Development Of A Multi-lumen Diameter Common Carotid Artery Wall-less Phantom And Blood Mimicking Fluids For Doppler Ultrasound

Flow phantoms with anatomically realistic geometry and high acoustic compatibility with real vessels are reliable tools in vascular ultrasound studies. A new common carotid artery (CCA) wall-less phantom with multi-lumen diameters has been presented to be used for ultrasound flow velocity studies us...

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Main Author: Kyermang Kyense, Dakok
Format: Thesis
Language:English
Published: 2021
Subjects:
Online Access:http://eprints.usm.my/52689/1/DAKOK%20KYERMANG%20KYENSE%20-%20TESIS24.pdf
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author Kyermang Kyense, Dakok
author_facet Kyermang Kyense, Dakok
author_sort Kyermang Kyense, Dakok
collection USM
description Flow phantoms with anatomically realistic geometry and high acoustic compatibility with real vessels are reliable tools in vascular ultrasound studies. A new common carotid artery (CCA) wall-less phantom with multi-lumen diameters has been presented to be used for ultrasound flow velocity studies using blood mimicking fluids (BMF) containing glucose and cholesterol. The phantom was constructed with 8 lumen diameters from 4.50 mm to 8.00 mm with a scanning depth of 7.5 mm, all within normal human carotid geometry. The tissue mimicking material (TMM) consists of konjac, carrageenan and gelatine as basic components mixed with other suitable components such as distilled water, aluminium oxide, potassium chloride, silicon carbide, glycerol and benzalkonium chloride. The BMF was prepared by mixing propylene glycol (PG), D(+)-glucose (DG) and poly (4-methystyrene) scatters in distilled water for the first BMF, followed by replacing the poly (4-methylstyrene) with cholesterol to form the second BMF. The constructed phantom was scanned using ultrasound machine to measure flow velocities, pulsatility index (PI) and resistivity index (RI) through the lumens and to test the effectiveness of the phantom. The phantom was found to have a speed of sound and attenuation of 1548.20±0.02 m/s and 0.35±0.02 dB/cm respectively at a frequency of 5 MHz. A very good BMF with glucose was produced having a density of 1.04±0.01 g/cm3, viscosity of 4.30±0.05 mpa.s, speed of sound of 1580.00±0.30 m/s and attenuation of 0.02±0.01 dB/cm at 5MHz
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spelling usm.eprints-526892022-05-31T16:30:46Z http://eprints.usm.my/52689/ Development Of A Multi-lumen Diameter Common Carotid Artery Wall-less Phantom And Blood Mimicking Fluids For Doppler Ultrasound Kyermang Kyense, Dakok QC1 Physics (General) Flow phantoms with anatomically realistic geometry and high acoustic compatibility with real vessels are reliable tools in vascular ultrasound studies. A new common carotid artery (CCA) wall-less phantom with multi-lumen diameters has been presented to be used for ultrasound flow velocity studies using blood mimicking fluids (BMF) containing glucose and cholesterol. The phantom was constructed with 8 lumen diameters from 4.50 mm to 8.00 mm with a scanning depth of 7.5 mm, all within normal human carotid geometry. The tissue mimicking material (TMM) consists of konjac, carrageenan and gelatine as basic components mixed with other suitable components such as distilled water, aluminium oxide, potassium chloride, silicon carbide, glycerol and benzalkonium chloride. The BMF was prepared by mixing propylene glycol (PG), D(+)-glucose (DG) and poly (4-methystyrene) scatters in distilled water for the first BMF, followed by replacing the poly (4-methylstyrene) with cholesterol to form the second BMF. The constructed phantom was scanned using ultrasound machine to measure flow velocities, pulsatility index (PI) and resistivity index (RI) through the lumens and to test the effectiveness of the phantom. The phantom was found to have a speed of sound and attenuation of 1548.20±0.02 m/s and 0.35±0.02 dB/cm respectively at a frequency of 5 MHz. A very good BMF with glucose was produced having a density of 1.04±0.01 g/cm3, viscosity of 4.30±0.05 mpa.s, speed of sound of 1580.00±0.30 m/s and attenuation of 0.02±0.01 dB/cm at 5MHz 2021-10 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/52689/1/DAKOK%20KYERMANG%20KYENSE%20-%20TESIS24.pdf Kyermang Kyense, Dakok (2021) Development Of A Multi-lumen Diameter Common Carotid Artery Wall-less Phantom And Blood Mimicking Fluids For Doppler Ultrasound. PhD thesis, Universiti Sains Malaysia.
spellingShingle QC1 Physics (General)
Kyermang Kyense, Dakok
Development Of A Multi-lumen Diameter Common Carotid Artery Wall-less Phantom And Blood Mimicking Fluids For Doppler Ultrasound
title Development Of A Multi-lumen Diameter Common Carotid Artery Wall-less Phantom And Blood Mimicking Fluids For Doppler Ultrasound
title_full Development Of A Multi-lumen Diameter Common Carotid Artery Wall-less Phantom And Blood Mimicking Fluids For Doppler Ultrasound
title_fullStr Development Of A Multi-lumen Diameter Common Carotid Artery Wall-less Phantom And Blood Mimicking Fluids For Doppler Ultrasound
title_full_unstemmed Development Of A Multi-lumen Diameter Common Carotid Artery Wall-less Phantom And Blood Mimicking Fluids For Doppler Ultrasound
title_short Development Of A Multi-lumen Diameter Common Carotid Artery Wall-less Phantom And Blood Mimicking Fluids For Doppler Ultrasound
title_sort development of a multi lumen diameter common carotid artery wall less phantom and blood mimicking fluids for doppler ultrasound
topic QC1 Physics (General)
url http://eprints.usm.my/52689/1/DAKOK%20KYERMANG%20KYENSE%20-%20TESIS24.pdf
work_keys_str_mv AT kyermangkyensedakok developmentofamultilumendiametercommoncarotidarterywalllessphantomandbloodmimickingfluidsfordopplerultrasound