The effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer
Purpose: To identify the effect of dose calculation algorithms on the Normal Tissue Complication Probability values of thoracic cancer. Materials and Methods: NTCP values from BIOPLAN software is calculated based on standard DVH data. Dose distributions of treatment plans are calculated by usin...
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| Format: | Monograph |
| Language: | English |
| Published: |
Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia
2015
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| Subjects: | |
| Online Access: | http://eprints.usm.my/57934/1/NOOR%20ASHIKIN%20BINTI%20AHMAD-24%20pages.pdf |
| _version_ | 1797013960394801152 |
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| author | Ahmad, Noor Ashikin |
| author_facet | Ahmad, Noor Ashikin |
| author_sort | Ahmad, Noor Ashikin |
| collection | USM |
| description | Purpose: To identify the effect of dose calculation algorithms on the Normal Tissue
Complication Probability values of thoracic cancer.
Materials and Methods: NTCP
values from BIOPLAN software is calculated based on standard DVH data. Dose
distributions of treatment plans are calculated by using two different algorithms of
Oncentra Masterplan (OMP) treatment planning system (TPS) which are Collapse Cone
and Pencil Beam. Four treatment plans are created and DVHs are evaluated based on
criteria of acceptance level. NTCP values for thorax plan one and two are evaluated by
using different algorithm.
Results: The coverage of the target volume for all treatment
plans has achieved the desired isodose for at least 90% of isodose at 1 00% of volume.
Collapsed cone shows better calculation in three beam but pencil beam is better in 5
beams calculation. The NTCP values of the LKB model are slightly higher than RS
model for both cases even though using different kind of algorithm.
Conclusions: There
is no difference between pencil beam and collapsed cone algorithms in term of NTCP
values. NTCP values are due to physical and biological effects. Mathematically, both
treatment plans have higher probability to develop the complication but the numbers in
this paper are not wholly based on clinical or even experimental data. It may due to
patient-related factors, patient history or the modalities used in treatment delivery. |
| first_indexed | 2024-03-06T16:09:26Z |
| format | Monograph |
| id | usm.eprints-57934 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2024-03-06T16:09:26Z |
| publishDate | 2015 |
| publisher | Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia |
| record_format | dspace |
| spelling | usm.eprints-579342023-04-12T04:32:35Z http://eprints.usm.my/57934/ The effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer Ahmad, Noor Ashikin RC254-282 Neoplasms. Tumors. Oncology (including Cancer) Purpose: To identify the effect of dose calculation algorithms on the Normal Tissue Complication Probability values of thoracic cancer. Materials and Methods: NTCP values from BIOPLAN software is calculated based on standard DVH data. Dose distributions of treatment plans are calculated by using two different algorithms of Oncentra Masterplan (OMP) treatment planning system (TPS) which are Collapse Cone and Pencil Beam. Four treatment plans are created and DVHs are evaluated based on criteria of acceptance level. NTCP values for thorax plan one and two are evaluated by using different algorithm. Results: The coverage of the target volume for all treatment plans has achieved the desired isodose for at least 90% of isodose at 1 00% of volume. Collapsed cone shows better calculation in three beam but pencil beam is better in 5 beams calculation. The NTCP values of the LKB model are slightly higher than RS model for both cases even though using different kind of algorithm. Conclusions: There is no difference between pencil beam and collapsed cone algorithms in term of NTCP values. NTCP values are due to physical and biological effects. Mathematically, both treatment plans have higher probability to develop the complication but the numbers in this paper are not wholly based on clinical or even experimental data. It may due to patient-related factors, patient history or the modalities used in treatment delivery. Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia 2015-06 Monograph NonPeerReviewed application/pdf en http://eprints.usm.my/57934/1/NOOR%20ASHIKIN%20BINTI%20AHMAD-24%20pages.pdf Ahmad, Noor Ashikin (2015) The effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer. Project Report. Pusat Pengajian Sains Perubatan, Universiti Sains Malaysia. (Submitted) |
| spellingShingle | RC254-282 Neoplasms. Tumors. Oncology (including Cancer) Ahmad, Noor Ashikin The effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer |
| title | The effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer |
| title_full | The effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer |
| title_fullStr | The effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer |
| title_full_unstemmed | The effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer |
| title_short | The effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer |
| title_sort | effect of dose calculation algorithms on the normal tissue complication probability values of thoracic cancer |
| topic | RC254-282 Neoplasms. Tumors. Oncology (including Cancer) |
| url | http://eprints.usm.my/57934/1/NOOR%20ASHIKIN%20BINTI%20AHMAD-24%20pages.pdf |
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