Isolation And Characterization Of Aptamers Against Leptospira Lipl32
In this study, both DNA and RNA aptamers were developed against LipL32. LepRapt-11 was shown to be the most potent RNA aptamer, with dissociation constant and limit of detection of 350 ± 47.45 and 100 nM as determined by direct Enzyme-linked Aptasorbent Assay (ELASA), respectively.
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Format: | Thesis |
Language: | English |
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2023
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Online Access: | http://eprints.usm.my/60592/1/Pages%20from%20YEOH%20TZI%20SHIEN%20-%20TESIS.pdf |
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author | Yeoh, Tzi Shien |
author_facet | Yeoh, Tzi Shien |
author_sort | Yeoh, Tzi Shien |
collection | USM |
description | In this study, both DNA and RNA aptamers were developed against LipL32. LepRapt-11 was shown to be the most potent RNA aptamer, with dissociation constant and limit of detection of 350 ± 47.45 and 100 nM as determined by direct Enzyme-linked Aptasorbent Assay (ELASA), respectively. |
first_indexed | 2024-09-25T03:56:41Z |
format | Thesis |
id | usm.eprints-60592 |
institution | Universiti Sains Malaysia |
language | English |
last_indexed | 2024-09-25T03:56:41Z |
publishDate | 2023 |
record_format | dspace |
spelling | usm.eprints-605922024-05-08T07:21:08Z http://eprints.usm.my/60592/ Isolation And Characterization Of Aptamers Against Leptospira Lipl32 Yeoh, Tzi Shien R5-920 Medicine (General) In this study, both DNA and RNA aptamers were developed against LipL32. LepRapt-11 was shown to be the most potent RNA aptamer, with dissociation constant and limit of detection of 350 ± 47.45 and 100 nM as determined by direct Enzyme-linked Aptasorbent Assay (ELASA), respectively. 2023-06 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/60592/1/Pages%20from%20YEOH%20TZI%20SHIEN%20-%20TESIS.pdf Yeoh, Tzi Shien (2023) Isolation And Characterization Of Aptamers Against Leptospira Lipl32. PhD thesis, Universiti Sains Malaysia. |
spellingShingle | R5-920 Medicine (General) Yeoh, Tzi Shien Isolation And Characterization Of Aptamers Against Leptospira Lipl32 |
title | Isolation And Characterization Of Aptamers Against Leptospira Lipl32 |
title_full | Isolation And Characterization Of Aptamers Against Leptospira Lipl32 |
title_fullStr | Isolation And Characterization Of Aptamers Against Leptospira Lipl32 |
title_full_unstemmed | Isolation And Characterization Of Aptamers Against Leptospira Lipl32 |
title_short | Isolation And Characterization Of Aptamers Against Leptospira Lipl32 |
title_sort | isolation and characterization of aptamers against leptospira lipl32 |
topic | R5-920 Medicine (General) |
url | http://eprints.usm.my/60592/1/Pages%20from%20YEOH%20TZI%20SHIEN%20-%20TESIS.pdf |
work_keys_str_mv | AT yeohtzishien isolationandcharacterizationofaptamersagainstleptospiralipl32 |