Semi-quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar MAPS
Aim: The aim of this study is to assess the validation of summed segmental scores in detection accuracy CAD from different reconstructed polar maps. Method: The summed scores (SSS, SRS and SDS) were obtained from standard filtered backprojection reconstruction (FBP) and iterative reconstruction wit...
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| Format: | Thesis |
| Language: | English |
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2020
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| Online Access: | http://eprints.usm.my/50988/1/Nur%20Syazana-24%20pages.pdf |
| _version_ | 1825906399612239872 |
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| author | Zahir, Nur Syazana Mohd |
| author_facet | Zahir, Nur Syazana Mohd |
| author_sort | Zahir, Nur Syazana Mohd |
| collection | USM |
| description | Aim: The aim of this study is to assess the validation of summed segmental scores in detection accuracy CAD from different reconstructed polar maps.
Method: The summed scores (SSS, SRS and SDS) were obtained from standard filtered backprojection reconstruction (FBP) and iterative reconstruction with CT-AC that being performed on the raw emission data of 30 patients (15 male and 15 females) with known or suspected coronary artery disease who had undergone two-day stress-rest or rest-stress 99mTc-MIBI myocardial perfusion SPECT. The reconstruction algorithms and the resulting projected polar maps were used to estimate the radioactivity distribution within the left ventricular myocardium of the heart.
Result: Mean ± SD for all summed scores is higher in FBP than CT-AC with SSS in FBP 32.60 ± 5.360, SRS FBP 31.60 ± 5.069 and SDS FBP 3.87 ± 3.159. Meanwhile for SSS in CT-AC is 28.27 ± 5.245, SRS CT-AC 27.20 ± 4.397 and SDS CT-AC 3.27 ± 2.449. There is statistically significant difference of SSS and SRS between FBP and CT-AC tested using Mann-Whitney test (p value = 0.002 for SSS and p-value = 0.001 for SRS). However, there is no statistically significant difference of SDS between FBP and CT-AC tested using Mann-Whitney test (p value = 0.633).
Conclusion: Summed scores studies reconstructed with FBP are statistically not significantly different from AC. However, compensation for attenuation artifact is much better with iterative reconstruction CT-AC that FBP as CT-AC for SPECT MPI allows improved specificity of RCA territory compared with FBP reconstruction SPECT MPI. |
| first_indexed | 2024-03-06T15:49:03Z |
| format | Thesis |
| id | usm.eprints-50988 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:49:03Z |
| publishDate | 2020 |
| record_format | dspace |
| spelling | usm.eprints-509882021-12-29T02:09:46Z http://eprints.usm.my/50988/ Semi-quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar MAPS Zahir, Nur Syazana Mohd R Medicine Aim: The aim of this study is to assess the validation of summed segmental scores in detection accuracy CAD from different reconstructed polar maps. Method: The summed scores (SSS, SRS and SDS) were obtained from standard filtered backprojection reconstruction (FBP) and iterative reconstruction with CT-AC that being performed on the raw emission data of 30 patients (15 male and 15 females) with known or suspected coronary artery disease who had undergone two-day stress-rest or rest-stress 99mTc-MIBI myocardial perfusion SPECT. The reconstruction algorithms and the resulting projected polar maps were used to estimate the radioactivity distribution within the left ventricular myocardium of the heart. Result: Mean ± SD for all summed scores is higher in FBP than CT-AC with SSS in FBP 32.60 ± 5.360, SRS FBP 31.60 ± 5.069 and SDS FBP 3.87 ± 3.159. Meanwhile for SSS in CT-AC is 28.27 ± 5.245, SRS CT-AC 27.20 ± 4.397 and SDS CT-AC 3.27 ± 2.449. There is statistically significant difference of SSS and SRS between FBP and CT-AC tested using Mann-Whitney test (p value = 0.002 for SSS and p-value = 0.001 for SRS). However, there is no statistically significant difference of SDS between FBP and CT-AC tested using Mann-Whitney test (p value = 0.633). Conclusion: Summed scores studies reconstructed with FBP are statistically not significantly different from AC. However, compensation for attenuation artifact is much better with iterative reconstruction CT-AC that FBP as CT-AC for SPECT MPI allows improved specificity of RCA territory compared with FBP reconstruction SPECT MPI. 2020 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/50988/1/Nur%20Syazana-24%20pages.pdf Zahir, Nur Syazana Mohd (2020) Semi-quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar MAPS. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | R Medicine Zahir, Nur Syazana Mohd Semi-quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar MAPS |
| title | Semi-quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar MAPS |
| title_full | Semi-quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar MAPS |
| title_fullStr | Semi-quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar MAPS |
| title_full_unstemmed | Semi-quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar MAPS |
| title_short | Semi-quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar MAPS |
| title_sort | semi quantitative assessment of myocardial perfusion abnormality on different reconstructed spect polar maps |
| topic | R Medicine |
| url | http://eprints.usm.my/50988/1/Nur%20Syazana-24%20pages.pdf |
| work_keys_str_mv | AT zahirnursyazanamohd semiquantitativeassessmentofmyocardialperfusionabnormalityondifferentreconstructedspectpolarmaps |