Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds

The aim of this study is to fabricate a new material by combining hydrophobic and hydrophilic materials. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) has adequate flexibility for medical applications, however, its lack of hydrophilic properties limits its applications in this field. Therefore, the...

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Main Author: Mat Junoh, Azuraini
Format: Thesis
Language:English
Published: 2019
Subjects:
Online Access:http://eprints.usm.my/61965/1/Fabrication%20and%20characterization%20of%20poly%20cut.pdf
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author Mat Junoh, Azuraini
author_facet Mat Junoh, Azuraini
author_sort Mat Junoh, Azuraini
collection USM
description The aim of this study is to fabricate a new material by combining hydrophobic and hydrophilic materials. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) has adequate flexibility for medical applications, however, its lack of hydrophilic properties limits its applications in this field. Therefore, the P(3HB-co-4HB) polymer was blended with gelatin using two different techniques; freeze-drying and electrospinning. The former technique can produce porous scaffolds by manipulating various parameters including 4HB monomer content, gelatin concentrations, and total weight of the scaffolds. The surface morphology results of the blend scaffolds at 27 mol%4HB and 50 mol%4HB have high porosity but the porosity of the blend scaffold decreased at 82 mol%4HB.
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spelling usm.eprints-619652025-03-04T04:24:04Z http://eprints.usm.my/61965/ Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds Mat Junoh, Azuraini R856-857 Biomedical engineering. Electronics. Instrumentation The aim of this study is to fabricate a new material by combining hydrophobic and hydrophilic materials. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) has adequate flexibility for medical applications, however, its lack of hydrophilic properties limits its applications in this field. Therefore, the P(3HB-co-4HB) polymer was blended with gelatin using two different techniques; freeze-drying and electrospinning. The former technique can produce porous scaffolds by manipulating various parameters including 4HB monomer content, gelatin concentrations, and total weight of the scaffolds. The surface morphology results of the blend scaffolds at 27 mol%4HB and 50 mol%4HB have high porosity but the porosity of the blend scaffold decreased at 82 mol%4HB. 2019-07 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/61965/1/Fabrication%20and%20characterization%20of%20poly%20cut.pdf Mat Junoh, Azuraini (2019) Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds. Masters thesis, Universiti Sains Malaysia.
spellingShingle R856-857 Biomedical engineering. Electronics. Instrumentation
Mat Junoh, Azuraini
Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds
title Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds
title_full Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds
title_fullStr Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds
title_full_unstemmed Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds
title_short Fabrication And Characterization Of Poly(3-Hydroxybutyrate-Co-4- Hydroxybutyrate)/Gelatin Blend Scaffolds
title_sort fabrication and characterization of poly 3 hydroxybutyrate co 4 hydroxybutyrate gelatin blend scaffolds
topic R856-857 Biomedical engineering. Electronics. Instrumentation
url http://eprints.usm.my/61965/1/Fabrication%20and%20characterization%20of%20poly%20cut.pdf
work_keys_str_mv AT matjunohazuraini fabricationandcharacterizationofpoly3hydroxybutyrateco4hydroxybutyrategelatinblendscaffolds