Visible-light-driven photocatalytic dual-layer hollow fibre membrane ameliorates the changes of bisphenol A exposure in gastrointestinal tract
Various treatments of choice are available to overcome contamination of bisphenol A (BPA) in the environment including membrane technologies, however, the treatment still releases contaminants that threaten the human being. Therefore, the present study is conducted to investigate the degradation of...
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| Format: | Article |
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Springer Science and Business Media Deutschland GmbH
2023
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| author | Kamaludin, Roziana Othman, Mohd. Hafiz Dzarfan Sheikh Abdul Kadir, Siti Hamimah Khan, Jesmine Ismail, Ahmad Fauzi A. Rahman, Mukhlis Jaafar, Juhana |
| author_facet | Kamaludin, Roziana Othman, Mohd. Hafiz Dzarfan Sheikh Abdul Kadir, Siti Hamimah Khan, Jesmine Ismail, Ahmad Fauzi A. Rahman, Mukhlis Jaafar, Juhana |
| author_sort | Kamaludin, Roziana |
| collection | ePrints |
| description | Various treatments of choice are available to overcome contamination of bisphenol A (BPA) in the environment including membrane technologies, however, the treatment still releases contaminants that threaten the human being. Therefore, the present study is conducted to investigate the degradation of BPA by recently developed visible-light-driven photocatalytic nitrogen-doping titanium dioxide (N-doped TiO2) dual-layer hollow fibre (DLHF) membrane and its efficiency in reducing the level of BPA in contaminated water. Fabricated with suitable polymer/photocatalyst (15/7.5 wt.%) via co-extrusion spinning method, the DLHF was characterized morphologically, evaluated for BPA degradation by using submerged photocatalytic membrane reactor under visible light irradiations followed by the investigation of intermediates formed. BPA exposure effects were accessed by immunohistochemistry staining of gastrointestinal sample obtained from animal model. BPA has been successfully degraded up to 72.5% with 2 intermediate products, B1 and B2, being identified followed by total degradation of BPA. BPA exposure leads to the high-intensity IHC staining of Claudin family which indicated the disruption of small intestinal barrier (SIB) integrity. Low IHC staining intensity of Claudin family in treated BPA group demonstrated that reducing the level of BPA by N-doped TiO2 DLHF is capable of protecting the important component of SIB. Altogether, the fabricated photocatalytic DLHF membrane is expected to have an outstanding potential in removing BPA and its health effect for household water treatment to fulfil the public focus on the safety of their household water and their need to consume clean water. |
| first_indexed | 2024-09-24T00:03:55Z |
| format | Article |
| id | utm.eprints-106857 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-09-24T00:03:55Z |
| publishDate | 2023 |
| publisher | Springer Science and Business Media Deutschland GmbH |
| record_format | dspace |
| spelling | utm.eprints-1068572024-08-01T05:38:05Z http://eprints.utm.my/106857/ Visible-light-driven photocatalytic dual-layer hollow fibre membrane ameliorates the changes of bisphenol A exposure in gastrointestinal tract Kamaludin, Roziana Othman, Mohd. Hafiz Dzarfan Sheikh Abdul Kadir, Siti Hamimah Khan, Jesmine Ismail, Ahmad Fauzi A. Rahman, Mukhlis Jaafar, Juhana TP Chemical technology Various treatments of choice are available to overcome contamination of bisphenol A (BPA) in the environment including membrane technologies, however, the treatment still releases contaminants that threaten the human being. Therefore, the present study is conducted to investigate the degradation of BPA by recently developed visible-light-driven photocatalytic nitrogen-doping titanium dioxide (N-doped TiO2) dual-layer hollow fibre (DLHF) membrane and its efficiency in reducing the level of BPA in contaminated water. Fabricated with suitable polymer/photocatalyst (15/7.5 wt.%) via co-extrusion spinning method, the DLHF was characterized morphologically, evaluated for BPA degradation by using submerged photocatalytic membrane reactor under visible light irradiations followed by the investigation of intermediates formed. BPA exposure effects were accessed by immunohistochemistry staining of gastrointestinal sample obtained from animal model. BPA has been successfully degraded up to 72.5% with 2 intermediate products, B1 and B2, being identified followed by total degradation of BPA. BPA exposure leads to the high-intensity IHC staining of Claudin family which indicated the disruption of small intestinal barrier (SIB) integrity. Low IHC staining intensity of Claudin family in treated BPA group demonstrated that reducing the level of BPA by N-doped TiO2 DLHF is capable of protecting the important component of SIB. Altogether, the fabricated photocatalytic DLHF membrane is expected to have an outstanding potential in removing BPA and its health effect for household water treatment to fulfil the public focus on the safety of their household water and their need to consume clean water. Springer Science and Business Media Deutschland GmbH 2023 Article PeerReviewed Kamaludin, Roziana and Othman, Mohd. Hafiz Dzarfan and Sheikh Abdul Kadir, Siti Hamimah and Khan, Jesmine and Ismail, Ahmad Fauzi and A. Rahman, Mukhlis and Jaafar, Juhana (2023) Visible-light-driven photocatalytic dual-layer hollow fibre membrane ameliorates the changes of bisphenol A exposure in gastrointestinal tract. Environmental Science and Pollution Research, 30 (1). pp. 259-273. ISSN 0944-1344 http://dx.doi.org/10.1007/s11356-022-22121-w DOI : 10.1007/s11356-022-22121-w |
| spellingShingle | TP Chemical technology Kamaludin, Roziana Othman, Mohd. Hafiz Dzarfan Sheikh Abdul Kadir, Siti Hamimah Khan, Jesmine Ismail, Ahmad Fauzi A. Rahman, Mukhlis Jaafar, Juhana Visible-light-driven photocatalytic dual-layer hollow fibre membrane ameliorates the changes of bisphenol A exposure in gastrointestinal tract |
| title | Visible-light-driven photocatalytic dual-layer hollow fibre membrane ameliorates the changes of bisphenol A exposure in gastrointestinal tract |
| title_full | Visible-light-driven photocatalytic dual-layer hollow fibre membrane ameliorates the changes of bisphenol A exposure in gastrointestinal tract |
| title_fullStr | Visible-light-driven photocatalytic dual-layer hollow fibre membrane ameliorates the changes of bisphenol A exposure in gastrointestinal tract |
| title_full_unstemmed | Visible-light-driven photocatalytic dual-layer hollow fibre membrane ameliorates the changes of bisphenol A exposure in gastrointestinal tract |
| title_short | Visible-light-driven photocatalytic dual-layer hollow fibre membrane ameliorates the changes of bisphenol A exposure in gastrointestinal tract |
| title_sort | visible light driven photocatalytic dual layer hollow fibre membrane ameliorates the changes of bisphenol a exposure in gastrointestinal tract |
| topic | TP Chemical technology |
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