Comparative study of micromixers for laminar blood mixing

Miniaturization is the trend in analytical chemistry and life science. It has been emerging into the research field of microfluidics in the application of LOC. The application is used for biochemistry analysis and require a rapid mixing in small area. Due to laminar flow (Reynold Number < 1) p...

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Main Author: Khalid, Khairul Nadiah
Format: Thesis
Language:English
English
English
Published: 2013
Subjects:
Online Access:http://eprints.uthm.edu.my/6658/1/24p%20KHAIRUL%20NADIAH%20KHALID.pdf
http://eprints.uthm.edu.my/6658/2/KHAIRUL%20NADIAH%20KHALID%20COPYRIGHT%20DECLARATION.pdf
http://eprints.uthm.edu.my/6658/3/KHAIRUL%20NADIAH%20KHALID%20WATERMARK.pdf
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author Khalid, Khairul Nadiah
author_facet Khalid, Khairul Nadiah
author_sort Khalid, Khairul Nadiah
collection UTHM
description Miniaturization is the trend in analytical chemistry and life science. It has been emerging into the research field of microfluidics in the application of LOC. The application is used for biochemistry analysis and require a rapid mixing in small area. Due to laminar flow (Reynold Number < 1) passive micromixer is the best method in fluids mixing. Passive micromixer also depend on the channel geometry for mixing effectiveness. In this study, four different micromixers were evaluated based on the baseline control Y-micromixer. The micromixers are internal rib micromixer, patterned grooves micromixer, obstruction micromixer and slanted rib micromixer. These micromixer has 1000μm channel length, 150μm inlet length, 90o between inlets ports, width and depth are 40μm each. The fluids used for mixing were blood which has 1.0 × 10-6 kg/μms of viscosity and toluene which has low viscosity than blood (0.664 × 10-9 kg/μms). The fluids used to evaluate the differences in term of their visual performance based image’s standard deviation by plotting the graph and mixing efficiency by calculation. Based on these evaluations, the slanted rib micromixer is the best micromixer design with the highest mixing efficiency of 99.85% at the outlet of the channel.
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spelling uthm.eprints-66582022-03-14T01:36:21Z http://eprints.uthm.edu.my/6658/ Comparative study of micromixers for laminar blood mixing Khalid, Khairul Nadiah TA164 Bioengineering Miniaturization is the trend in analytical chemistry and life science. It has been emerging into the research field of microfluidics in the application of LOC. The application is used for biochemistry analysis and require a rapid mixing in small area. Due to laminar flow (Reynold Number < 1) passive micromixer is the best method in fluids mixing. Passive micromixer also depend on the channel geometry for mixing effectiveness. In this study, four different micromixers were evaluated based on the baseline control Y-micromixer. The micromixers are internal rib micromixer, patterned grooves micromixer, obstruction micromixer and slanted rib micromixer. These micromixer has 1000μm channel length, 150μm inlet length, 90o between inlets ports, width and depth are 40μm each. The fluids used for mixing were blood which has 1.0 × 10-6 kg/μms of viscosity and toluene which has low viscosity than blood (0.664 × 10-9 kg/μms). The fluids used to evaluate the differences in term of their visual performance based image’s standard deviation by plotting the graph and mixing efficiency by calculation. Based on these evaluations, the slanted rib micromixer is the best micromixer design with the highest mixing efficiency of 99.85% at the outlet of the channel. 2013-07 Thesis NonPeerReviewed text en http://eprints.uthm.edu.my/6658/1/24p%20KHAIRUL%20NADIAH%20KHALID.pdf text en http://eprints.uthm.edu.my/6658/2/KHAIRUL%20NADIAH%20KHALID%20COPYRIGHT%20DECLARATION.pdf text en http://eprints.uthm.edu.my/6658/3/KHAIRUL%20NADIAH%20KHALID%20WATERMARK.pdf Khalid, Khairul Nadiah (2013) Comparative study of micromixers for laminar blood mixing. Masters thesis, Universiti Tun Hussein Malaysia.
spellingShingle TA164 Bioengineering
Khalid, Khairul Nadiah
Comparative study of micromixers for laminar blood mixing
title Comparative study of micromixers for laminar blood mixing
title_full Comparative study of micromixers for laminar blood mixing
title_fullStr Comparative study of micromixers for laminar blood mixing
title_full_unstemmed Comparative study of micromixers for laminar blood mixing
title_short Comparative study of micromixers for laminar blood mixing
title_sort comparative study of micromixers for laminar blood mixing
topic TA164 Bioengineering
url http://eprints.uthm.edu.my/6658/1/24p%20KHAIRUL%20NADIAH%20KHALID.pdf
http://eprints.uthm.edu.my/6658/2/KHAIRUL%20NADIAH%20KHALID%20COPYRIGHT%20DECLARATION.pdf
http://eprints.uthm.edu.my/6658/3/KHAIRUL%20NADIAH%20KHALID%20WATERMARK.pdf
work_keys_str_mv AT khalidkhairulnadiah comparativestudyofmicromixersforlaminarbloodmixing