Electrospinning of aligned nanofibers for biomedical application using a rotating drum collector
Both random and aligned collagen fibers exist in extracellular matrix. The alignment of fiber in tissue engineering scaffolds can affect the cell morphology. Therefore, knowledge in the control of microstructure alignment in electrospun scaffolds is crucial. In this study, a rotating collector...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Microscopy Society of Malaysia (MSM)
2021
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| Subjects: | |
| Online Access: | http://eprints.uthm.edu.my/6866/1/J13769_d8d30819aef844cca1764f56c42fe173.pdf |
| _version_ | 1825710268555984896 |
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| author | Wen, Jun Ham Ching, Theng Koh |
| author_facet | Wen, Jun Ham Ching, Theng Koh |
| author_sort | Wen, Jun Ham |
| collection | UTHM |
| description | Both random and aligned collagen fibers exist in extracellular matrix. The
alignment of fiber in tissue engineering scaffolds can affect the cell morphology. Therefore,
knowledge in the control of microstructure alignment in electrospun scaffolds is crucial. In
this study, a rotating collector drum was designed and fabricated to collect aligned gelatin
fibers using an electrospinning technique. The speed of the fabricated rotating drum collector
was adjustable and controlled at 1000 rpm, 2000 rpm, and 3000 rpm. Electrospun scaffolds
having aligned fibers were successfully produced using the rotating drum at 3000 rpm and
compared with random nanofibers collected with the static plate. The speed of the rotating
drum collector increased the alignment of the fibers and had little influence on fiber diameter.
The results provide process parameters for the fabrication of aligned gelatin fibers. |
| first_indexed | 2024-03-05T21:55:02Z |
| format | Article |
| id | uthm.eprints-6866 |
| institution | Universiti Tun Hussein Onn Malaysia |
| language | English |
| last_indexed | 2024-03-05T21:55:02Z |
| publishDate | 2021 |
| publisher | Microscopy Society of Malaysia (MSM) |
| record_format | dspace |
| spelling | uthm.eprints-68662022-04-05T06:45:22Z http://eprints.uthm.edu.my/6866/ Electrospinning of aligned nanofibers for biomedical application using a rotating drum collector Wen, Jun Ham Ching, Theng Koh TP248.13-248.65 Biotechnology Both random and aligned collagen fibers exist in extracellular matrix. The alignment of fiber in tissue engineering scaffolds can affect the cell morphology. Therefore, knowledge in the control of microstructure alignment in electrospun scaffolds is crucial. In this study, a rotating collector drum was designed and fabricated to collect aligned gelatin fibers using an electrospinning technique. The speed of the fabricated rotating drum collector was adjustable and controlled at 1000 rpm, 2000 rpm, and 3000 rpm. Electrospun scaffolds having aligned fibers were successfully produced using the rotating drum at 3000 rpm and compared with random nanofibers collected with the static plate. The speed of the rotating drum collector increased the alignment of the fibers and had little influence on fiber diameter. The results provide process parameters for the fabrication of aligned gelatin fibers. Microscopy Society of Malaysia (MSM) 2021 Article PeerReviewed text en http://eprints.uthm.edu.my/6866/1/J13769_d8d30819aef844cca1764f56c42fe173.pdf Wen, Jun Ham and Ching, Theng Koh (2021) Electrospinning of aligned nanofibers for biomedical application using a rotating drum collector. Malaysian Journal of Microscopy, 17 (2). pp. 154-161. ISSN 1823-7010 |
| spellingShingle | TP248.13-248.65 Biotechnology Wen, Jun Ham Ching, Theng Koh Electrospinning of aligned nanofibers for biomedical application using a rotating drum collector |
| title | Electrospinning of aligned nanofibers for biomedical application using a rotating drum collector |
| title_full | Electrospinning of aligned nanofibers for biomedical application using a rotating drum collector |
| title_fullStr | Electrospinning of aligned nanofibers for biomedical application using a rotating drum collector |
| title_full_unstemmed | Electrospinning of aligned nanofibers for biomedical application using a rotating drum collector |
| title_short | Electrospinning of aligned nanofibers for biomedical application using a rotating drum collector |
| title_sort | electrospinning of aligned nanofibers for biomedical application using a rotating drum collector |
| topic | TP248.13-248.65 Biotechnology |
| url | http://eprints.uthm.edu.my/6866/1/J13769_d8d30819aef844cca1764f56c42fe173.pdf |
| work_keys_str_mv | AT wenjunham electrospinningofalignednanofibersforbiomedicalapplicationusingarotatingdrumcollector AT chingthengkoh electrospinningofalignednanofibersforbiomedicalapplicationusingarotatingdrumcollector |