Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor

Sarcopenia is a condition characterized by loss of skeletal muscle mass and function. Although it is primarily a disease of the elderly, its development may be associated with conditions that are not exclusively seen in elderly population. Hence, it is important to identify the prevalence of sarcope...

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Main Author: Moorthy, Shantasaroopini Sathia
Format: Thesis
Language:English
Published: 2023
Subjects:
Online Access:http://eprints.usm.my/61330/1/24%20Pages%20from%20SHANTASAROOPINI%20AP%20SATHIA%20MOORTHY.pdf
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author Moorthy, Shantasaroopini Sathia
author_facet Moorthy, Shantasaroopini Sathia
author_sort Moorthy, Shantasaroopini Sathia
collection USM
description Sarcopenia is a condition characterized by loss of skeletal muscle mass and function. Although it is primarily a disease of the elderly, its development may be associated with conditions that are not exclusively seen in elderly population. Hence, it is important to identify the prevalence of sarcopenia in chronic kidney disease population and its associated risk factors in pre-dialysis patients with chronic kidney disease. This eight months cross-sectional study was conducted on 250 pre-dialysis patients with chronic kidney disease aged 18 years or older who attended the out-patient Renal Clinic at Hospital Pakar Sultanah Fatimah Muar Johor. By using the diagnostic methods proposed by AWGS, sarcopenia was detected in 5.2% of pre-dialysis patients with CKD, with CKD stage 3-5 accounting for 0.4%, 0.8%, and 4% respectively. Multiple logistic regression models revealed that sarcopenia was associated with age (AOR: 0.966, 95% CI: 0.801-1.164), body mass index (BMI) (AOR: 0.390, 95% CI: 0.166-0.912), presence of chronic illness (AOR: 0.529, 95% CI: 0.023-12.237), MBI score (AOR: 0.644, 95% CI: 0.470-0.884, and serum albumin (AOR: 0.813, 95% CI: 0.526-1.257).
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spelling usm.eprints-613302024-10-18T00:56:26Z http://eprints.usm.my/61330/ Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor Moorthy, Shantasaroopini Sathia RS1-441 Pharmacy and materia medica Sarcopenia is a condition characterized by loss of skeletal muscle mass and function. Although it is primarily a disease of the elderly, its development may be associated with conditions that are not exclusively seen in elderly population. Hence, it is important to identify the prevalence of sarcopenia in chronic kidney disease population and its associated risk factors in pre-dialysis patients with chronic kidney disease. This eight months cross-sectional study was conducted on 250 pre-dialysis patients with chronic kidney disease aged 18 years or older who attended the out-patient Renal Clinic at Hospital Pakar Sultanah Fatimah Muar Johor. By using the diagnostic methods proposed by AWGS, sarcopenia was detected in 5.2% of pre-dialysis patients with CKD, with CKD stage 3-5 accounting for 0.4%, 0.8%, and 4% respectively. Multiple logistic regression models revealed that sarcopenia was associated with age (AOR: 0.966, 95% CI: 0.801-1.164), body mass index (BMI) (AOR: 0.390, 95% CI: 0.166-0.912), presence of chronic illness (AOR: 0.529, 95% CI: 0.023-12.237), MBI score (AOR: 0.644, 95% CI: 0.470-0.884, and serum albumin (AOR: 0.813, 95% CI: 0.526-1.257). 2023-09 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/61330/1/24%20Pages%20from%20SHANTASAROOPINI%20AP%20SATHIA%20MOORTHY.pdf Moorthy, Shantasaroopini Sathia (2023) Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor. Masters thesis, Perpustakaan Hamzah Sendut.
spellingShingle RS1-441 Pharmacy and materia medica
Moorthy, Shantasaroopini Sathia
Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_full Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_fullStr Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_full_unstemmed Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_short Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_sort prevalence and factors associated with sarcopenia in outpatient pre dialysis patients in a tertiary care centre in johor
topic RS1-441 Pharmacy and materia medica
url http://eprints.usm.my/61330/1/24%20Pages%20from%20SHANTASAROOPINI%20AP%20SATHIA%20MOORTHY.pdf
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