Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds
The aim of this study is to fabricate a new material by combining hydrophobic and hydrophilic materials. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) has adequate flexibility for medical applications, however, its lack of hydrophilic properties limits its applications in this field. Therefore, the...
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Format: | Thesis |
Language: | English |
Published: |
2019
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Online Access: | http://eprints.usm.my/61965/1/Fabrication%20and%20characterization%20of%20poly%20cut.pdf |
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author | Mat Junoh, Azuraini |
author_facet | Mat Junoh, Azuraini |
author_sort | Mat Junoh, Azuraini |
collection | USM |
description | The aim of this study is to fabricate a new material by combining hydrophobic and hydrophilic materials. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) has adequate flexibility for medical applications, however, its lack of hydrophilic
properties limits its applications in this field. Therefore, the P(3HB-co-4HB) polymer was blended with gelatin using two different techniques; freeze-drying and electrospinning. The former technique can produce porous scaffolds by manipulating
various parameters including 4HB monomer content, gelatin concentrations, and total
weight of the scaffolds. The surface morphology results of the blend scaffolds at 27
mol%4HB and 50 mol%4HB have high porosity but the porosity of the blend scaffold decreased at 82 mol%4HB. |
first_indexed | 2025-03-06T09:55:57Z |
format | Thesis |
id | usm.eprints-61965 |
institution | Universiti Sains Malaysia |
language | English |
last_indexed | 2025-03-06T09:55:57Z |
publishDate | 2019 |
record_format | dspace |
spelling | usm.eprints-619652025-03-04T04:24:04Z http://eprints.usm.my/61965/ Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds Mat Junoh, Azuraini R856-857 Biomedical engineering. Electronics. Instrumentation The aim of this study is to fabricate a new material by combining hydrophobic and hydrophilic materials. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) has adequate flexibility for medical applications, however, its lack of hydrophilic properties limits its applications in this field. Therefore, the P(3HB-co-4HB) polymer was blended with gelatin using two different techniques; freeze-drying and electrospinning. The former technique can produce porous scaffolds by manipulating various parameters including 4HB monomer content, gelatin concentrations, and total weight of the scaffolds. The surface morphology results of the blend scaffolds at 27 mol%4HB and 50 mol%4HB have high porosity but the porosity of the blend scaffold decreased at 82 mol%4HB. 2019-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/61965/1/Fabrication%20and%20characterization%20of%20poly%20cut.pdf Mat Junoh, Azuraini (2019) Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds. Masters thesis, Universiti Sains Malaysia. |
spellingShingle | R856-857 Biomedical engineering. Electronics. Instrumentation Mat Junoh, Azuraini Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds |
title | Fabrication And Characterization Of
Poly(3-Hydroxybutyrate-Co-4-
Hydroxybutyrate)/Gelatin Blend
Scaffolds |
title_full | Fabrication And Characterization Of
Poly(3-Hydroxybutyrate-Co-4-
Hydroxybutyrate)/Gelatin Blend
Scaffolds |
title_fullStr | Fabrication And Characterization Of
Poly(3-Hydroxybutyrate-Co-4-
Hydroxybutyrate)/Gelatin Blend
Scaffolds |
title_full_unstemmed | Fabrication And Characterization Of
Poly(3-Hydroxybutyrate-Co-4-
Hydroxybutyrate)/Gelatin Blend
Scaffolds |
title_short | Fabrication And Characterization Of
Poly(3-Hydroxybutyrate-Co-4-
Hydroxybutyrate)/Gelatin Blend
Scaffolds |
title_sort | fabrication and characterization of poly 3 hydroxybutyrate co 4 hydroxybutyrate gelatin blend scaffolds |
topic | R856-857 Biomedical engineering. Electronics. Instrumentation |
url | http://eprints.usm.my/61965/1/Fabrication%20and%20characterization%20of%20poly%20cut.pdf |
work_keys_str_mv | AT matjunohazuraini fabricationandcharacterizationofpoly3hydroxybutyrateco4hydroxybutyrategelatinblendscaffolds |