Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats
In this study, the protective effect of xanthone enriched fraction of G. mangostana (XEFGM) and α-MG were evaluated in an animal model of VaD induced by chronic cerebral hypoperfusion also known as- two vessel occlusion (2VO). In the first part of this study, XEFGM (25, 50, and 100 mg/kg) and α-MG (...
| Main Author: | |
|---|---|
| Format: | Thesis |
| Language: | English |
| Published: |
2021
|
| Subjects: | |
| Online Access: | http://eprints.usm.my/53333/1/TIANG%20NING%20-%20TESIS.pdf%20cut.pdf |
| _version_ | 1797012997330173952 |
|---|---|
| author | Tiang, Ning |
| author_facet | Tiang, Ning |
| author_sort | Tiang, Ning |
| collection | USM |
| description | In this study, the protective effect of xanthone enriched fraction of G. mangostana (XEFGM) and α-MG were evaluated in an animal model of VaD induced by chronic cerebral hypoperfusion also known as- two vessel occlusion (2VO). In the first part of this study, XEFGM (25, 50, and 100 mg/kg) and α-MG (25 and 50 mg/kg) were administrated to 2VO rats and the rats were then subjected to behavioral test for learning and reference memory evaluation. The result suggested that, 50 mg/kg of α-MG treated 2VO significantly improved spatial learning and reference memory in Morris water maze test. |
| first_indexed | 2024-03-06T15:55:50Z |
| format | Thesis |
| id | usm.eprints-53333 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T15:55:50Z |
| publishDate | 2021 |
| record_format | dspace |
| spelling | usm.eprints-533332022-07-13T07:29:18Z http://eprints.usm.my/53333/ Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats Tiang, Ning RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry In this study, the protective effect of xanthone enriched fraction of G. mangostana (XEFGM) and α-MG were evaluated in an animal model of VaD induced by chronic cerebral hypoperfusion also known as- two vessel occlusion (2VO). In the first part of this study, XEFGM (25, 50, and 100 mg/kg) and α-MG (25 and 50 mg/kg) were administrated to 2VO rats and the rats were then subjected to behavioral test for learning and reference memory evaluation. The result suggested that, 50 mg/kg of α-MG treated 2VO significantly improved spatial learning and reference memory in Morris water maze test. 2021-02 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/53333/1/TIANG%20NING%20-%20TESIS.pdf%20cut.pdf Tiang, Ning (2021) Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats. Masters thesis, Universiti Sains Malaysia. |
| spellingShingle | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry Tiang, Ning Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats |
| title | Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats |
| title_full | Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats |
| title_fullStr | Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats |
| title_full_unstemmed | Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats |
| title_short | Neuroprotective Effects Of Xanthone-Enriched Fraction Garcinia Mangostana And Alpha-Mangostin In Chronic Cerebral Hypoperfusion Rats |
| title_sort | neuroprotective effects of xanthone enriched fraction garcinia mangostana and alpha mangostin in chronic cerebral hypoperfusion rats |
| topic | RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| url | http://eprints.usm.my/53333/1/TIANG%20NING%20-%20TESIS.pdf%20cut.pdf |
| work_keys_str_mv | AT tiangning neuroprotectiveeffectsofxanthoneenrichedfractiongarciniamangostanaandalphamangostininchroniccerebralhypoperfusionrats |