Synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications

A new hydrogel was synthesized based on polyacrylamide and sodium carboxymethylcellulose. N,N'-Methylenebisacrylamide (MBA) was used as crosslinker and ammonium persulfate (APS) and N,N,N',N'-tetra-methylethylenediamine (TEMED) were utilized as initiators. Moreover, The MgO nanopartic...

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Main Author: Asgharzadehahmadi, Seyed Ali
Format: Thesis
Language:English
Published: 2012
Subjects:
Online Access:http://eprints.utm.my/32550/1/SeyedAliAsgharzadehamadiMFKK2012.pdf
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author Asgharzadehahmadi, Seyed Ali
author_facet Asgharzadehahmadi, Seyed Ali
author_sort Asgharzadehahmadi, Seyed Ali
collection ePrints
description A new hydrogel was synthesized based on polyacrylamide and sodium carboxymethylcellulose. N,N'-Methylenebisacrylamide (MBA) was used as crosslinker and ammonium persulfate (APS) and N,N,N',N'-tetra-methylethylenediamine (TEMED) were utilized as initiators. Moreover, The MgO nanoparticles were added to the hydrogel network in order to investigate the antibacterial activity of synthesized polymer. Characterizations of hydrogels were carried out using Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD) and Field Emission Scanning Electron Microscope (FESEM). The physical and chemical characterizations of the prepared hydrogels give valuable information on the morphological structure of polymer, swelling behavior, bonding formation of gels and physical properties. It can be concluded that by incorporation of NaCMC the hydrogel properties are retained chemically and the physical properties are clearly being enhanced in the aspects of swelling capacity, strength and flexibility. This study also investigates the antibacterial activities of prepared hydrogels against Escherichia coli which is a Gram negative food pathogenic bacteria. For this purpose, agar diffusion test or agar plate test was carried out and inhibition area for each hydrogel was determined. The inhibition zone for acrylamide hydrogel with NaCMC was about 4.52 cm2 since this area for MgO nanocomposite containing 0.03 gram of MgO was 15.19 cm2.
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spelling utm.eprints-325502021-06-20T09:41:59Z http://eprints.utm.my/32550/ Synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications Asgharzadehahmadi, Seyed Ali TP Chemical technology A new hydrogel was synthesized based on polyacrylamide and sodium carboxymethylcellulose. N,N'-Methylenebisacrylamide (MBA) was used as crosslinker and ammonium persulfate (APS) and N,N,N',N'-tetra-methylethylenediamine (TEMED) were utilized as initiators. Moreover, The MgO nanoparticles were added to the hydrogel network in order to investigate the antibacterial activity of synthesized polymer. Characterizations of hydrogels were carried out using Fourier Transform Infrared Spectroscopy (FTIR), X-ray diffraction (XRD) and Field Emission Scanning Electron Microscope (FESEM). The physical and chemical characterizations of the prepared hydrogels give valuable information on the morphological structure of polymer, swelling behavior, bonding formation of gels and physical properties. It can be concluded that by incorporation of NaCMC the hydrogel properties are retained chemically and the physical properties are clearly being enhanced in the aspects of swelling capacity, strength and flexibility. This study also investigates the antibacterial activities of prepared hydrogels against Escherichia coli which is a Gram negative food pathogenic bacteria. For this purpose, agar diffusion test or agar plate test was carried out and inhibition area for each hydrogel was determined. The inhibition zone for acrylamide hydrogel with NaCMC was about 4.52 cm2 since this area for MgO nanocomposite containing 0.03 gram of MgO was 15.19 cm2. 2012-09 Thesis NonPeerReviewed application/pdf en http://eprints.utm.my/32550/1/SeyedAliAsgharzadehamadiMFKK2012.pdf Asgharzadehahmadi, Seyed Ali (2012) Synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications. Masters thesis, Universiti Teknologi Malaysia, Faculty of Chemical Engineering.
spellingShingle TP Chemical technology
Asgharzadehahmadi, Seyed Ali
Synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications
title Synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications
title_full Synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications
title_fullStr Synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications
title_full_unstemmed Synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications
title_short Synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications
title_sort synthesis and characterization of polyacrylamide based hydrogel containing magnesium oxide nanoparticles for antibacterial applications
topic TP Chemical technology
url http://eprints.utm.my/32550/1/SeyedAliAsgharzadehamadiMFKK2012.pdf
work_keys_str_mv AT asgharzadehahmadiseyedali synthesisandcharacterizationofpolyacrylamidebasedhydrogelcontainingmagnesiumoxidenanoparticlesforantibacterialapplications