Photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin: a preliminary investigation
Tissue oxygen monitoring systems, such as pulse oximeter, is unreliable in patients with compromised microcirculation. Modern imaging modalities such as Magnetic Resonance Imaging (MRI) offer good diagnostic accuracy at the expense of increased cost and complexity in their operations. This p...
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Teknologi Malaysia Press
2022
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| Subjects: | |
| Online Access: | http://eprints.uthm.edu.my/7596/1/J14479_d64bd9f49a6c20d2038b05bf7136b1ff.pdf |
| _version_ | 1796869592073633792 |
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| author | Hui, Ling Chua Huong, Audrey |
| author_facet | Hui, Ling Chua Huong, Audrey |
| author_sort | Hui, Ling Chua |
| collection | UTHM |
| description | Tissue oxygen monitoring systems, such as pulse oximeter, is
unreliable in patients with compromised microcirculation. Modern
imaging modalities such as Magnetic Resonance Imaging (MRI)
offer good diagnostic accuracy at the expense of increased cost
and complexity in their operations. This paper studies the use of
photoacoustic (PA) phase change as a predictor of skin tissue
oxygen levels. We used EPOCH 650 ultrasonic flaw detector with a
longitudinal transducer for measurement of PA waves. This pilot
study was conducted on six human subjects. The produced
ultrasonic waves were collected from their anterior left arm under
three experimental conditions, namely at rest, venous and arterial
blood flow occlusions, for determination of hemoglobin absorption
dependent phase change in tissue. The overall mean and standard
deviation (STDEV) of phase angles for at rest condition are
calculated as 1.43 ± 0.06 radians (rads). Higher phase angles are
determined for diastolic and systolic occlusion pressures given by
1.69 ± 0.05 rads and 2.09 ± 0.06 rads, respectively. This work
concluded that the feasibility of our PA system to monitor changes
in tissue oxygen performance renders it a promising alternative for
portable assessment and measurement of oxygen concentration
within microcirculation environment. |
| first_indexed | 2024-03-05T21:57:12Z |
| format | Article |
| id | uthm.eprints-7596 |
| institution | Universiti Tun Hussein Onn Malaysia |
| language | English |
| last_indexed | 2024-03-05T21:57:12Z |
| publishDate | 2022 |
| publisher | Penerbit Universiti Teknologi Malaysia Press |
| record_format | dspace |
| spelling | uthm.eprints-75962022-08-29T07:35:54Z http://eprints.uthm.edu.my/7596/ Photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin: a preliminary investigation Hui, Ling Chua Huong, Audrey T Technology (General) Tissue oxygen monitoring systems, such as pulse oximeter, is unreliable in patients with compromised microcirculation. Modern imaging modalities such as Magnetic Resonance Imaging (MRI) offer good diagnostic accuracy at the expense of increased cost and complexity in their operations. This paper studies the use of photoacoustic (PA) phase change as a predictor of skin tissue oxygen levels. We used EPOCH 650 ultrasonic flaw detector with a longitudinal transducer for measurement of PA waves. This pilot study was conducted on six human subjects. The produced ultrasonic waves were collected from their anterior left arm under three experimental conditions, namely at rest, venous and arterial blood flow occlusions, for determination of hemoglobin absorption dependent phase change in tissue. The overall mean and standard deviation (STDEV) of phase angles for at rest condition are calculated as 1.43 ± 0.06 radians (rads). Higher phase angles are determined for diastolic and systolic occlusion pressures given by 1.69 ± 0.05 rads and 2.09 ± 0.06 rads, respectively. This work concluded that the feasibility of our PA system to monitor changes in tissue oxygen performance renders it a promising alternative for portable assessment and measurement of oxygen concentration within microcirculation environment. Penerbit Universiti Teknologi Malaysia Press 2022 Article PeerReviewed text en http://eprints.uthm.edu.my/7596/1/J14479_d64bd9f49a6c20d2038b05bf7136b1ff.pdf Hui, Ling Chua and Huong, Audrey (2022) Photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin: a preliminary investigation. Jurnal Teknologi (Sciences & Engineering), 84 (4). pp. 159-166. ISSN 2180–3722 https://doi.org/10.11113/jurnalteknologi.v84.18005 |
| spellingShingle | T Technology (General) Hui, Ling Chua Huong, Audrey Photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin: a preliminary investigation |
| title | Photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin: a preliminary investigation |
| title_full | Photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin: a preliminary investigation |
| title_fullStr | Photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin: a preliminary investigation |
| title_full_unstemmed | Photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin: a preliminary investigation |
| title_short | Photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin: a preliminary investigation |
| title_sort | photoacoustic phase angle for noninvasive monitoring of microcirculatory change in human skin a preliminary investigation |
| topic | T Technology (General) |
| url | http://eprints.uthm.edu.my/7596/1/J14479_d64bd9f49a6c20d2038b05bf7136b1ff.pdf |
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