Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses

The uniparenlally inherited mitochondrial DNA (mtDNA) is in the limelight for the past two decades, in studies relating to demographic bistoJy of mankind and in foreosic kinship testing. Jn this study, human mtDNA hypervariable segments I, 2, and 3 (HVI, HV1, and HV3) were anal)'7.ed in 24...

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Main Author: Zainuddin, Zafarina
Format: Article
Language:English
Published: Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2011
Subjects:
Online Access:http://eprints.usm.my/50562/1/DR.%20ZAFARINA%20ZAINUDDIN-Eprints.pdf
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author Zainuddin, Zafarina
author_facet Zainuddin, Zafarina
author_sort Zainuddin, Zafarina
collection USM
description The uniparenlally inherited mitochondrial DNA (mtDNA) is in the limelight for the past two decades, in studies relating to demographic bistoJy of mankind and in foreosic kinship testing. Jn this study, human mtDNA hypervariable segments I, 2, and 3 (HVI, HV1, and HV3) were anal)'7.ed in 248 uorelated Malay individuals in Peninsular Malaysia. Combined analyses of HVI, HV2, and HV3 · revealed a total of 180 mtDNA haplotypes with 149 unique haplotypes and 31 haplotypes occmring in more than one individual. The geoetic diversity was estimated to be 99.47%, and the probability of any two individuals sharing the same mtDNA haplotype was 0.93%. The most frequeot mtDNA haplotype (73, 146, 150, 195, 263, 315.IC, 16140, 16182C, 16183C, 16189, 16217, 16274, and 16335) was shared by 11 (4.44%) individuals. The nucleotide diversity and mean of pair-wise differences were found to be 0.0
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spelling usm.eprints-505622021-11-10T07:08:57Z http://eprints.usm.my/50562/ Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses Zainuddin, Zafarina R Medicine The uniparenlally inherited mitochondrial DNA (mtDNA) is in the limelight for the past two decades, in studies relating to demographic bistoJy of mankind and in foreosic kinship testing. Jn this study, human mtDNA hypervariable segments I, 2, and 3 (HVI, HV1, and HV3) were anal)'7.ed in 248 uorelated Malay individuals in Peninsular Malaysia. Combined analyses of HVI, HV2, and HV3 · revealed a total of 180 mtDNA haplotypes with 149 unique haplotypes and 31 haplotypes occmring in more than one individual. The geoetic diversity was estimated to be 99.47%, and the probability of any two individuals sharing the same mtDNA haplotype was 0.93%. The most frequeot mtDNA haplotype (73, 146, 150, 195, 263, 315.IC, 16140, 16182C, 16183C, 16189, 16217, 16274, and 16335) was shared by 11 (4.44%) individuals. The nucleotide diversity and mean of pair-wise differences were found to be 0.0 Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2011 Article NonPeerReviewed application/pdf en http://eprints.usm.my/50562/1/DR.%20ZAFARINA%20ZAINUDDIN-Eprints.pdf Zainuddin, Zafarina (2011) Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses. Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses.
spellingShingle R Medicine
Zainuddin, Zafarina
Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses
title Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses
title_full Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses
title_fullStr Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses
title_full_unstemmed Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses
title_short Tracing the origin of the malay race through the morphological, historical, socio-cultural and genetic analyses
title_sort tracing the origin of the malay race through the morphological historical socio cultural and genetic analyses
topic R Medicine
url http://eprints.usm.my/50562/1/DR.%20ZAFARINA%20ZAINUDDIN-Eprints.pdf
work_keys_str_mv AT zainuddinzafarina tracingtheoriginofthemalayracethroughthemorphologicalhistoricalsocioculturalandgeneticanalyses