Isolation And Characterization Of Aptamers Against Leptospira Lipl32

In this study, both DNA and RNA aptamers were developed against LipL32. LepRapt-11 was shown to be the most potent RNA aptamer, with dissociation constant and limit of detection of 350 ± 47.45 and 100 nM as determined by direct Enzyme-linked Aptasorbent Assay (ELASA), respectively.

Bibliographic Details
Main Author: Yeoh, Tzi Shien
Format: Thesis
Language:English
Published: 2023
Subjects:
Online Access:http://eprints.usm.my/60592/1/Pages%20from%20YEOH%20TZI%20SHIEN%20-%20TESIS.pdf
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author Yeoh, Tzi Shien
author_facet Yeoh, Tzi Shien
author_sort Yeoh, Tzi Shien
collection USM
description In this study, both DNA and RNA aptamers were developed against LipL32. LepRapt-11 was shown to be the most potent RNA aptamer, with dissociation constant and limit of detection of 350 ± 47.45 and 100 nM as determined by direct Enzyme-linked Aptasorbent Assay (ELASA), respectively.
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spelling usm.eprints-605922024-05-08T07:21:08Z http://eprints.usm.my/60592/ Isolation And Characterization Of Aptamers Against Leptospira Lipl32 Yeoh, Tzi Shien R5-920 Medicine (General) In this study, both DNA and RNA aptamers were developed against LipL32. LepRapt-11 was shown to be the most potent RNA aptamer, with dissociation constant and limit of detection of 350 ± 47.45 and 100 nM as determined by direct Enzyme-linked Aptasorbent Assay (ELASA), respectively. 2023-06 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/60592/1/Pages%20from%20YEOH%20TZI%20SHIEN%20-%20TESIS.pdf Yeoh, Tzi Shien (2023) Isolation And Characterization Of Aptamers Against Leptospira Lipl32. PhD thesis, Universiti Sains Malaysia.
spellingShingle R5-920 Medicine (General)
Yeoh, Tzi Shien
Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_full Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_fullStr Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_full_unstemmed Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_short Isolation And Characterization Of Aptamers Against Leptospira Lipl32
title_sort isolation and characterization of aptamers against leptospira lipl32
topic R5-920 Medicine (General)
url http://eprints.usm.my/60592/1/Pages%20from%20YEOH%20TZI%20SHIEN%20-%20TESIS.pdf
work_keys_str_mv AT yeohtzishien isolationandcharacterizationofaptamersagainstleptospiralipl32