Impact of saffron as an anti-cancer and anti-tumor herb

Cancer continues to represent the largest cause of mortality in the world and claims over 6 million lives each year. An extremely promising strategy for cancer prevention today is chemoprevention, which is defined as the use of synthetic or natural agents (alone or in combination) to block the devel...

Full description

Bibliographic Details
Main Authors: Abd. Majid, Fadzilah Adibah, Sarmidi, Mohamad Roji, Chermahini, S. H., Taghizadeh, E., Salehnezhad, S.
Format: Article
Published: Academic Journals 2010
Subjects:
_version_ 1796856155979382784
author Abd. Majid, Fadzilah Adibah
Sarmidi, Mohamad Roji
Chermahini, S. H.
Taghizadeh, E.
Salehnezhad, S.
author_facet Abd. Majid, Fadzilah Adibah
Sarmidi, Mohamad Roji
Chermahini, S. H.
Taghizadeh, E.
Salehnezhad, S.
author_sort Abd. Majid, Fadzilah Adibah
collection ePrints
description Cancer continues to represent the largest cause of mortality in the world and claims over 6 million lives each year. An extremely promising strategy for cancer prevention today is chemoprevention, which is defined as the use of synthetic or natural agents (alone or in combination) to block the development of cancer in human beings. Plants, vegetables, herbs and spices used in folk and traditional medicine have been accepted currently as one of the main sources of cancer chemopreventive drug discovery and development. This review gives an overview from one of this herbs and spices that is saffron. The chemical composition of saffron has attracted the interest of several research groups during the last decades, and among the estimated more than 150 volatile and several nonvolatile compounds of saffron, approximately 40 – 50 constituents have already been identified. Oral administration of saffron extract inhibited the growth of mouse tumors that were derived from three different kinds of cancer cells and significantly increased the life spans of treated tumor-bearing mice.
first_indexed 2024-03-05T18:39:16Z
format Article
id utm.eprints-26175
institution Universiti Teknologi Malaysia - ePrints
last_indexed 2024-03-05T18:39:16Z
publishDate 2010
publisher Academic Journals
record_format dspace
spelling utm.eprints-261752018-11-30T06:23:05Z http://eprints.utm.my/26175/ Impact of saffron as an anti-cancer and anti-tumor herb Abd. Majid, Fadzilah Adibah Sarmidi, Mohamad Roji Chermahini, S. H. Taghizadeh, E. Salehnezhad, S. QD Chemistry Cancer continues to represent the largest cause of mortality in the world and claims over 6 million lives each year. An extremely promising strategy for cancer prevention today is chemoprevention, which is defined as the use of synthetic or natural agents (alone or in combination) to block the development of cancer in human beings. Plants, vegetables, herbs and spices used in folk and traditional medicine have been accepted currently as one of the main sources of cancer chemopreventive drug discovery and development. This review gives an overview from one of this herbs and spices that is saffron. The chemical composition of saffron has attracted the interest of several research groups during the last decades, and among the estimated more than 150 volatile and several nonvolatile compounds of saffron, approximately 40 – 50 constituents have already been identified. Oral administration of saffron extract inhibited the growth of mouse tumors that were derived from three different kinds of cancer cells and significantly increased the life spans of treated tumor-bearing mice. Academic Journals 2010-11 Article PeerReviewed Abd. Majid, Fadzilah Adibah and Sarmidi, Mohamad Roji and Chermahini, S. H. and Taghizadeh, E. and Salehnezhad, S. (2010) Impact of saffron as an anti-cancer and anti-tumor herb. African Journal Of Pharmacy And Pharmacology, 4 (11). 834 - 840. ISSN 1996-0816 https://academicjournals.org/journal/AJPP/article-abstract/58B3CC336792
spellingShingle QD Chemistry
Abd. Majid, Fadzilah Adibah
Sarmidi, Mohamad Roji
Chermahini, S. H.
Taghizadeh, E.
Salehnezhad, S.
Impact of saffron as an anti-cancer and anti-tumor herb
title Impact of saffron as an anti-cancer and anti-tumor herb
title_full Impact of saffron as an anti-cancer and anti-tumor herb
title_fullStr Impact of saffron as an anti-cancer and anti-tumor herb
title_full_unstemmed Impact of saffron as an anti-cancer and anti-tumor herb
title_short Impact of saffron as an anti-cancer and anti-tumor herb
title_sort impact of saffron as an anti cancer and anti tumor herb
topic QD Chemistry
work_keys_str_mv AT abdmajidfadzilahadibah impactofsaffronasananticancerandantitumorherb
AT sarmidimohamadroji impactofsaffronasananticancerandantitumorherb
AT chermahinish impactofsaffronasananticancerandantitumorherb
AT taghizadehe impactofsaffronasananticancerandantitumorherb
AT salehnezhads impactofsaffronasananticancerandantitumorherb