Mathematical modelling to predict the effect of vaccination on delay and rise of COVID-19 cases management

In this paper, a mathematical model based on COVID-19 is developed to study and manage disease outbreaks. The effect of vaccination with regard to its efficacy and percentage of population vaccinated in a closed population is investigated. To study virus transmission, the system employs six nonlinea...

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Main Authors: Charu Arora, Charu Arora, Poras Khetarpal, Poras Khetarpal, Saket Gupta, Saket Gupta, Nuzhat Fatema, Nuzhat Fatema, Malik, Hasmat, Afthanorhan, Asyraf
Format: Article
Language:English
Published: MDPI 2023
Subjects:
Online Access:http://eprints.utm.my/105670/1/HasmatMalik2023_MathematicalModellingtoPredicttheEffect.pdf
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author Charu Arora, Charu Arora
Poras Khetarpal, Poras Khetarpal
Saket Gupta, Saket Gupta
Nuzhat Fatema, Nuzhat Fatema
Malik, Hasmat
Afthanorhan, Asyraf
author_facet Charu Arora, Charu Arora
Poras Khetarpal, Poras Khetarpal
Saket Gupta, Saket Gupta
Nuzhat Fatema, Nuzhat Fatema
Malik, Hasmat
Afthanorhan, Asyraf
author_sort Charu Arora, Charu Arora
collection ePrints
description In this paper, a mathematical model based on COVID-19 is developed to study and manage disease outbreaks. The effect of vaccination with regard to its efficacy and percentage of population vaccinated in a closed population is investigated. To study virus transmission, the system employs six nonlinear ordinary differential equations with susceptible–exposed–asymptomatic–infected–vaccinated–recovered populations and the basic reproduction number are calculated. The proposed model describes for highly infectious diseases (such as COVID-19) in a closed containment area with no migration. This paper considers that the percentage of vaccinated population has a significant impact on the number of COVID-19 positive cases during the pandemic wave and examines how the pandemic rise time is delayed. Numerical simulation to investigate disease outbreaks when the community is undergoing vaccination is performed, taking the efficacy rate of the vaccine into account. Sensitivity Index values are calculated for the reproduction number and their relations with few other parameters are depicted.
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spelling utm.eprints-1056702024-05-13T07:00:29Z http://eprints.utm.my/105670/ Mathematical modelling to predict the effect of vaccination on delay and rise of COVID-19 cases management Charu Arora, Charu Arora Poras Khetarpal, Poras Khetarpal Saket Gupta, Saket Gupta Nuzhat Fatema, Nuzhat Fatema Malik, Hasmat Afthanorhan, Asyraf Q Science (General) T Technology (General) TK Electrical engineering. Electronics Nuclear engineering In this paper, a mathematical model based on COVID-19 is developed to study and manage disease outbreaks. The effect of vaccination with regard to its efficacy and percentage of population vaccinated in a closed population is investigated. To study virus transmission, the system employs six nonlinear ordinary differential equations with susceptible–exposed–asymptomatic–infected–vaccinated–recovered populations and the basic reproduction number are calculated. The proposed model describes for highly infectious diseases (such as COVID-19) in a closed containment area with no migration. This paper considers that the percentage of vaccinated population has a significant impact on the number of COVID-19 positive cases during the pandemic wave and examines how the pandemic rise time is delayed. Numerical simulation to investigate disease outbreaks when the community is undergoing vaccination is performed, taking the efficacy rate of the vaccine into account. Sensitivity Index values are calculated for the reproduction number and their relations with few other parameters are depicted. MDPI 2023-02 Article PeerReviewed application/pdf en http://eprints.utm.my/105670/1/HasmatMalik2023_MathematicalModellingtoPredicttheEffect.pdf Charu Arora, Charu Arora and Poras Khetarpal, Poras Khetarpal and Saket Gupta, Saket Gupta and Nuzhat Fatema, Nuzhat Fatema and Malik, Hasmat and Afthanorhan, Asyraf (2023) Mathematical modelling to predict the effect of vaccination on delay and rise of COVID-19 cases management. Mathematics, 11 (4). pp. 1-15. ISSN 2227-7390 http://dx.doi.org/10.3390/math11040821 DOI:10.3390/math11040821
spellingShingle Q Science (General)
T Technology (General)
TK Electrical engineering. Electronics Nuclear engineering
Charu Arora, Charu Arora
Poras Khetarpal, Poras Khetarpal
Saket Gupta, Saket Gupta
Nuzhat Fatema, Nuzhat Fatema
Malik, Hasmat
Afthanorhan, Asyraf
Mathematical modelling to predict the effect of vaccination on delay and rise of COVID-19 cases management
title Mathematical modelling to predict the effect of vaccination on delay and rise of COVID-19 cases management
title_full Mathematical modelling to predict the effect of vaccination on delay and rise of COVID-19 cases management
title_fullStr Mathematical modelling to predict the effect of vaccination on delay and rise of COVID-19 cases management
title_full_unstemmed Mathematical modelling to predict the effect of vaccination on delay and rise of COVID-19 cases management
title_short Mathematical modelling to predict the effect of vaccination on delay and rise of COVID-19 cases management
title_sort mathematical modelling to predict the effect of vaccination on delay and rise of covid 19 cases management
topic Q Science (General)
T Technology (General)
TK Electrical engineering. Electronics Nuclear engineering
url http://eprints.utm.my/105670/1/HasmatMalik2023_MathematicalModellingtoPredicttheEffect.pdf
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