Cardiovascular, respiratory and all-cause (natural) health endpoint estimation using a spatial approach in Malaysia

In 2016, the World Health Organization (WHO) estimated that approximately 4.2 million premature deaths worldwide were attributable to exposure to particulate matter 2.5 μm (PM2.5). This study assessed the environmental burden of disease attributable to PM2.5 at the national level in Malaysia. We est...

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Main Authors: Mazeli, Mohamad Iqbal, Pahrol, Muhammad Alfatih, Abdul Shakor, Ameerah Su'ad, Kanniah, Kasturi Devi, Omar, Mohd. Azahadi
Format: Article
Language:English
Published: Elsevier B.V. 2023
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Online Access:http://eprints.utm.my/106784/1/KasturiDeviKanniah2023_CardiovascularRespiratoryandAllCauseNatural.pdf
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author Mazeli, Mohamad Iqbal
Pahrol, Muhammad Alfatih
Abdul Shakor, Ameerah Su'ad
Kanniah, Kasturi Devi
Omar, Mohd. Azahadi
author_facet Mazeli, Mohamad Iqbal
Pahrol, Muhammad Alfatih
Abdul Shakor, Ameerah Su'ad
Kanniah, Kasturi Devi
Omar, Mohd. Azahadi
author_sort Mazeli, Mohamad Iqbal
collection ePrints
description In 2016, the World Health Organization (WHO) estimated that approximately 4.2 million premature deaths worldwide were attributable to exposure to particulate matter 2.5 μm (PM2.5). This study assessed the environmental burden of disease attributable to PM2.5 at the national level in Malaysia. We estimated the population-weighted exposure level (PWEL) of PM10 concentrations in Malaysia for 2000, 2008, and 2013 using aerosol optical density (AOD) data from publicly available remote sensing satellite data (MODIS Terra). The PWEL was then converted to PM2.5 using Malaysia's WHO ambient air conversion factor. We used AirQ+ 2.0 software to calculate all-cause (natural), ischemic heart disease (IHD), stroke, chronic obstructive pulmonary disease (COPD), lung cancer (LC), and acute lower respiratory infection (ALRI) excess deaths from the National Burden of Disease data for 2000, 2008 and 2013. The average PWELs for annual PM2.5 for 2000, 2008, and 2013 were 22 μg m-3, 18 μg m-3 and 24 μg m-3, respectively. Using the WHO 2005 Air Quality Guideline cut-off point of PM2.5 of 10 μg m-3, the estimated excess deaths for 2000, 2008, and 2013 from all-cause (natural) mortality were between 5893 and 9781 (95 % CI: 3347–12,791), COPD was between 164 and 957 (95 % CI: 95–1411), lung cancer was between 109 and 307 (95 % CI: 63–437), IHD was between 3 and 163 deaths, according to age groups (95 % CI: 2–394) and stroke was between 6 and 155 deaths, according to age groups (95 % CI: 3–261). An increase in estimated health endpoints was associated with increased estimated PWEL PM2.5 for 2013 compared to 2000 and 2008. Adhering the ambient PM2.5 level to the Malaysian Air Quality Standard IT-2 would reduce the national health endpoints mortality.
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spelling utm.eprints-1067842024-07-30T07:56:56Z http://eprints.utm.my/106784/ Cardiovascular, respiratory and all-cause (natural) health endpoint estimation using a spatial approach in Malaysia Mazeli, Mohamad Iqbal Pahrol, Muhammad Alfatih Abdul Shakor, Ameerah Su'ad Kanniah, Kasturi Devi Omar, Mohd. Azahadi Q Science (General) TD Environmental technology. Sanitary engineering In 2016, the World Health Organization (WHO) estimated that approximately 4.2 million premature deaths worldwide were attributable to exposure to particulate matter 2.5 μm (PM2.5). This study assessed the environmental burden of disease attributable to PM2.5 at the national level in Malaysia. We estimated the population-weighted exposure level (PWEL) of PM10 concentrations in Malaysia for 2000, 2008, and 2013 using aerosol optical density (AOD) data from publicly available remote sensing satellite data (MODIS Terra). The PWEL was then converted to PM2.5 using Malaysia's WHO ambient air conversion factor. We used AirQ+ 2.0 software to calculate all-cause (natural), ischemic heart disease (IHD), stroke, chronic obstructive pulmonary disease (COPD), lung cancer (LC), and acute lower respiratory infection (ALRI) excess deaths from the National Burden of Disease data for 2000, 2008 and 2013. The average PWELs for annual PM2.5 for 2000, 2008, and 2013 were 22 μg m-3, 18 μg m-3 and 24 μg m-3, respectively. Using the WHO 2005 Air Quality Guideline cut-off point of PM2.5 of 10 μg m-3, the estimated excess deaths for 2000, 2008, and 2013 from all-cause (natural) mortality were between 5893 and 9781 (95 % CI: 3347–12,791), COPD was between 164 and 957 (95 % CI: 95–1411), lung cancer was between 109 and 307 (95 % CI: 63–437), IHD was between 3 and 163 deaths, according to age groups (95 % CI: 2–394) and stroke was between 6 and 155 deaths, according to age groups (95 % CI: 3–261). An increase in estimated health endpoints was associated with increased estimated PWEL PM2.5 for 2013 compared to 2000 and 2008. Adhering the ambient PM2.5 level to the Malaysian Air Quality Standard IT-2 would reduce the national health endpoints mortality. Elsevier B.V. 2023 Article PeerReviewed application/pdf en http://eprints.utm.my/106784/1/KasturiDeviKanniah2023_CardiovascularRespiratoryandAllCauseNatural.pdf Mazeli, Mohamad Iqbal and Pahrol, Muhammad Alfatih and Abdul Shakor, Ameerah Su'ad and Kanniah, Kasturi Devi and Omar, Mohd. Azahadi (2023) Cardiovascular, respiratory and all-cause (natural) health endpoint estimation using a spatial approach in Malaysia. Science of the Total Environment, 874 (NA). pp. 1-9. ISSN 0048-9697 http://dx.doi.org/10.1016/j.scitotenv.2023.162130 DOI:10.1016/j.scitotenv.2023.162130
spellingShingle Q Science (General)
TD Environmental technology. Sanitary engineering
Mazeli, Mohamad Iqbal
Pahrol, Muhammad Alfatih
Abdul Shakor, Ameerah Su'ad
Kanniah, Kasturi Devi
Omar, Mohd. Azahadi
Cardiovascular, respiratory and all-cause (natural) health endpoint estimation using a spatial approach in Malaysia
title Cardiovascular, respiratory and all-cause (natural) health endpoint estimation using a spatial approach in Malaysia
title_full Cardiovascular, respiratory and all-cause (natural) health endpoint estimation using a spatial approach in Malaysia
title_fullStr Cardiovascular, respiratory and all-cause (natural) health endpoint estimation using a spatial approach in Malaysia
title_full_unstemmed Cardiovascular, respiratory and all-cause (natural) health endpoint estimation using a spatial approach in Malaysia
title_short Cardiovascular, respiratory and all-cause (natural) health endpoint estimation using a spatial approach in Malaysia
title_sort cardiovascular respiratory and all cause natural health endpoint estimation using a spatial approach in malaysia
topic Q Science (General)
TD Environmental technology. Sanitary engineering
url http://eprints.utm.my/106784/1/KasturiDeviKanniah2023_CardiovascularRespiratoryandAllCauseNatural.pdf
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