Porous biodegradable metals for hard tissue scaffolds: a review
Scaffolds have been utilized in tissue regeneration to facilitate the formation and maturation of new tissues or organs where a balance between temporary mechanical support and mass transport (degradation and cell growth) is ideally achieved. Polymers have been widely chosen as tissue scaffolding ma...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Hindawi Publishing Corporation
2012
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| Online Access: | http://eprints.utm.my/33465/1/HHermawan2012_PorousBiodegradableMetalsforHardTissue.pdf |
| _version_ | 1796857189454839808 |
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| author | Yusop, A. H. Bakir, A. A. Shaharom, N. A. Abdul Kadir, Mohammed Rafiq Hermawan, Hendra |
| author_facet | Yusop, A. H. Bakir, A. A. Shaharom, N. A. Abdul Kadir, Mohammed Rafiq Hermawan, Hendra |
| author_sort | Yusop, A. H. |
| collection | ePrints |
| description | Scaffolds have been utilized in tissue regeneration to facilitate the formation and maturation of new tissues or organs where a balance between temporary mechanical support and mass transport (degradation and cell growth) is ideally achieved. Polymers have been widely chosen as tissue scaffolding material having a good combination of biodegradability, biocompatibility, and porous structure. Metals that can degrade in physiological environment, namely, biodegradable metals, are proposed as potential materials for hard tissue scaffolding where biodegradable polymers are often considered as having poor mechanical properties. Biodegradable metal scaffolds have showed interesting mechanical property that was close to that of human bone with tailored degradation behaviour. The current promising fabrication technique for making scaffolds, such as computation-aided solid free-form method, can be easily applied to metals. With further optimization in topologically ordered porosity design exploiting material property and fabrication technique, porous biodegradable metals could be the potential materials for making hard tissue scaffolds. |
| first_indexed | 2024-03-05T18:54:03Z |
| format | Article |
| id | utm.eprints-33465 |
| institution | Universiti Teknologi Malaysia - ePrints |
| language | English |
| last_indexed | 2024-03-05T18:54:03Z |
| publishDate | 2012 |
| publisher | Hindawi Publishing Corporation |
| record_format | dspace |
| spelling | utm.eprints-334652018-10-14T08:19:07Z http://eprints.utm.my/33465/ Porous biodegradable metals for hard tissue scaffolds: a review Yusop, A. H. Bakir, A. A. Shaharom, N. A. Abdul Kadir, Mohammed Rafiq Hermawan, Hendra R Medicine (General) Scaffolds have been utilized in tissue regeneration to facilitate the formation and maturation of new tissues or organs where a balance between temporary mechanical support and mass transport (degradation and cell growth) is ideally achieved. Polymers have been widely chosen as tissue scaffolding material having a good combination of biodegradability, biocompatibility, and porous structure. Metals that can degrade in physiological environment, namely, biodegradable metals, are proposed as potential materials for hard tissue scaffolding where biodegradable polymers are often considered as having poor mechanical properties. Biodegradable metal scaffolds have showed interesting mechanical property that was close to that of human bone with tailored degradation behaviour. The current promising fabrication technique for making scaffolds, such as computation-aided solid free-form method, can be easily applied to metals. With further optimization in topologically ordered porosity design exploiting material property and fabrication technique, porous biodegradable metals could be the potential materials for making hard tissue scaffolds. Hindawi Publishing Corporation 2012 Article PeerReviewed application/pdf en http://eprints.utm.my/33465/1/HHermawan2012_PorousBiodegradableMetalsforHardTissue.pdf Yusop, A. H. and Bakir, A. A. and Shaharom, N. A. and Abdul Kadir, Mohammed Rafiq and Hermawan, Hendra (2012) Porous biodegradable metals for hard tissue scaffolds: a review. International Journal of Biomaterials, 2012 . pp. 1-10. ISSN 1687-8787 https://www.hindawi.com/journals/ijbm/2012/641430/ DOI:10.1155/2012/641430 |
| spellingShingle | R Medicine (General) Yusop, A. H. Bakir, A. A. Shaharom, N. A. Abdul Kadir, Mohammed Rafiq Hermawan, Hendra Porous biodegradable metals for hard tissue scaffolds: a review |
| title | Porous biodegradable metals for hard tissue scaffolds: a review |
| title_full | Porous biodegradable metals for hard tissue scaffolds: a review |
| title_fullStr | Porous biodegradable metals for hard tissue scaffolds: a review |
| title_full_unstemmed | Porous biodegradable metals for hard tissue scaffolds: a review |
| title_short | Porous biodegradable metals for hard tissue scaffolds: a review |
| title_sort | porous biodegradable metals for hard tissue scaffolds a review |
| topic | R Medicine (General) |
| url | http://eprints.utm.my/33465/1/HHermawan2012_PorousBiodegradableMetalsforHardTissue.pdf |
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