Monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors
The intestinal tract is one of the main organs that, after hemorrhage or shock, appears to be involved in an ischemic/reperfusion injury. Metabolic substances, such as glucose and lactate are useful measurements for the monitoring of intestinal ischemia, since this provokes variation of intracellula...
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IEEE
2012
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author | Corcoles Perpinan, Emma Paola Boutelle, M. G. Deeba, S. Hanna, G. B. Darzi, A. |
author_facet | Corcoles Perpinan, Emma Paola Boutelle, M. G. Deeba, S. Hanna, G. B. Darzi, A. |
author_sort | Corcoles Perpinan, Emma Paola |
collection | ePrints |
description | The intestinal tract is one of the main organs that, after hemorrhage or shock, appears to be involved in an ischemic/reperfusion injury. Metabolic substances, such as glucose and lactate are useful measurements for the monitoring of intestinal ischemia, since this provokes variation of intracellular biochemical markers. In order to identify the ischemic/reperfusion mechanism adequately, physiological monitoring of the bowel under a different stress condition is required. Biomarkers were monitored during hypoxic conditions induced in a swine model to investigate the effect of this physiological variable on metabolic rates. Results showed that hypoxia could have different effects on bowel dialysate metabolites levels depending on tissue capabilities. |
first_indexed | 2024-03-05T18:57:46Z |
format | Book Section |
id | utm.eprints-35722 |
institution | Universiti Teknologi Malaysia - ePrints |
last_indexed | 2024-03-05T18:57:46Z |
publishDate | 2012 |
publisher | IEEE |
record_format | dspace |
spelling | utm.eprints-357222017-02-02T05:24:27Z http://eprints.utm.my/35722/ Monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors Corcoles Perpinan, Emma Paola Boutelle, M. G. Deeba, S. Hanna, G. B. Darzi, A. R Medicine (General) The intestinal tract is one of the main organs that, after hemorrhage or shock, appears to be involved in an ischemic/reperfusion injury. Metabolic substances, such as glucose and lactate are useful measurements for the monitoring of intestinal ischemia, since this provokes variation of intracellular biochemical markers. In order to identify the ischemic/reperfusion mechanism adequately, physiological monitoring of the bowel under a different stress condition is required. Biomarkers were monitored during hypoxic conditions induced in a swine model to investigate the effect of this physiological variable on metabolic rates. Results showed that hypoxia could have different effects on bowel dialysate metabolites levels depending on tissue capabilities. IEEE 2012 Book Section PeerReviewed Corcoles Perpinan, Emma Paola and Boutelle, M. G. and Deeba, S. and Hanna, G. B. and Darzi, A. (2012) Monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors. In: 2012 International Conference on Biomedical Engineering, ICoBE 2012. IEEE, New York, USA, pp. 60-62. ISBN 978-145771989-9 http://dx.doi.org/10.1109/ICoBE.2012.6178955 DOI:10.1109/ICoBE.2012.6178955 |
spellingShingle | R Medicine (General) Corcoles Perpinan, Emma Paola Boutelle, M. G. Deeba, S. Hanna, G. B. Darzi, A. Monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors |
title | Monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors |
title_full | Monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors |
title_fullStr | Monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors |
title_full_unstemmed | Monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors |
title_short | Monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors |
title_sort | monitoring the effect of hypoxia in bowel dialysate metabolites levels with online biosensors |
topic | R Medicine (General) |
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