Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts
In Malaysia, hypertension is an increasingly important medical and public health issue and there is an imminent need to decrease its prevalence. In this study, the local herbs in Malaysia such as Clinacanthus nutans Lindau, Strobilanthes cripus, Murdannia bacteata, Elephantopus scaber Linn., Pereski...
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| Format: | Thesis |
| Language: | English |
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2017
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| Online Access: | http://eprints.usm.my/48045/1/ANTIHYPERTENSIVE%20AND%20VASODILATORY.pdf%20cut.pdf |
| _version_ | 1797011879161233408 |
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| author | Ch’ng, Yung Sing |
| author_facet | Ch’ng, Yung Sing |
| author_sort | Ch’ng, Yung Sing |
| collection | USM |
| description | In Malaysia, hypertension is an increasingly important medical and public health issue and there is an imminent need to decrease its prevalence. In this study, the local herbs in Malaysia such as Clinacanthus nutans Lindau, Strobilanthes cripus, Murdannia bacteata, Elephantopus scaber Linn., Pereskia bleo, Pereskia grandifolia Haw., Vernonia amygdalina, and Swietenia macrophylla King seeds were selected and their extracts (water extracts, 50% ethanol extracts, and 95 % ethanol extracts) underwent preliminary testing to screen for their antihypertensive activities and their vasorelaxation. The results showed that the seeds of Swietenia macrophylla King has the highest potential in vasorelaxation, followed by Vernonia amygdalina. This study found that, crude VAE and SM50, which contain multiple chemical components, exhibited a stronger vasorelaxant effect on isolated aortic rings due to their possible involvement of multiple mechanisms. |
| first_indexed | 2024-03-06T15:40:47Z |
| format | Thesis |
| id | usm.eprints-48045 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:40:47Z |
| publishDate | 2017 |
| record_format | dspace |
| spelling | usm.eprints-480452021-01-04T01:55:45Z http://eprints.usm.my/48045/ Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts Ch’ng, Yung Sing RS1-441 Pharmacy and materia medica In Malaysia, hypertension is an increasingly important medical and public health issue and there is an imminent need to decrease its prevalence. In this study, the local herbs in Malaysia such as Clinacanthus nutans Lindau, Strobilanthes cripus, Murdannia bacteata, Elephantopus scaber Linn., Pereskia bleo, Pereskia grandifolia Haw., Vernonia amygdalina, and Swietenia macrophylla King seeds were selected and their extracts (water extracts, 50% ethanol extracts, and 95 % ethanol extracts) underwent preliminary testing to screen for their antihypertensive activities and their vasorelaxation. The results showed that the seeds of Swietenia macrophylla King has the highest potential in vasorelaxation, followed by Vernonia amygdalina. This study found that, crude VAE and SM50, which contain multiple chemical components, exhibited a stronger vasorelaxant effect on isolated aortic rings due to their possible involvement of multiple mechanisms. 2017-11 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/48045/1/ANTIHYPERTENSIVE%20AND%20VASODILATORY.pdf%20cut.pdf Ch’ng, Yung Sing (2017) Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RS1-441 Pharmacy and materia medica Ch’ng, Yung Sing Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts |
| title | Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts |
| title_full | Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts |
| title_fullStr | Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts |
| title_full_unstemmed | Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts |
| title_short | Antihypertensive And Vasodilatory Effects Of Vernonia Amygdalina And Swietenia Macrophylla Extracts |
| title_sort | antihypertensive and vasodilatory effects of vernonia amygdalina and swietenia macrophylla extracts |
| topic | RS1-441 Pharmacy and materia medica |
| url | http://eprints.usm.my/48045/1/ANTIHYPERTENSIVE%20AND%20VASODILATORY.pdf%20cut.pdf |
| work_keys_str_mv | AT chngyungsing antihypertensiveandvasodilatoryeffectsofvernoniaamygdalinaandswieteniamacrophyllaextracts |