Modeling of blood flow in stenosed artery with a clot

The presence of blood clot in the blood stream can lead to partial or even complete blockage of the blood vessel. The condition can get worse in a stenosed artery. The clot will alter the flow field and modify the pressure distribution. To understand the changes in the blood flow due to presence of...

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Main Author: Rubai, Jalilah
Format: Thesis
Language:English
Published: 2014
Subjects:
Online Access:http://eprints.utm.my/50730/25/JalilahRubaiMFS2014.pdf
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author Rubai, Jalilah
author_facet Rubai, Jalilah
author_sort Rubai, Jalilah
collection ePrints
description The presence of blood clot in the blood stream can lead to partial or even complete blockage of the blood vessel. The condition can get worse in a stenosed artery. The clot will alter the flow field and modify the pressure distribution. To understand the changes in the blood flow due to presence of the clot, the fluid mechanics of blood flow in a stenosed artery with a clot is studied through a mathematical analysis. Blood is modelled as an incompressible Newtonian fluid and the flow is treated to be axi-symmetric. The artery is modelled as a rigid tube with a stenosis and an elongated shape representing a clot inside it. Both the stenosis and the clot are axi-symmetric over the length of the artery. The governing equations of motion are solved by using regular perturbation analysis. The results show that in the presence of the clot, the important physiologically flow characteristics such as pressure gradient and wall shear stress vary markedly across the stenotic lesion. The height of the peak of the clot increases the wall shear stress. Results are sensitive to not only the geometry of the stenotic wall but also to the position of the clot.
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spelling utm.eprints-507302020-07-10T09:42:26Z http://eprints.utm.my/50730/ Modeling of blood flow in stenosed artery with a clot Rubai, Jalilah QA Mathematics The presence of blood clot in the blood stream can lead to partial or even complete blockage of the blood vessel. The condition can get worse in a stenosed artery. The clot will alter the flow field and modify the pressure distribution. To understand the changes in the blood flow due to presence of the clot, the fluid mechanics of blood flow in a stenosed artery with a clot is studied through a mathematical analysis. Blood is modelled as an incompressible Newtonian fluid and the flow is treated to be axi-symmetric. The artery is modelled as a rigid tube with a stenosis and an elongated shape representing a clot inside it. Both the stenosis and the clot are axi-symmetric over the length of the artery. The governing equations of motion are solved by using regular perturbation analysis. The results show that in the presence of the clot, the important physiologically flow characteristics such as pressure gradient and wall shear stress vary markedly across the stenotic lesion. The height of the peak of the clot increases the wall shear stress. Results are sensitive to not only the geometry of the stenotic wall but also to the position of the clot. 2014-06 Thesis NonPeerReviewed application/pdf en http://eprints.utm.my/50730/25/JalilahRubaiMFS2014.pdf Rubai, Jalilah (2014) Modeling of blood flow in stenosed artery with a clot. Masters thesis, Universiti Teknologi Malaysia, Faculty of Science. http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:85434
spellingShingle QA Mathematics
Rubai, Jalilah
Modeling of blood flow in stenosed artery with a clot
title Modeling of blood flow in stenosed artery with a clot
title_full Modeling of blood flow in stenosed artery with a clot
title_fullStr Modeling of blood flow in stenosed artery with a clot
title_full_unstemmed Modeling of blood flow in stenosed artery with a clot
title_short Modeling of blood flow in stenosed artery with a clot
title_sort modeling of blood flow in stenosed artery with a clot
topic QA Mathematics
url http://eprints.utm.my/50730/25/JalilahRubaiMFS2014.pdf
work_keys_str_mv AT rubaijalilah modelingofbloodflowinstenosedarterywithaclot