Effect Of Salt Concentration On Morphology And Mechanical Properties Of Polyurethane-Bioglass Composite Scaffold

The aim of tissue engineering is the fabrication of three-dimensional scaffolds that can be used for the reconstruction and regeneration of damaged tissues and organs. A broad variety of techniques have been developed to create either fibrous or porous scaffolds from polymers, metals, composite text...

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Main Author: Abidin, Muhamad Firdaus Zainal
Format: Monograph
Language:English
Published: Universiti Sains Malaysia 2017
Subjects:
Online Access:http://eprints.usm.my/52474/1/Effect%20Of%20Salt%20Concentration%20On%20Morphology%20And%20Mechanical%20Properties%20Of%20Polyurethane-Bioglass%20Composite%20Scaffold_Muhamad%20Firdaus%20%20Zainal%20Abidin_B1_2017.pdf
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author Abidin, Muhamad Firdaus Zainal
author_facet Abidin, Muhamad Firdaus Zainal
author_sort Abidin, Muhamad Firdaus Zainal
collection USM
description The aim of tissue engineering is the fabrication of three-dimensional scaffolds that can be used for the reconstruction and regeneration of damaged tissues and organs. A broad variety of techniques have been developed to create either fibrous or porous scaffolds from polymers, metals, composite textiles and ceramics. Nevertheless, the most promising materials are biodegradable polymers due to their comprehensive mechanical properties, ability to control the rate of degradation and similarities to natural tissue structures. In this study, porous bioactive glass (BG) reinforced polyurethane (PU) composite scaffolds with different salt ratio was fabricated by using salt leaching technique as this method does not involve any high temperature process that will affect the properties of the polymer. One of the factors that determine the properties of the scaffold is the porosity. Salt concentration is one of the parameters that influence the porosity. Various salt concentration were used with the aim of optimizing the pore network and to obtain the optimum mechanical properties of scaffolds. The chemical and physical properties of the fabricated porous scaffolds were examined by several characterization techniques including Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Fourier Transform Infrared Spectroscopy (FTIR), and compressive strength test. Composite scaffolds with low amount of porosity shows a better compressive strength and modulus. Overall, composite scaffolds with salt ratio 1:3 consists of pore which was homogeneously distributed and have the highest compressive strength.
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spelling usm.eprints-524742022-05-09T08:12:52Z http://eprints.usm.my/52474/ Effect Of Salt Concentration On Morphology And Mechanical Properties Of Polyurethane-Bioglass Composite Scaffold Abidin, Muhamad Firdaus Zainal T Technology TA401-492 Materials of engineering and construction. Mechanics of materials The aim of tissue engineering is the fabrication of three-dimensional scaffolds that can be used for the reconstruction and regeneration of damaged tissues and organs. A broad variety of techniques have been developed to create either fibrous or porous scaffolds from polymers, metals, composite textiles and ceramics. Nevertheless, the most promising materials are biodegradable polymers due to their comprehensive mechanical properties, ability to control the rate of degradation and similarities to natural tissue structures. In this study, porous bioactive glass (BG) reinforced polyurethane (PU) composite scaffolds with different salt ratio was fabricated by using salt leaching technique as this method does not involve any high temperature process that will affect the properties of the polymer. One of the factors that determine the properties of the scaffold is the porosity. Salt concentration is one of the parameters that influence the porosity. Various salt concentration were used with the aim of optimizing the pore network and to obtain the optimum mechanical properties of scaffolds. The chemical and physical properties of the fabricated porous scaffolds were examined by several characterization techniques including Scanning Electron Microscopy (SEM), Thermogravimetric Analysis (TGA), Fourier Transform Infrared Spectroscopy (FTIR), and compressive strength test. Composite scaffolds with low amount of porosity shows a better compressive strength and modulus. Overall, composite scaffolds with salt ratio 1:3 consists of pore which was homogeneously distributed and have the highest compressive strength. Universiti Sains Malaysia 2017-07-01 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/52474/1/Effect%20Of%20Salt%20Concentration%20On%20Morphology%20And%20Mechanical%20Properties%20Of%20Polyurethane-Bioglass%20Composite%20Scaffold_Muhamad%20Firdaus%20%20Zainal%20Abidin_B1_2017.pdf Abidin, Muhamad Firdaus Zainal (2017) Effect Of Salt Concentration On Morphology And Mechanical Properties Of Polyurethane-Bioglass Composite Scaffold. Project Report. Universiti Sains Malaysia, Pusat Pengajian Kejuruteraan Bahan Sumber Mineral. (Submitted)
spellingShingle T Technology
TA401-492 Materials of engineering and construction. Mechanics of materials
Abidin, Muhamad Firdaus Zainal
Effect Of Salt Concentration On Morphology And Mechanical Properties Of Polyurethane-Bioglass Composite Scaffold
title Effect Of Salt Concentration On Morphology And Mechanical Properties Of Polyurethane-Bioglass Composite Scaffold
title_full Effect Of Salt Concentration On Morphology And Mechanical Properties Of Polyurethane-Bioglass Composite Scaffold
title_fullStr Effect Of Salt Concentration On Morphology And Mechanical Properties Of Polyurethane-Bioglass Composite Scaffold
title_full_unstemmed Effect Of Salt Concentration On Morphology And Mechanical Properties Of Polyurethane-Bioglass Composite Scaffold
title_short Effect Of Salt Concentration On Morphology And Mechanical Properties Of Polyurethane-Bioglass Composite Scaffold
title_sort effect of salt concentration on morphology and mechanical properties of polyurethane bioglass composite scaffold
topic T Technology
TA401-492 Materials of engineering and construction. Mechanics of materials
url http://eprints.usm.my/52474/1/Effect%20Of%20Salt%20Concentration%20On%20Morphology%20And%20Mechanical%20Properties%20Of%20Polyurethane-Bioglass%20Composite%20Scaffold_Muhamad%20Firdaus%20%20Zainal%20Abidin_B1_2017.pdf
work_keys_str_mv AT abidinmuhamadfirdauszainal effectofsaltconcentrationonmorphologyandmechanicalpropertiesofpolyurethanebioglasscompositescaffold