Chemical constituent from the twigs of Malaysian Syrygium griffithii
Genus Syzygium (Myrtaceae), known as kelat, is the largest genus in Malaysia. Plants of this genus are scattered throughout all parts of Malaysia from high tide level to the summit of Gunung Tahan. Kelat or Kayu kelat is the name for most wild species that have small or inedible fruits and it refers...
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Springer Nature
2022
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| author | Abdullah, Siti Awanis Jamil, Shajarahtunnur Zainuddin, Zairunnisa |
| author_facet | Abdullah, Siti Awanis Jamil, Shajarahtunnur Zainuddin, Zairunnisa |
| author_sort | Abdullah, Siti Awanis |
| collection | ePrints |
| description | Genus Syzygium (Myrtaceae), known as kelat, is the largest genus in Malaysia. Plants of this genus are scattered throughout all parts of Malaysia from high tide level to the summit of Gunung Tahan. Kelat or Kayu kelat is the name for most wild species that have small or inedible fruits and it refers to the peculiarly rigid bark. Some Syzygium species were traditionally used for the treatment of numerous ailments such as fever, diarrhoea, dysentery, catarrh, diabetes, and asthma [1]. Previous study on Syzygium griffithii (Duthie) Merr. & L. M. Perry showed the presence of alkaloids, flavonoids, phenols, steroids, terpenes, and tannins in the leaves, twigs, and heartwood extracts [2]. As part of our continuing search to explore novel natural compounds from S. griffithii, a phytochemical study of the twig extract of S. griffithii was carried out. As a result, one flavonoid and five terpenes were successfully isolated and identified as pinocembrin (1), friedelin (2), lupeol (3), ß-sitosterol (4), ß-amyrin (5), and lupeol-3-acetate (6). Their structures were elucidated by extensive spectroscopic data analysis and comparison with respective literature data. The methanol extracts were also tested for their antioxidant (DPPH, ABTS, and FRAP) and a-glucosidase inhibitory activity. To the best of our knowledge, there are no reports on chemical constituents and bioactivity studies on twigs of S. griffithii. |
| first_indexed | 2024-03-05T21:30:45Z |
| format | Article |
| id | utm.eprints-104498 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T21:30:45Z |
| publishDate | 2022 |
| publisher | Springer Nature |
| record_format | dspace |
| spelling | utm.eprints-1044982024-02-21T07:26:48Z http://eprints.utm.my/104498/ Chemical constituent from the twigs of Malaysian Syrygium griffithii Abdullah, Siti Awanis Jamil, Shajarahtunnur Zainuddin, Zairunnisa QD Chemistry Genus Syzygium (Myrtaceae), known as kelat, is the largest genus in Malaysia. Plants of this genus are scattered throughout all parts of Malaysia from high tide level to the summit of Gunung Tahan. Kelat or Kayu kelat is the name for most wild species that have small or inedible fruits and it refers to the peculiarly rigid bark. Some Syzygium species were traditionally used for the treatment of numerous ailments such as fever, diarrhoea, dysentery, catarrh, diabetes, and asthma [1]. Previous study on Syzygium griffithii (Duthie) Merr. & L. M. Perry showed the presence of alkaloids, flavonoids, phenols, steroids, terpenes, and tannins in the leaves, twigs, and heartwood extracts [2]. As part of our continuing search to explore novel natural compounds from S. griffithii, a phytochemical study of the twig extract of S. griffithii was carried out. As a result, one flavonoid and five terpenes were successfully isolated and identified as pinocembrin (1), friedelin (2), lupeol (3), ß-sitosterol (4), ß-amyrin (5), and lupeol-3-acetate (6). Their structures were elucidated by extensive spectroscopic data analysis and comparison with respective literature data. The methanol extracts were also tested for their antioxidant (DPPH, ABTS, and FRAP) and a-glucosidase inhibitory activity. To the best of our knowledge, there are no reports on chemical constituents and bioactivity studies on twigs of S. griffithii. Springer Nature 2022 Article PeerReviewed Abdullah, Siti Awanis and Jamil, Shajarahtunnur and Zainuddin, Zairunnisa (2022) Chemical constituent from the twigs of Malaysian Syrygium griffithii. Chemistry of Natural Compounds, 58 (3). pp. 548-549. ISSN 0009-3130 http://dx.doi.org/10.1007/s10600-022-03731-9 DOI : 10.1007/s10600-022-03731-9 |
| spellingShingle | QD Chemistry Abdullah, Siti Awanis Jamil, Shajarahtunnur Zainuddin, Zairunnisa Chemical constituent from the twigs of Malaysian Syrygium griffithii |
| title | Chemical constituent from the twigs of Malaysian Syrygium griffithii |
| title_full | Chemical constituent from the twigs of Malaysian Syrygium griffithii |
| title_fullStr | Chemical constituent from the twigs of Malaysian Syrygium griffithii |
| title_full_unstemmed | Chemical constituent from the twigs of Malaysian Syrygium griffithii |
| title_short | Chemical constituent from the twigs of Malaysian Syrygium griffithii |
| title_sort | chemical constituent from the twigs of malaysian syrygium griffithii |
| topic | QD Chemistry |
| work_keys_str_mv | AT abdullahsitiawanis chemicalconstituentfromthetwigsofmalaysiansyrygiumgriffithii AT jamilshajarahtunnur chemicalconstituentfromthetwigsofmalaysiansyrygiumgriffithii AT zainuddinzairunnisa chemicalconstituentfromthetwigsofmalaysiansyrygiumgriffithii |