_facet Aziz, Salmi Ab
author_sort Aziz, Salmi Ab
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description Gestational diabetes mellitus (GDM) is one of the common medical complications occurring during pregnancy, affecting approximately 1-18% of all pregnancies; depending on the population. Increased arterial stiffening has been demonstrated consistently in both Type 1 and Type 2 diabetes in a number of studies. Arterial stiffness has been shown to precede cardiovascular diseases. The assessment of arterial stiffness allows early detection of cardiovascular disease and may help in preventive strategies. Pulse wave velocity (PWV) and pulse wave analysis (PWA) are non invasive method used to assess arterial stiffness. Inflammatory and the atherogenic markers may influence vascular function and arterial stiffness. The objectives of this thesis were to determine whether gestational diabetes mellitus (GDM) is associated with increased arterial stiffness, inflammatory and atherogenic markers compared to age and gestational age matched controls. Inflammatory and atherogenic markers measured in this study include tumor necrosis factor alpha (TNF-α), high sensitivity C-reactive protein (hsCRP) and plasminogen activator inhibitor-1 (PAI-1) as a parameters.
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spelling usm.eprints-456802019-10-17T07:41:30Z http://eprints.usm.my/45680/ Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes Aziz, Salmi Ab R735-854 Medical education. Medical schools. Research Gestational diabetes mellitus (GDM) is one of the common medical complications occurring during pregnancy, affecting approximately 1-18% of all pregnancies; depending on the population. Increased arterial stiffening has been demonstrated consistently in both Type 1 and Type 2 diabetes in a number of studies. Arterial stiffness has been shown to precede cardiovascular diseases. The assessment of arterial stiffness allows early detection of cardiovascular disease and may help in preventive strategies. Pulse wave velocity (PWV) and pulse wave analysis (PWA) are non invasive method used to assess arterial stiffness. Inflammatory and the atherogenic markers may influence vascular function and arterial stiffness. The objectives of this thesis were to determine whether gestational diabetes mellitus (GDM) is associated with increased arterial stiffness, inflammatory and atherogenic markers compared to age and gestational age matched controls. Inflammatory and atherogenic markers measured in this study include tumor necrosis factor alpha (TNF-α), high sensitivity C-reactive protein (hsCRP) and plasminogen activator inhibitor-1 (PAI-1) as a parameters. 2011-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/45680/1/Salmi%20Ab%20Aziz_HJ.pdf Aziz, Salmi Ab (2011) Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes. Masters thesis, Universiti Sains Malaysia.
spellingShingle R735-854 Medical education. Medical schools. Research
Aziz, Salmi Ab
Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_full Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_fullStr Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_full_unstemmed Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_short Arterial Stiffness, Inflammatory And Atherogenic Markers In Gestational Diabetes
title_sort arterial stiffness inflammatory and atherogenic markers in gestational diabetes
topic R735-854 Medical education. Medical schools. Research
url http://eprints.usm.my/45680/1/Salmi%20Ab%20Aziz_HJ.pdf
work_keys_str_mv AT azizsalmiab arterialstiffnessinflammatoryandatherogenicmarkersingestationaldiabetes