Modeling of bio scaffolds: structural and fluid transport characterization
Scaffolds play a key role in tissue engineering and can be produced in many different ways depending on the applications and the materials used. Most researchers used an experimental trialand- error approach into new biomaterials but computer simulation applied to tissue engineering can offer a more...
Main Authors: | , , , |
---|---|
Format: | Article |
Published: |
World Academy of Science Engineering and Technology
2011
|
Subjects: |
_version_ | 1796856554850353152 |
---|---|
author | Sadir, Sahba Abdul Kadir, Mohammed Rafiq Ochsner, Andreas Harun, Muhamad Noor |
author_facet | Sadir, Sahba Abdul Kadir, Mohammed Rafiq Ochsner, Andreas Harun, Muhamad Noor |
author_sort | Sadir, Sahba |
collection | ePrints |
description | Scaffolds play a key role in tissue engineering and can be produced in many different ways depending on the applications and the materials used. Most researchers used an experimental trialand- error approach into new biomaterials but computer simulation applied to tissue engineering can offer a more exhaustive approach to test and screen out biomaterials. This paper develops the model of scaffolds and Computational Fluid Dynamics that show the value of computer simulations in determining the influence of the geometrical scaffold parameter porosity, pore size and shape on the permeability of scaffolds, magnitude of velocity, drop pressure, shear stress distribution and level and the proper design of the geometry of the scaffold. This creates a need for more advanced studies that include aspects of dynamic conditions of a micro fluid passing through the scaffold were characterized for tissue engineering applications and differentiation of tissues within scaffolds. |
first_indexed | 2024-03-05T18:44:47Z |
format | Article |
id | utm.eprints-29435 |
institution | Universiti Teknologi Malaysia - ePrints |
last_indexed | 2024-03-05T18:44:47Z |
publishDate | 2011 |
publisher | World Academy of Science Engineering and Technology |
record_format | dspace |
spelling | utm.eprints-294352019-03-31T08:23:07Z http://eprints.utm.my/29435/ Modeling of bio scaffolds: structural and fluid transport characterization Sadir, Sahba Abdul Kadir, Mohammed Rafiq Ochsner, Andreas Harun, Muhamad Noor TJ Mechanical engineering and machinery Scaffolds play a key role in tissue engineering and can be produced in many different ways depending on the applications and the materials used. Most researchers used an experimental trialand- error approach into new biomaterials but computer simulation applied to tissue engineering can offer a more exhaustive approach to test and screen out biomaterials. This paper develops the model of scaffolds and Computational Fluid Dynamics that show the value of computer simulations in determining the influence of the geometrical scaffold parameter porosity, pore size and shape on the permeability of scaffolds, magnitude of velocity, drop pressure, shear stress distribution and level and the proper design of the geometry of the scaffold. This creates a need for more advanced studies that include aspects of dynamic conditions of a micro fluid passing through the scaffold were characterized for tissue engineering applications and differentiation of tissues within scaffolds. World Academy of Science Engineering and Technology 2011-07 Article PeerReviewed Sadir, Sahba and Abdul Kadir, Mohammed Rafiq and Ochsner, Andreas and Harun, Muhamad Noor (2011) Modeling of bio scaffolds: structural and fluid transport characterization. World Academy of Science, Engineering and Technology, 55 . pp. 1091-1096. ISSN 2010-376X https://waset.org/publications/11844/modeling-of-bio-scaffolds-structural-and-fluid-transport-characterization |
spellingShingle | TJ Mechanical engineering and machinery Sadir, Sahba Abdul Kadir, Mohammed Rafiq Ochsner, Andreas Harun, Muhamad Noor Modeling of bio scaffolds: structural and fluid transport characterization |
title | Modeling of bio scaffolds: structural and fluid transport characterization |
title_full | Modeling of bio scaffolds: structural and fluid transport characterization |
title_fullStr | Modeling of bio scaffolds: structural and fluid transport characterization |
title_full_unstemmed | Modeling of bio scaffolds: structural and fluid transport characterization |
title_short | Modeling of bio scaffolds: structural and fluid transport characterization |
title_sort | modeling of bio scaffolds structural and fluid transport characterization |
topic | TJ Mechanical engineering and machinery |
work_keys_str_mv | AT sadirsahba modelingofbioscaffoldsstructuralandfluidtransportcharacterization AT abdulkadirmohammedrafiq modelingofbioscaffoldsstructuralandfluidtransportcharacterization AT ochsnerandreas modelingofbioscaffoldsstructuralandfluidtransportcharacterization AT harunmuhamadnoor modelingofbioscaffoldsstructuralandfluidtransportcharacterization |