Nanoindentation methods to measure viscoelastic properties of single cells using sharp, flat, and buckling tips inside ESEM
In this paper, methods to measure viscoelastic properties of time-dependent materials are proposed using sharp, flat, and buckling tips inside an environmental SEM. Single W303 yeast cells were employed in this study. Each of the tips was used to indent single cells in a nanoindentation test. Three...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Published: |
IEEE Computational Intelligence Society
2010
|
| Subjects: |
| _version_ | 1796856171749965824 |
|---|---|
| author | Ahmad, Mohd. Ridzuan Nakajima, M. Kojima, S. Homma, M. Fukuda, T. |
| author_facet | Ahmad, Mohd. Ridzuan Nakajima, M. Kojima, S. Homma, M. Fukuda, T. |
| author_sort | Ahmad, Mohd. Ridzuan |
| collection | ePrints |
| description | In this paper, methods to measure viscoelastic properties of time-dependent materials are proposed using sharp, flat, and buckling tips inside an environmental SEM. Single W303 yeast cells were employed in this study. Each of the tips was used to indent single cells in a nanoindentation test. Three loading histories were used: 1) a ramp loading history, in which a sharp indenter was used; 2) a step loading history, in which a flat indenter was implemented; and 3) a fast unloading history, in which a buckling nanoneedle was applied. Analysis of the viscoelastic properties of single cells was performed for each of the loading histories by choosing an appropriate theory between the correspondence principle and the functional equation. Results from each of the tests show good agreement, from which strong conclusion can be drawn. |
| first_indexed | 2024-03-05T18:39:30Z |
| format | Article |
| id | utm.eprints-26260 |
| institution | Universiti Teknologi Malaysia - ePrints |
| last_indexed | 2024-03-05T18:39:30Z |
| publishDate | 2010 |
| publisher | IEEE Computational Intelligence Society |
| record_format | dspace |
| spelling | utm.eprints-262602017-10-17T03:14:30Z http://eprints.utm.my/26260/ Nanoindentation methods to measure viscoelastic properties of single cells using sharp, flat, and buckling tips inside ESEM Ahmad, Mohd. Ridzuan Nakajima, M. Kojima, S. Homma, M. Fukuda, T. TK Electrical engineering. Electronics Nuclear engineering In this paper, methods to measure viscoelastic properties of time-dependent materials are proposed using sharp, flat, and buckling tips inside an environmental SEM. Single W303 yeast cells were employed in this study. Each of the tips was used to indent single cells in a nanoindentation test. Three loading histories were used: 1) a ramp loading history, in which a sharp indenter was used; 2) a step loading history, in which a flat indenter was implemented; and 3) a fast unloading history, in which a buckling nanoneedle was applied. Analysis of the viscoelastic properties of single cells was performed for each of the loading histories by choosing an appropriate theory between the correspondence principle and the functional equation. Results from each of the tests show good agreement, from which strong conclusion can be drawn. IEEE Computational Intelligence Society 2010 Article PeerReviewed Ahmad, Mohd. Ridzuan and Nakajima, M. and Kojima, S. and Homma, M. and Fukuda, T. (2010) Nanoindentation methods to measure viscoelastic properties of single cells using sharp, flat, and buckling tips inside ESEM. IEEE Transactions on Nanobioscience, 9 (1). p. 40900. ISSN 1536-1241 http://dx.doi.org/10.1109/TNB.2009.2034849 DOI:10.1109/TNB.2009.2034849 |
| spellingShingle | TK Electrical engineering. Electronics Nuclear engineering Ahmad, Mohd. Ridzuan Nakajima, M. Kojima, S. Homma, M. Fukuda, T. Nanoindentation methods to measure viscoelastic properties of single cells using sharp, flat, and buckling tips inside ESEM |
| title | Nanoindentation methods to measure viscoelastic properties of single cells using sharp, flat, and buckling tips inside ESEM |
| title_full | Nanoindentation methods to measure viscoelastic properties of single cells using sharp, flat, and buckling tips inside ESEM |
| title_fullStr | Nanoindentation methods to measure viscoelastic properties of single cells using sharp, flat, and buckling tips inside ESEM |
| title_full_unstemmed | Nanoindentation methods to measure viscoelastic properties of single cells using sharp, flat, and buckling tips inside ESEM |
| title_short | Nanoindentation methods to measure viscoelastic properties of single cells using sharp, flat, and buckling tips inside ESEM |
| title_sort | nanoindentation methods to measure viscoelastic properties of single cells using sharp flat and buckling tips inside esem |
| topic | TK Electrical engineering. Electronics Nuclear engineering |
| work_keys_str_mv | AT ahmadmohdridzuan nanoindentationmethodstomeasureviscoelasticpropertiesofsinglecellsusingsharpflatandbucklingtipsinsideesem AT nakajimam nanoindentationmethodstomeasureviscoelasticpropertiesofsinglecellsusingsharpflatandbucklingtipsinsideesem AT kojimas nanoindentationmethodstomeasureviscoelasticpropertiesofsinglecellsusingsharpflatandbucklingtipsinsideesem AT hommam nanoindentationmethodstomeasureviscoelasticpropertiesofsinglecellsusingsharpflatandbucklingtipsinsideesem AT fukudat nanoindentationmethodstomeasureviscoelasticpropertiesofsinglecellsusingsharpflatandbucklingtipsinsideesem |