Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI
Background: Diffusion tensor imaging is a standard method for evaluation of musculoskeletal pathology. The objective of this study is to determine the optimal b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff muscles in healthy subjects on 3.0 Tesla MRI. Meth...
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| Format: | Thesis |
| Language: | English |
| Published: |
2018
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| Online Access: | http://eprints.usm.my/46504/1/Dr.%20Mohd%20Nazlin%20Kamarudin-24%20pages.pdf |
| _version_ | 1825905574007537664 |
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| author | Kamarudin, Mohd Nazlin |
| author_facet | Kamarudin, Mohd Nazlin |
| author_sort | Kamarudin, Mohd Nazlin |
| collection | USM |
| description | Background: Diffusion tensor imaging is a standard method for evaluation of
musculoskeletal pathology. The objective of this study is to determine the optimal
b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff
muscles in healthy subjects on 3.0 Tesla MRI.
Methodology: 38 healthy volunteers were included in this prospective study. Diffusion
tensor imaging (DTI) of the rotator cuff muscles (subscapularis, supraspinatus and
infraspinatus muscles) was performed with single-shot spin-echo echo-planar imaging
sequences in 16 and 32 diffusion directions. Three different b-values were selected for
each diffusion direction: b-value 400 s/mm2, 600s/mm2 and 800s/mm2. Signal to noise
ratio (SNR) was measured in each muscle at different b-values and number of diffusion
direction, and average SNR were calculated. Statistical analysis was performed with
one-way ANOVA and paired t-test. Mean and standard deviation were obtained for each
DTI parameters, and level of significance was determined (p < 0.05).
Results: The signal to noise ratio was highest for all three muscles at b-value 400s/mm2
(subscapularis, 40.255; supraspinatus, 38.203; and infraspinatus, 48.232) followed by
b-value 600s/mm2 and 800s/mm2. The use of 32 number of diffusion directions had
shown to improve SNR value compared to 16 diffusion directions (P<0.05).
Conclusions: The optimal combination of b value and number of diffusion directions in
DTI of rotator cuff muscles on 3.0 Tesla MRI is 400s/mm2 and 32 directions
respectively. |
| first_indexed | 2024-03-06T15:36:29Z |
| format | Thesis |
| id | usm.eprints-46504 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:36:29Z |
| publishDate | 2018 |
| record_format | dspace |
| spelling | usm.eprints-465042020-03-16T07:53:39Z http://eprints.usm.my/46504/ Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI Kamarudin, Mohd Nazlin RC Internal medicine Background: Diffusion tensor imaging is a standard method for evaluation of musculoskeletal pathology. The objective of this study is to determine the optimal b-value and number of diffusion direction for diffusion tensor imaging of rotator cuff muscles in healthy subjects on 3.0 Tesla MRI. Methodology: 38 healthy volunteers were included in this prospective study. Diffusion tensor imaging (DTI) of the rotator cuff muscles (subscapularis, supraspinatus and infraspinatus muscles) was performed with single-shot spin-echo echo-planar imaging sequences in 16 and 32 diffusion directions. Three different b-values were selected for each diffusion direction: b-value 400 s/mm2, 600s/mm2 and 800s/mm2. Signal to noise ratio (SNR) was measured in each muscle at different b-values and number of diffusion direction, and average SNR were calculated. Statistical analysis was performed with one-way ANOVA and paired t-test. Mean and standard deviation were obtained for each DTI parameters, and level of significance was determined (p < 0.05). Results: The signal to noise ratio was highest for all three muscles at b-value 400s/mm2 (subscapularis, 40.255; supraspinatus, 38.203; and infraspinatus, 48.232) followed by b-value 600s/mm2 and 800s/mm2. The use of 32 number of diffusion directions had shown to improve SNR value compared to 16 diffusion directions (P<0.05). Conclusions: The optimal combination of b value and number of diffusion directions in DTI of rotator cuff muscles on 3.0 Tesla MRI is 400s/mm2 and 32 directions respectively. 2018 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/46504/1/Dr.%20Mohd%20Nazlin%20Kamarudin-24%20pages.pdf Kamarudin, Mohd Nazlin (2018) Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RC Internal medicine Kamarudin, Mohd Nazlin Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI |
| title | Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI |
| title_full | Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI |
| title_fullStr | Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI |
| title_full_unstemmed | Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI |
| title_short | Diffusion tensor imaging of the rotator cuff muscles : optimisation of b value and number of diffusion direction for imaging at 3 Tesla MRI |
| title_sort | diffusion tensor imaging of the rotator cuff muscles optimisation of b value and number of diffusion direction for imaging at 3 tesla mri |
| topic | RC Internal medicine |
| url | http://eprints.usm.my/46504/1/Dr.%20Mohd%20Nazlin%20Kamarudin-24%20pages.pdf |
| work_keys_str_mv | AT kamarudinmohdnazlin diffusiontensorimagingoftherotatorcuffmusclesoptimisationofbvalueandnumberofdiffusiondirectionforimagingat3teslamri |