Effect of solvent/additives ratio on cellulose acetate dialysis membrane formation and urea clearance

Cellulose acetate flat sheet asymmetric dialysis membranes were fabricated via phase inversion process using acetic acid as the solvent. The effects of solvent to polymeric additives (polyethylene glycol; PEG 600) ratio on the morphology and urea clearance of the dialysis membranes were investigated...

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Main Authors: Idris, Ani, Lee, Kuan Yet
Format: Conference or Workshop Item
Language:English
Published: 2005
Subjects:
Online Access:http://eprints.utm.my/5267/1/AniIdris2005_EffectOfSolventAdditivesRatio.pdf
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author Idris, Ani
Lee, Kuan Yet
author_facet Idris, Ani
Lee, Kuan Yet
author_sort Idris, Ani
collection ePrints
description Cellulose acetate flat sheet asymmetric dialysis membranes were fabricated via phase inversion process using acetic acid as the solvent. The effects of solvent to polymeric additives (polyethylene glycol; PEG 600) ratio on the morphology and urea clearance of the dialysis membranes were investigated. Dialysis membranes from six different formulations were tasted using phase inversion method and were tested using single layer dialysis apparatus. The performances of the obtained membranes were tested using 1 mg/mL urea solution and the morphology of the membranes was characterized using scanning electron microscope. It was found that higher acetic acid/PEG ratio provide better urea clearance performance. Furthermore, the amount of additives strongly affects the membrane structure. Higher acetic acid/PEG ratio induced the formation of finger like structure macrovoids whilst dense spongy structures were found with lower acetic acid/PEG ratios. However, control experiment showed that the presence of PEG in the dope formulations is essential in order to increase the dialysis membrane performance.
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spelling utm.eprints-52672010-06-01T15:28:19Z http://eprints.utm.my/5267/ Effect of solvent/additives ratio on cellulose acetate dialysis membrane formation and urea clearance Idris, Ani Lee, Kuan Yet T Technology (General) Cellulose acetate flat sheet asymmetric dialysis membranes were fabricated via phase inversion process using acetic acid as the solvent. The effects of solvent to polymeric additives (polyethylene glycol; PEG 600) ratio on the morphology and urea clearance of the dialysis membranes were investigated. Dialysis membranes from six different formulations were tasted using phase inversion method and were tested using single layer dialysis apparatus. The performances of the obtained membranes were tested using 1 mg/mL urea solution and the morphology of the membranes was characterized using scanning electron microscope. It was found that higher acetic acid/PEG ratio provide better urea clearance performance. Furthermore, the amount of additives strongly affects the membrane structure. Higher acetic acid/PEG ratio induced the formation of finger like structure macrovoids whilst dense spongy structures were found with lower acetic acid/PEG ratios. However, control experiment showed that the presence of PEG in the dope formulations is essential in order to increase the dialysis membrane performance. 2005 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.utm.my/5267/1/AniIdris2005_EffectOfSolventAdditivesRatio.pdf Idris, Ani and Lee, Kuan Yet (2005) Effect of solvent/additives ratio on cellulose acetate dialysis membrane formation and urea clearance. In: Advanced Technology Congress, 6-8 December 2005, Putrajaya Marriott Hotel, Putrajaya.
spellingShingle T Technology (General)
Idris, Ani
Lee, Kuan Yet
Effect of solvent/additives ratio on cellulose acetate dialysis membrane formation and urea clearance
title Effect of solvent/additives ratio on cellulose acetate dialysis membrane formation and urea clearance
title_full Effect of solvent/additives ratio on cellulose acetate dialysis membrane formation and urea clearance
title_fullStr Effect of solvent/additives ratio on cellulose acetate dialysis membrane formation and urea clearance
title_full_unstemmed Effect of solvent/additives ratio on cellulose acetate dialysis membrane formation and urea clearance
title_short Effect of solvent/additives ratio on cellulose acetate dialysis membrane formation and urea clearance
title_sort effect of solvent additives ratio on cellulose acetate dialysis membrane formation and urea clearance
topic T Technology (General)
url http://eprints.utm.my/5267/1/AniIdris2005_EffectOfSolventAdditivesRatio.pdf
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